| 1 | Duke Of EarlGene Chandler | 1 | Chart history → |
| 2 | Hey! BabyBruce Channel | 5 | Chart history → |
| 3 | The WandererDion | 2 | Chart history → |
| 4 | Break It To Me GentlyBrenda Lee | 6 | Chart history → |
| 5 | The TwistChubby Checker | 4 | Chart history → |
| 6 | Crying In The RainThe Everly Brothers | 8 | Chart history → |
| 7 | NormanSue Thompson | 3 | Chart history → |
| 8 | Midnight In MoscowKenny Ball and his Jazzmen | 16 | Chart history → |
| 9 | Peppermint Twist - Part IJoey Dee & the Starliters | 7 | Chart history → |
| 10 | Chip ChipGene McDaniels | 11 | Chart history → |
| 11 | Dear Lady TwistGary U.S. Bonds | 9 | Chart history → |
| 12 | Let Me InThe Sensations | 17 | Chart history → |
| 13 | Don't Break The Heart That Loves YouConnie Francis | 23 | Chart history → |
| 14 | A Little Bitty TearBurl Ives | 10 | Chart history → |
| 15 | Baby It's YouThe Shirelles | 14 | Chart history → |
| 16 | Her Royal MajestyJames Darren | 21 | Chart history → |
| 17 | Percolator (Twist)Billy Joe & The Checkmates | 19 | Chart history → |
| 18 | TuffAce Cannon | 18 | Chart history → |
| 19 | I'm Blue (The Gong-Gong Song)The Ikettes | 20 | Chart history → |
| 20 | What's Your NameDon & Juan | 26 | Chart history → |
| 21 | Smoky PlacesThe Corsairs Featuring Jay "Bird" Uzzell | 24 | Chart history → |
| 22 | My Boomerang Won't Come BackCharlie Drake | 25 | Chart history → |
| 23 | I Know (You Don't Love Me No More)Barbara George | 15 | Chart history → |
| 24 | The Cajun QueenJimmy Dean | 22 | Chart history → |
| 25 | Cotton FieldsThe Highwaymen | 13 | Chart history → |
| 26 | To A Sleeping BeautyJimmy Dean | 29 | Chart history → |
| 27 | Twistin' The Night AwaySam Cooke | 33 | Chart history → |
| 28 | She's Got YouPatsy Cline | 36 | Chart history → |
| 29 | Can't Help Falling In LoveElvis Presley With The Jordanaires | 12 | Listen & explore → |
| 30 | Dream Baby (How Long Must I Dream)Roy Orbison | 53 | Chart history → |
| 31 | Hey, Let's TwistJoey Dee & the Starliters | 46 | Chart history → |
| 32 | I'll See You In My DreamsPat Boone | 40 | Chart history → |
| 33 | Surfer's StompThe Marketts | 31 | Chart history → |
| 34 | Twistin' PostmanThe Marvelettes | 44 | Chart history → |
| 35 | Drums Are My BeatSandy Nelson | 41 | Chart history → |
| 36 | Chattanooga Choo ChooFloyd Cramer | 38 | Chart history → |
| 37 | Irresistible YouBobby Darin | 30 | Chart history → |
| 38 | Where Have All The Flowers GoneThe Kingston Trio | 45 | Chart history → |
| 39 | He Knows I Love Him Too MuchThe Paris Sisters | 50 | Chart history → |
| 40 | (Do The New) ContinentalThe Dovells | 52 | Chart history → |
| 41 | Come Back Silly GirlThe Lettermen | 58 | Chart history → |
| 42 | JamieEddie Holland | 56 | Chart history → |
| 43 | What's So Good About Good-byThe Miracles | 35 | Chart history → |
| 44 | Lizzie BordenThe Chad Mitchell Trio | 57 | Chart history → |
| 45 | (I've Got) BonnieBobby Rydell | 66 | Chart history → |
| 46 | ShadrackBrook Benton | 27 | Chart history → |
| 47 | Afrikaan BeatBert Kaempfert And His Orchestra | 43 | Chart history → |
| 48 | Town Without PityGene Pitney | 32 | Chart history → |
| 49 | She's Everything (I Wanted You To Be)Ral Donner | 28 | Chart history → |
