| 1 | Gold DiggerKanye West Featuring Jamie Foxx | 1 | Chart history → |
| 2 | Run It!Chris Brown | 2 | Chart history → |
| 3 | My HumpsThe Black Eyed Peas | 3 | Chart history → |
| 4 | Soul SurvivorYoung Jeezy Featuring Akon | 4 | Chart history → |
| 5 | PhotographNickelback | 5 | Chart history → |
| 6 | We Be Burnin'Sean Paul | 6 | Chart history → |
| 7 | Because Of YouKelly Clarkson | 8 | Chart history → |
| 8 | I'm SprungT-Pain | 11 | Chart history → |
| 9 | Shake It OffMariah Carey | 9 | Chart history → |
| 10 | Sugar, We're Goin' DownFall Out Boy | 10 | Chart history → |
| 11 | Like YouBow Wow Featuring Ciara | 7 | Chart history → |
| 12 | Wake Me Up When September EndsGreen Day | 12 | Chart history → |
| 13 | Laffy TaffyD4L | 18 | Chart history → |
| 14 | Girl ToniteTwista Featuring Trey Songz | 16 | Chart history → |
| 15 | You And MeLifehouse | 13 | Chart history → |
| 16 | Stay FlyThree 6 Mafia Featuring Young Buck & Eightball & MJG | 19 | Chart history → |
| 17 | I Think They Like MeDem Franchize Boyz Featuring Jermaine Dupri, Da Brat & Bow Wow | 20 | Chart history → |
| 18 | StickwituThe Pussycat Dolls | 25 | Chart history → |
| 19 | Your BodyPretty Ricky | 14 | Chart history → |
| 20 | Don't Forget About UsMariah Carey | 26 | Chart history → |
| 21 | Beverly HillsWeezer | 15 | Chart history → |
| 22 | Dance, DanceFall Out Boy | 32 | Chart history → |
| 23 | One WishRay J | 30 | Chart history → |
| 24 | Here We GoTrina Featuring Kelly Rowland | 28 | Chart history → |
| 25 | PlayDavid Banner | 17 | Chart history → |
| 26 | We Belong TogetherMariah Carey | 22 | Chart history → |
| 27 | Hung UpMadonna | 21 | Listen & explore → |
| 28 | Feel Good IncGorillaz | 23 | Chart history → |
| 29 | There It Go! (The Whistle Song)Juelz Santana | 29 | Chart history → |
| 30 | Don't ChaThe Pussycat Dolls Featuring Busta Rhymes | 24 | Chart history → |
| 31 | Lighters UpLil' Kim | 34 | Chart history → |
| 32 | Tequila Makes Her Clothes Fall OffJoe Nichols | 41 | Chart history → |
| 33 | BoyfriendAshlee Simpson | 27 | Chart history → |
| 34 | Behind These Hazel EyesKelly Clarkson | 31 | Chart history → |
| 35 | UnbreakableAlicia Keys | 39 | Chart history → |
| 36 | I Should Have CheatedKeyshia Cole | 35 | Chart history → |
| 37 | Pon de ReplayRihanna | 33 | Chart history → |
| 38 | Listen To Your HeartD.H.T. | 36 | Chart history → |
| 39 | LuxuriousGwen Stefani | 55 | Chart history → |
| 40 | Come A Little CloserDierks Bentley | 43 | Chart history → |
| 41 | ShakeYing Yang Twins Featuring Pitbull | 44 | Chart history → |
| 42 | More Than WordsFrankie J | 37 | Chart history → |
| 43 | Belly Dancer (Bananza)Akon | 40 | Chart history → |
| 44 | Skin (Sarabeth)Rascal Flatts | 46 | Chart history → |
| 45 | Lose ControlMissy Elliott Featuring Ciara & Fat Man Scoop | 38 | Chart history → |
| 46 | Who You'd Be TodayKenny Chesney | 49 | Chart history → |
| 47 | Heard 'Em SayKanye West Featuring Adam Levine | 56 | Chart history → |
| 48 | Jesus, Take The WheelCarrie Underwood | — | Chart history → |
| 49 | Better LifeKeith Urban | 47 | Chart history → |
| 50 | La TorturaShakira Feat. Alejandro Sanz | 42 | Chart history → |
