| 1 | Bad DayDaniel Powter | 1 | Chart history → |
| 2 | TemperatureSean Paul | 2 | Chart history → |
| 3 | What You KnowT.I. | 4 | Chart history → |
| 4 | You're BeautifulJames Blunt | 3 | Chart history → |
| 5 | Be Without YouMary J. Blige | 5 | Chart history → |
| 6 | UnwrittenNatasha Bedingfield | 6 | Chart history → |
| 7 | Lean Wit It, Rock Wit ItDem Franchize Boyz Featuring Lil Peanut & Charlay | 8 | Chart history → |
| 8 | What Hurts The MostRascal Flatts | 52 | Chart history → |
| 9 | Ms. New BootyBubba Sparxxx Featuring Ying Yang Twins & Mr. ColliPark | 9 | Chart history → |
| 10 | So SickNe-Yo | 7 | Chart history → |
| 11 | Yo (Excuse Me Miss)Chris Brown | 11 | Chart history → |
| 12 | Walk AwayKelly Clarkson | 13 | Chart history → |
| 13 | Ridin'Chamillionaire Featuring Krayzie Bone | 17 | Chart history → |
| 14 | BeepThe Pussycat Dolls Featuring will.i.am | 14 | Chart history → |
| 15 | Stupid GirlsP!nk | 30 | Chart history → |
| 16 | Everytime We TouchCascada | 12 | Chart history → |
| 17 | I'm N Luv (Wit A Stripper)T-Pain Featuring Mike Jones | 10 | Chart history → |
| 18 | Touch ItBusta Rhymes | 16 | Chart history → |
| 19 | Check On ItBeyonce Featuring Slim Thug | 15 | Chart history → |
| 20 | Move AlongThe All-American Rejects | 18 | Chart history → |
| 21 | Poppin' My CollarThree 6 Mafia | 22 | Chart history → |
| 22 | GrillzNelly Featuring Paul Wall, Ali & Gipp | 19 | Chart history → |
| 23 | Savin' MeNickelback | 21 | Chart history → |
| 24 | Dani CaliforniaRed Hot Chili Peppers | — | Chart history → |
| 25 | LoveKeyshia Cole | 20 | Chart history → |
| 26 | Over My Head (Cable Car)The Fray | 31 | Chart history → |
| 27 | Who Says You Can't Go HomeBon Jovi | 23 | Chart history → |
| 28 | RompeDaddy Yankee | 24 | Chart history → |
| 29 | Dance, DanceFall Out Boy | 25 | Chart history → |
| 30 | SOSRihanna | 33 | Chart history → |
| 31 | Fresh AzimizBow Wow Featuring J-Kwon & Jermaine Dupri | 32 | Chart history → |
| 32 | Because Of YouKelly Clarkson | 26 | Chart history → |
| 33 | Hips Don't LieShakira Featuring Wyclef Jean | 41 | Chart history → |
| 34 | When You're MadNe-Yo | 42 | Chart history → |
| 35 | Shake ThatEminem Featuring Nate Dogg | 27 | Chart history → |
| 36 | Dirty Little SecretThe All-American Rejects | 29 | Chart history → |
| 37 | Tonight I Wanna CryKeith Urban | 40 | Chart history → |
| 38 | Run It!Chris Brown | 36 | Chart history → |
| 39 | UnpredictableJamie Foxx Featuring Ludacris | 28 | Chart history → |
| 40 | For You I Will (Confidence)Teddy Geiger | 34 | Chart history → |
| 41 | Pump ItThe Black Eyed Peas | 35 | Chart history → |
| 42 | When The Stars Go BlueTim McGraw | 57 | Chart history → |
| 43 | Tell Me When To GoE-40 Featuring Keak Da Sneak | 38 | Chart history → |
| 44 | My HumpsThe Black Eyed Peas | 37 | Chart history → |
| 45 | GirlPaul Wall | 53 | Chart history → |
| 46 | Jesus, Take The WheelCarrie Underwood | 39 | Chart history → |
| 47 | Get Drunk And Be SomebodyToby Keith | 48 | Chart history → |
| 48 | PhotographNickelback | 43 | Chart history → |
| 49 | You And MeLifehouse | 45 | Chart history → |
| 50 | Gold DiggerKanye West Featuring Jamie Foxx | 44 | Chart history → |
| 51 | Girl Next DoorSaving Jane | 47 | Chart history → |
