| 1 | London BridgeFergie | 1 | Chart history → |
| 2 | CrazyGnarls Barkley | 2 | Listen & explore → |
| 3 | PromiscuousNelly Furtado Featuring Timbaland | 3 | Chart history → |
| 4 | (When You Gonna) Give It Up To MeSean Paul Feat. Keyshia Cole | 6 | Chart history → |
| 5 | ButtonsThe Pussycat Dolls Featuring Snoop Dogg | 5 | Chart history → |
| 6 | Me & UCassie | 4 | Chart history → |
| 7 | Get UpCiara Featuring Chamillionaire | 21 | Chart history → |
| 8 | Ain't No Other ManChristina Aguilera | 8 | Chart history → |
| 9 | Sexy LoveNe-Yo | 9 | Chart history → |
| 10 | I Write Sins Not TragediesPanic! At The Disco | 7 | Chart history → |
| 11 | Far AwayNickelback | 23 | Chart history → |
| 12 | Do It To ItCherish Featuring Sean Paul Of The YoungBloodZ | 14 | Chart history → |
| 13 | Shoulder LeanYoung Dro Featuring T.I. | 10 | Chart history → |
| 14 | U And DatE-40 Featuring T-Pain & Kandi Girl | 13 | Chart history → |
| 15 | Deja VuBeyonce Featuring Jay Z | 12 | Chart history → |
| 16 | Pullin' Me BackChingy Featuring Tyrese | 20 | Chart history → |
| 17 | Show StopperDanity Kane | — | Chart history → |
| 18 | Over My Head (Cable Car)The Fray | 11 | Chart history → |
| 19 | I Know You See ItYung Joc Featuring Brandy 'Ms. B.' Hambrick | 22 | Chart history → |
| 20 | It's Goin' DownYung Joc | 15 | Chart history → |
| 21 | BossyKelis Featuring Too $hort | 18 | Chart history → |
| 22 | Hips Don't LieShakira Featuring Wyclef Jean | 17 | Chart history → |
| 23 | Snap Yo FingersLil Jon Featuring E-40 & Sean Paul Of The YoungBloodZ | 19 | Chart history → |
| 24 | UnfaithfulRihanna | 16 | Chart history → |
| 25 | Call Me When You're SoberEvanescence | — | Chart history → |
| 26 | Chasing CarsSnow Patrol | 31 | Chart history → |
| 27 | Move AlongThe All-American Rejects | 25 | Chart history → |
| 28 | Dani CaliforniaRed Hot Chili Peppers | 26 | Chart history → |
| 29 | When You Were YoungThe Killers | 29 | Chart history → |
| 30 | Black Horse & The Cherry TreeKT Tunstall | 30 | Chart history → |
| 31 | SexyBackJustin Timberlake | 35 | Listen & explore → |
| 32 | Chain Hang LowJibbs | 39 | Chart history → |
| 33 | Ridin'Chamillionaire Featuring Krayzie Bone | 28 | Chart history → |
| 34 | Lips Of An AngelHinder | 49 | Chart history → |
| 35 | A Public AffairJessica Simpson | 24 | Chart history → |
| 36 | So WhatField Mob Featuring Ciara | 27 | Chart history → |
| 37 | Bad DayDaniel Powter | 32 | Chart history → |
| 38 | Savin' MeNickelback | 34 | Chart history → |
| 39 | Leave The PiecesThe Wreckers | 38 | Chart history → |
| 40 | Hate MeBlue October | 47 | Chart history → |
| 41 | UnwrittenNatasha Bedingfield | 37 | Chart history → |
| 42 | Call On MeJanet & Nelly | 44 | Chart history → |
| 43 | Brand New GirlfriendSteve Holy | 41 | Chart history → |
| 44 | About UsBrooke Hogan Featuring Paul Wall | 33 | Chart history → |
| 45 | What Hurts The MostRascal Flatts | 43 | Chart history → |
| 46 | If You're Going Through Hell (Before The Devil Even Knows)Rodney Atkins | 36 | Chart history → |
| 47 | SOSRihanna | 40 | Chart history → |
| 48 | Say GoodbyeChris Brown | 79 | Chart history → |
| 49 | Stars Are BlindParis Hilton | 42 | Chart history → |
| 50 | Life Is A HighwayRascal Flatts | 50 | Chart history → |
