| 1 | Don't Forget About UsMariah Carey | 2 | Chart history → |
| 2 | Run It!Chris Brown | 1 | Chart history → |
| 3 | GrillzNelly Featuring Paul Wall, Ali & Gipp | 4 | Chart history → |
| 4 | Laffy TaffyD4L | 3 | Chart history → |
| 5 | StickwituThe Pussycat Dolls | 7 | Chart history → |
| 6 | PhotographNickelback | 5 | Chart history → |
| 7 | Gold DiggerKanye West Featuring Jamie Foxx | 6 | Chart history → |
| 8 | Check On ItBeyonce Featuring Slim Thug | 18 | Chart history → |
| 9 | Because Of YouKelly Clarkson | 10 | Chart history → |
| 10 | There It Go! (The Whistle Song)Juelz Santana | 12 | Chart history → |
| 11 | My HumpsThe Black Eyed Peas | 9 | Chart history → |
| 12 | One WishRay J | 16 | Chart history → |
| 13 | Stay FlyThree 6 Mafia Featuring Young Buck & Eightball & MJG | 13 | Chart history → |
| 14 | Soul SurvivorYoung Jeezy Featuring Akon | 11 | Chart history → |
| 15 | I Think They Like MeDem Franchize Boyz Featuring Jermaine Dupri, Da Brat & Bow Wow | 17 | Chart history → |
| 16 | When I'm GoneEminem | 8 | Chart history → |
| 17 | I'm SprungT-Pain | 14 | Chart history → |
| 18 | Here We GoTrina Featuring Kelly Rowland | 20 | Chart history → |
| 19 | We Be Burnin'Sean Paul | 15 | Chart history → |
| 20 | Be Without YouMary J. Blige | 25 | Chart history → |
| 21 | Hung UpMadonna | 19 | Listen & explore → |
| 22 | Sugar, We're Goin' DownFall Out Boy | 21 | Chart history → |
| 23 | You're BeautifulJames Blunt | 22 | Chart history → |
| 24 | Dance, DanceFall Out Boy | 24 | Chart history → |
| 25 | LuxuriousGwen Stefani | 23 | Chart history → |
| 26 | So SickNe-Yo | 35 | Chart history → |
| 27 | Dirty Little SecretThe All-American Rejects | 28 | Chart history → |
| 28 | Heard 'Em SayKanye West Featuring Adam Levine | 26 | Chart history → |
| 29 | You And MeLifehouse | 29 | Chart history → |
| 30 | Feel Good IncGorillaz | 33 | Chart history → |
| 31 | Jesus, Take The WheelCarrie Underwood | 42 | Chart history → |
| 32 | FiremanLil Wayne | 36 | Chart history → |
| 33 | Wake Me Up When September EndsGreen Day | 30 | Chart history → |
| 34 | I Should Have CheatedKeyshia Cole | 31 | Chart history → |
| 35 | Kryptonite (I'm On It)Purple Ribbon All-Stars | 43 | Chart history → |
| 36 | If It's Lovin' That You WantRihanna | 38 | Chart history → |
| 37 | Beverly HillsWeezer | 37 | Chart history → |
| 38 | Honky Tonk BadonkadonkTrace Adkins | 46 | Chart history → |
| 39 | Must Be Doin' Somethin' RightBilly Currington | 44 | Chart history → |
| 40 | Come A Little CloserDierks Bentley | 39 | Chart history → |
| 41 | Shake It OffMariah Carey | 32 | Chart history → |
| 42 | Girl ToniteTwista Featuring Trey Songz | 34 | Chart history → |
| 43 | Turn It UpChamillionaire Featuring Lil' Flip | 48 | Chart history → |
| 44 | Tequila Makes Her Clothes Fall OffJoe Nichols | 41 | Chart history → |
| 45 | Don't ChaThe Pussycat Dolls Featuring Busta Rhymes | 45 | Chart history → |
| 46 | Window Shopper50 Cent | 27 | Chart history → |
| 47 | UnpredictableJamie Foxx Featuring Ludacris | 58 | Chart history → |
| 48 | GeorgiaLudacris & Field Mob Featuring Jamie Foxx | — | Chart history → |
| 49 | UnbreakableAlicia Keys | 40 | Chart history → |