| 52 | What's Left Of MeNick Lachey | 54 | Chart history → |
| 53 | Ever The SameRob Thomas | 50 | Chart history → |
| 54 | Best Friend50 Cent & Olivia | 56 | Chart history → |
| 55 | Gettin' SomeShawnna | 67 | Chart history → |
| 56 | Every Day Is Exactly The SameNine Inch Nails | — | Chart history → |
| 57 | I Write Sins Not TragediesPanic! At The Disco | 51 | Chart history → |
| 58 | Upside DownJack Johnson | 58 | Chart history → |
| 59 | Beautiful LoveThe Afters | 96 | Chart history → |
| 60 | WhyJason Aldean | 65 | Chart history → |
| 61 | Looking For YouKirk Franklin | 61 | Chart history → |
| 62 | BelieveBrooks & Dunn | 62 | Chart history → |
| 63 | King Without A CrownMatisyahu | 55 | Chart history → |
| 64 | 4 MinutesAvant | 72 | Chart history → |
| 65 | The Real ThingBo Bice | 70 | Chart history → |
| 66 | Your ManJosh Turner | 59 | Chart history → |
| 67 | Nobody But MeBlake Shelton | 60 | Chart history → |
| 68 | Settle For A SlowdownDierks Bentley | 73 | Chart history → |
| 69 | RushAly & AJ | 68 | Chart history → |
| 70 | Something's Gotta GiveLeAnn Rimes | 75 | Chart history → |
| 71 | Living In Fast ForwardKenny Chesney | 64 | Chart history → |
| 72 | Snap Yo FingersLil Jon Featuring E-40 & Sean Paul Of The YoungBloodZ | 89 | Chart history → |
| 73 | Always On Your SideSheryl Crow & Sting | 74 | Chart history → |
| 74 | Wherever You AreJack Ingram | 81 | Chart history → |
| 75 | Black Horse & The Cherry TreeKT Tunstall | 86 | Chart history → |
| 76 | She Don't Tell Me ToMontgomery Gentry | 66 | Chart history → |
| 77 | A Little Less Sixteen Candles, A Little More Touch MeFall Out Boy | 80 | Chart history → |
| 78 | Can't Let GoAnthony Hamilton | 71 | Chart history → |
| 79 | In My MindHeather Headley | 77 | Chart history → |
| 80 | Gimme ThatChris Brown Featuring Lil Wayne | — | Chart history → |
| 81 | Back Like ThatGhostface Killah Featuring Ne-Yo | 76 | Chart history → |
| 82 | It's Goin' DownYung Joc | 95 | Chart history → |
| 83 | The Only Difference Between Martyrdom And Suicide Is Press CoveragePanic! At The Disco | 78 | Chart history → |
| 84 | The Lucky OneFaith Hill | 84 | Chart history → |
| 85 | Say IChristina Milian Featuring Young Jeezy | 98 | Chart history → |
| 86 | Where'd You GoFort Minor Featuring Holly Brook | — | Chart history → |
| 87 | Touch The SkyKanye West Featuring Lupe Fiasco | 69 | Chart history → |
| 88 | So WhatField Mob Featuring Ciara | — | Chart history → |
| 89 | Stay With YouGoo Goo Dolls | — | Chart history → |
| 90 | Enough CryinMary J. Blige Featuring Brook-Lyn | — | Chart history → |
| 91 | World Wide SuicidePearl Jam | 83 | Chart history → |
| 92 | Gold LionYeah Yeah Yeahs | 88 | Chart history → |
| 93 | SpeakGodsmack | 85 | Chart history → |
| 94 | Size Matters (Someday)Joe Nichols | 100 | Chart history → |
| 95 | Conceited (There's Something About Remy)Remy Ma | 92 | Chart history → |
| 96 | How To Save A LifeThe Fray | 93 | Chart history → |
| 97 | Lo Que Son Las CosasAnais | 79 | Chart history → |
| 98 | L.O.V.E.Ashlee Simpson | 87 | Chart history → |
| 99 | Every Time I Hear Your NameKeith Anderson | — | Chart history → |
| 100 | Good Luck CharmJagged Edge | — | Chart history → |