| 51 | Dirty Little SecretThe All-American Rejects | 50 | Chart history → |
| 52 | Don't LieThe Black Eyed Peas | 45 | Chart history → |
| 53 | Best I Ever HadGary Allan | 51 | Chart history → |
| 54 | Like We Never Loved At AllFaith Hill | 58 | Chart history → |
| 55 | I'm Feeling YouSantana Featuring Michelle Branch & The Wreckers | 81 | Chart history → |
| 56 | Can I Have It Like ThatPharrell Featuring Gwen Stefani | 76 | Chart history → |
| 57 | CoolGwen Stefani | 57 | Chart history → |
| 58 | Honky Tonk BadonkadonkTrace Adkins | 70 | Chart history → |
| 59 | Must Be Doin' Somethin' RightBilly Currington | 62 | Chart history → |
| 60 | Probably Wouldn't Be This WayLeAnn Rimes | 54 | Chart history → |
| 61 | Just The GirlThe Click Five | 52 | Chart history → |
| 62 | Something To Be Proud OfMontgomery Gentry | 61 | Chart history → |
| 63 | You're Like Comin' HomeLonestar | 64 | Chart history → |
| 64 | Window Shopper50 Cent | 82 | Chart history → |
| 65 | If It's Lovin' That You WantRihanna | 65 | Chart history → |
| 66 | Outta Control (Remix)50 Cent Feat. Mobb Deep | 53 | Chart history → |
| 67 | Big Blue NoteToby Keith | 66 | Chart history → |
| 68 | Good Ride CowboyGarth Brooks | 67 | Chart history → |
| 69 | Redneck Yacht ClubCraig Morgan | 63 | Chart history → |
| 70 | BoondocksLittle Big Town | 73 | Listen & explore → |
| 71 | Better DaysGoo Goo Dolls | 77 | Chart history → |
| 72 | Check On ItBeyonce Featuring Slim Thug | — | Chart history → |
| 73 | Stay With Me (Brass Bed)Josh Gracin | 60 | Chart history → |
| 74 | Hustler's Ambition50 Cent | 79 | Chart history → |
| 75 | HomeMichael Buble | 72 | Chart history → |
| 76 | She Let Herself GoGeorge Strait | 84 | Chart history → |
| 77 | Billy's Got His Beer Goggles OnNeal McCoy | 75 | Chart history → |
| 78 | You're BeautifulJames Blunt | 88 | Chart history → |
| 79 | Doesn't Remind MeAudioslave | 69 | Chart history → |
| 80 | Turn It UpChamillionaire Featuring Lil' Flip | 91 | Chart history → |
| 81 | PresidentialYoungBloodZ | 83 | Chart history → |
| 82 | DOAFoo Fighters | 86 | Chart history → |
| 83 | A Real Fine Place To StartSara Evans | 74 | Chart history → |
| 84 | GrillzNelly Featuring Paul Wall, Ali & Gipp | — | Chart history → |
| 85 | BaddYing Yang Twins Featuring Mike Jones & Mr. ColliPark | 68 | Chart history → |
| 86 | NakedMarques Houston | 59 | Chart history → |
| 87 | Bat CountryAvenged Sevenfold | 87 | Chart history → |
| 88 | Soul Meets BodyDeath Cab For Cutie | 92 | Chart history → |
| 89 | Somebody's HeroJamie O'Neal | 78 | Chart history → |
| 90 | Miss Me BabyChris Cagle | 95 | Chart history → |
| 91 | FiremanLil Wayne | — | Chart history → |
| 92 | Save MeShinedown | — | Chart history → |
| 93 | OnlyNine Inch Nails | 97 | Chart history → |
| 94 | This Is How A Heart BreaksRob Thomas | 89 | Chart history → |
| 95 | Seasons Of LoveCast Of Rent | — | Chart history → |
| 96 | Good Is GoodSheryl Crow | 85 | Chart history → |
| 97 | Have A Nice DayBon Jovi | 93 | Chart history → |
| 98 | HypnotizeSystem Of A Down | — | Chart history → |
| 99 | StarsSwitchfoot | — | Chart history → |
| 100 | All These Things That I've DoneThe Killers | 94 | Chart history → |