| 50 | We Belong TogetherMariah Carey | 49 | Chart history → |
| 51 | UnwrittenNatasha Bedingfield | 60 | Chart history → |
| 52 | Shake ThatEminem Featuring Nate Dogg | 76 | Chart history → |
| 53 | Like We Never Loved At AllFaith Hill | 51 | Chart history → |
| 54 | She Let Herself GoGeorge Strait | 54 | Chart history → |
| 55 | Everytime We TouchCascada | 62 | Chart history → |
| 56 | Who You'd Be TodayKenny Chesney | 47 | Chart history → |
| 57 | Better DaysGoo Goo Dolls | 59 | Chart history → |
| 58 | BoondocksLittle Big Town | 56 | Listen & explore → |
| 59 | Good Ride CowboyGarth Brooks | 61 | Chart history → |
| 60 | Soul Meets BodyDeath Cab For Cutie | 81 | Chart history → |
| 61 | Don't BotherShakira | 52 | Chart history → |
| 62 | When I Get Where I'm GoingBrad Paisley Featuring Dolly Parton | 72 | Chart history → |
| 63 | HypnotizeSystem Of A Down | 65 | Chart history → |
| 64 | Nasty GirlThe Notorious B.I.G. Featuring Diddy, Nelly, Jagged Edge & Avery Storm | 83 | Chart history → |
| 65 | Twisted TransistorKorn | 64 | Chart history → |
| 66 | RompeDaddy Yankee | 70 | Chart history → |
| 67 | Touch ItBusta Rhymes | 88 | Chart history → |
| 68 | Gotta GoTrey Songz | 67 | Chart history → |
| 69 | Miss Me BabyChris Cagle | 71 | Chart history → |
| 70 | Pump ItThe Black Eyed Peas | 90 | Chart history → |
| 71 | ShakeYing Yang Twins Featuring Pitbull | 63 | Chart history → |
| 72 | RodeoJuvenile | 80 | Chart history → |
| 73 | Fresh AzimizBow Wow Featuring J-Kwon & Jermaine Dupri | 84 | Chart history → |
| 74 | Seasons Of LoveCast Of Rent | 53 | Chart history → |
| 75 | Better LifeKeith Urban | 66 | Chart history → |
| 76 | L.O.V.E.Ashlee Simpson | — | Chart history → |
| 77 | Big Blue NoteToby Keith | 55 | Chart history → |
| 78 | Bat CountryAvenged Sevenfold | 79 | Chart history → |
| 79 | Just Might (Make Me Believe)Sugarland | 75 | Chart history → |
| 80 | Save MeShinedown | 73 | Chart history → |
| 81 | Perfect SituationWeezer | 92 | Chart history → |
| 82 | DOAFoo Fighters | 68 | Chart history → |
| 83 | Looking For YouKirk Franklin | 77 | Chart history → |
| 84 | More Than WordsFrankie J | 69 | Chart history → |
| 85 | RakataWisin & Yandel | 99 | Chart history → |
| 86 | Tonight I Wanna CryKeith Urban | — | Chart history → |
| 87 | I'm N Luv (Wit A Stripper)T-Pain Featuring Mike Jones | — | Chart history → |
| 88 | My Old FriendTim McGraw | 89 | Chart history → |
| 89 | Yo (Excuse Me Miss)Chris Brown | — | Chart history → |
| 90 | KeroseneMiranda Lambert | — | Chart history → |
| 91 | PresidentialYoungBloodZ | — | Chart history → |
| 92 | BoyfriendAshlee Simpson | 86 | Chart history → |
| 93 | Your ManJosh Turner | 96 | Chart history → |
| 94 | RemedySeether | — | Chart history → |
| 95 | BelieveBrooks & Dunn | 97 | Chart history → |
| 96 | Hit The FloorTwista Featuring Pitbull | 100 | Chart history → |
| 97 | Confessions Of A Broken Heart (Daughter To Father)Lindsay Lohan | 57 | Chart history → |
| 98 | She Don't Tell Me ToMontgomery Gentry | — | Chart history → |
| 99 | Have A Nice DayBon Jovi | 95 | Chart history → |
| 100 | Comin' To Your CityBig & Rich | 93 | Chart history → |