| 51 | How To Save A LifeThe Fray | 61 | Chart history → |
| 52 | Would You Go With MeJosh Turner | 57 | Chart history → |
| 53 | S.E.X.Lyfe Jennings | 52 | Chart history → |
| 54 | The RiddleFive For Fighting | 46 | Chart history → |
| 55 | Waiting On The World To ChangeJohn Mayer | 58 | Chart history → |
| 56 | Why You WannaT.I. | 48 | Chart history → |
| 57 | GalleryMario Vazquez | 70 | Chart history → |
| 58 | Show Me The MoneyPetey Pablo | — | Chart history → |
| 59 | Miss MurderAFI | 53 | Chart history → |
| 60 | Bring It On HomeLittle Big Town | 63 | Chart history → |
| 61 | Gimme ThatChris Brown Featuring Lil Wayne | 56 | Chart history → |
| 62 | I Loved Her FirstHeartland | 75 | Chart history → |
| 63 | SummertimeKenny Chesney | 59 | Chart history → |
| 64 | Steady, As She GoesThe Raconteurs | 65 | Chart history → |
| 65 | Crazy BitchBuckcherry | 69 | Chart history → |
| 66 | The Diary Of JaneBreaking Benjamin | 55 | Chart history → |
| 67 | Animal I Have BecomeThree Days Grace | 68 | Chart history → |
| 68 | TornLeToya | 60 | Chart history → |
| 69 | Tell Me BabyRed Hot Chili Peppers | — | Chart history → |
| 70 | Building BridgesBrooks & Dunn With Sheryl Crow & Vince Gill | 77 | Chart history → |
| 71 | The WorldBrad Paisley | 64 | Chart history → |
| 72 | I Call It LoveLionel Richie | 88 | Chart history → |
| 73 | Sunshine And SummertimeFaith Hill | 73 | Chart history → |
| 74 | Where'd You GoFort Minor Featuring Holly Brook | 51 | Chart history → |
| 75 | A Little Too LateToby Keith | 67 | Chart history → |
| 76 | Hustlin'Rick Ross | 54 | Chart history → |
| 77 | Through GlassStone Sour | 71 | Chart history → |
| 78 | EntourageOmarion | 85 | Chart history → |
| 79 | Money MakerLudacris Featuring Pharrell | 96 | Chart history → |
| 80 | Put Your Records OnCorinne Bailey Rae | 84 | Chart history → |
| 81 | SwingTrace Adkins | 82 | Chart history → |
| 82 | Me And My GangRascal Flatts | 62 | Chart history → |
| 83 | That GirlFrankie J Featuring Mannie Fresh & Chamillionaire | 100 | Chart history → |
| 84 | Everytime Tha Beat DropMonica Featuring Dem Franchize Boyz | 92 | Chart history → |
| 85 | Life Ain't Always BeautifulGary Allan | 66 | Chart history → |
| 86 | Stay With YouGoo Goo Dolls | 81 | Chart history → |
| 87 | Give It AwayGeorge Strait | 90 | Chart history → |
| 88 | It's Okay (One Blood)The Game Featuring Junior Reid | — | Chart history → |
| 89 | Every Mile A MemoryDierks Bentley | 95 | Chart history → |
| 90 | Too Little Too LateJoJo | — | Chart history → |
| 91 | The Kill (Bury Me)30 Seconds To Mars | 86 | Chart history → |
| 92 | Breathe (2 AM)Anna Nalick | 78 | Chart history → |
| 93 | Suddenly I SeeKT Tunstall | 89 | Chart history → |
| 94 | Ghetto Story Chapter 2Cham Featuring Alicia Keys | — | Chart history → |
| 95 | Face DownThe Red Jumpsuit Apparatus | 94 | Chart history → |
| 96 | Need A BossShareefa Featuring Ludacris | 99 | Chart history → |
| 97 | Not Ready To Make NiceDixie Chicks | 93 | Chart history → |
| 98 | MakeDamnSureTaking Back Sunday | 83 | Chart history → |
| 99 | Doing Too MuchPaula DeAnda Featuring Baby Bash | 74 | Chart history → |
| 100 | Enough CryinMary J. Blige Featuring Brook-Lyn | 87 | Chart history → |