| 50 | The Greatest HurtJackie Wilson | 34 | Chart history → |
| 51 | That's My PaSheb Wooley | 51 | Chart history → |
| 52 | Cry To MeSolomon Burke | 55 | Chart history → |
| 53 | Dreamy EyesJohnny Tillotson | 65 | Chart history → |
| 54 | You Win AgainFats Domino | 64 | Chart history → |
| 55 | B'wa Nina (Pretty Girl)The Tokens | 59 | Chart history → |
| 56 | EcstasyBen E. King | 61 | Chart history → |
| 57 | Please Don't Ask About BarbaraBobby Vee | 81 | Chart history → |
| 58 | My Melancholy BabyThe Marcels | 62 | Chart history → |
| 59 | Our AnniversaryShep And The Limelites | 63 | Chart history → |
| 60 | Slow Twistin'Chubby Checker (with Dee Dee Sharp) | — | Chart history → |
| 61 | Walk On The Wild SideBrook Benton | 71 | Chart history → |
| 62 | Letter Full Of TearsGladys Knight And The Pips | 37 | Chart history → |
| 63 | Pop-EyeHuey Smith | 69 | Chart history → |
| 64 | Love Me Warm And TenderPaul Anka | 85 | Chart history → |
| 65 | Bandit Of My DreamsEddie Hodges | 72 | Chart history → |
| 66 | Let Me Call You SweetheartTimi Yuro | 67 | Chart history → |
| 67 | Love LettersKetty Lester | 84 | Chart history → |
| 68 | Blue Water LineThe Brothers Four | 70 | Chart history → |
| 69 | Lose HerBobby Rydell | 79 | Chart history → |
| 70 | BermudaLinda Scott | 78 | Chart history → |
| 71 | Tears And LaughterDinah Washington | 73 | Chart history → |
| 72 | YessireeLinda Scott | 74 | Chart history → |
| 73 | Something's Got A Hold On MeEtta James | 86 | Chart history → |
| 74 | Cry Baby CryThe Angels | 83 | Chart history → |
| 75 | You Better Move OnArthur Alexander | 87 | Chart history → |
| 76 | Nut RockerB. Bumble & The Stingers | — | Chart history → |
| 77 | Mashed Potato TimeDee Dee Sharp | — | Chart history → |
| 78 | Yes IndeedPete Fountain | 80 | Chart history → |
| 79 | The Alvin TwistThe Chipmunks With David Seville | — | Chart history → |
| 80 | Pictures In The FirePat Boone | 82 | Chart history → |
| 81 | Johnny AngelShelley Fabares | — | Chart history → |
| 82 | Oliver TwistRod McKuen | 77 | Chart history → |
| 83 | SurfinThe Beach Boys | 90 | Chart history → |
| 84 | Young WorldRick Nelson | — | Chart history → |
| 85 | When My Little Girl Is SmilingThe Drifters | 94 | Chart history → |
| 86 | Love Is The Sweetest ThingSaverio Saridis | 89 | Chart history → |
| 87 | I Surrender, DearAretha Franklin | 93 | Chart history → |
| 88 | Do You Know How To TwistHank Ballard | — | Chart history → |
| 89 | Lover PleaseClyde McPhatter | — | Chart history → |
| 90 | She Can't Find Her KeysPaul Petersen | — | Chart history → |
| 91 | Joey BabyAnita & Th' So-And-So's | 95 | Chart history → |
| 92 | Dear OneLarry Finnegan | 100 | Chart history → |
| 93 | Ida JaneFats Domino | — | Chart history → |
| 94 | Baby It's Cold OutsideRay Charles & Betty Carter | — | Chart history → |
| 95 | Patti AnnJohnny Crawford | — | Chart history → |
| 96 | Aw Shucks, Hush Your MouthJimmy Reed | 97 | Chart history → |
| 97 | The Ballad Of Thunder RoadRobert Mitchum | 98 | Chart history → |
| 98 | Midnight Special, Part 1Jimmy Smith | — | Chart history → |
| 99 | Lollipops And RosesJack Jones | — | Chart history → |
| 100 | (Quarter To Four) StompThe Stompers | — | Chart history → |