| 1 | Money MakerLudacris Featuring Pharrell | 1 | Chart history → |
| 2 | Smack ThatAkon Featuring Eminem | 4 | Chart history → |
| 3 | Lips Of An AngelHinder | 3 | Chart history → |
| 4 | SexyBackJustin Timberlake | 2 | Listen & explore → |
| 5 | My LoveJustin Timberlake Featuring T.I. | 8 | Chart history → |
| 6 | How To Save A LifeThe Fray | 5 | Chart history → |
| 7 | Too Little Too LateJoJo | 7 | Chart history → |
| 8 | Chasing CarsSnow Patrol | 6 | Chart history → |
| 9 | Come To MeDiddy Featuring Nicole Scherzinger | 18 | Chart history → |
| 10 | Far AwayNickelback | 10 | Chart history → |
| 11 | Chain Hang LowJibbs | 9 | Chart history → |
| 12 | Say GoodbyeChris Brown | 14 | Chart history → |
| 13 | Show StopperDanity Kane | 12 | Chart history → |
| 14 | Call Me When You're SoberEvanescence | 13 | Chart history → |
| 15 | White & Nerdy"Weird Al" Yankovic | 11 | Chart history → |
| 16 | ManeaterNelly Furtado | 16 | Chart history → |
| 17 | London BridgeFergie | 15 | Chart history → |
| 18 | ButtonsThe Pussycat Dolls Featuring Snoop Dogg | 19 | Chart history → |
| 19 | FergaliciousFergie | 35 | Chart history → |
| 20 | Get UpCiara Featuring Chamillionaire | 20 | Chart history → |
| 21 | Shortie Like MineBow Wow Featuring Chris Brown & Johnta Austin | 44 | Chart history → |
| 22 | CrazyGnarls Barkley | 23 | Listen & explore → |
| 23 | Waiting On The World To ChangeJohn Mayer | 26 | Chart history → |
| 24 | Before He CheatsCarrie Underwood | 28 | Chart history → |
| 25 | Ring The AlarmBeyonce | 21 | Chart history → |
| 26 | Pullin' Me BackChingy Featuring Tyrese | 17 | Chart history → |
| 27 | Over My Head (Cable Car)The Fray | 25 | Chart history → |
| 28 | When You Were YoungThe Killers | 24 | Chart history → |
| 29 | I Know You See ItYung Joc Featuring Brandy 'Ms. B.' Hambrick | 22 | Chart history → |
| 30 | Sexy LoveNe-Yo | 27 | Chart history → |
| 31 | Walk It OutUnk | 43 | Chart history → |
| 32 | Stuntin' Like My DaddyBirdman & Lil Wayne | 51 | Chart history → |
| 33 | I Write Sins Not TragediesPanic! At The Disco | 29 | Chart history → |
| 34 | What Hurts The MostRascal Flatts | 31 | Chart history → |
| 35 | My Little GirlTim McGraw | 53 | Chart history → |
| 36 | I Loved Her FirstHeartland | 34 | Chart history → |
| 37 | GalleryMario Vazquez | 38 | Chart history → |
| 38 | HurtChristina Aguilera | 59 | Chart history → |
| 39 | PromiscuousNelly Furtado Featuring Timbaland | 30 | Chart history → |
| 40 | It Ends TonightThe All-American Rejects | 58 | Chart history → |
| 41 | I Wanna Love YouAkon Featuring Snoop Dogg | 56 | Chart history → |
| 42 | U And DatE-40 Featuring T-Pain & Kandi Girl | 33 | Chart history → |
| 43 | My WishRascal Flatts | 41 | Chart history → |
| 44 | (When You Gonna) Give It Up To MeSean Paul Feat. Keyshia Cole | 32 | Chart history → |
| 45 | Money In The BankLil Scrappy Featuring Young Buck | 55 | Chart history → |
| 46 | Move AlongThe All-American Rejects | 42 | Chart history → |
| 47 | Want ToSugarland | 49 | Chart history → |
| 48 | Every Mile A MemoryDierks Bentley | 60 | Chart history → |
| 49 | Hate MeBlue October | 37 | Chart history → |
| 50 | You Save MeKenny Chesney | 48 | Chart history → |
| 51 | S.E.X.Lyfe Jennings | 40 | Chart history → |
| 52 | That GirlFrankie J Featuring Mannie Fresh & Chamillionaire | 61 | Chart history → |
| 53 | Ain't No Other ManChristina Aguilera | 39 | Chart history → |
| 54 | We Fly HighJim Jones | 63 | Chart history → |
| 55 | Would You Go With MeJosh Turner | 46 | Chart history → |
| 56 | Welcome To The Black ParadeMy Chemical Romance | 64 | Chart history → |
| 57 | Once In A LifetimeKeith Urban | 52 | Chart history → |
| 58 | Show Me What You GotJAY-Z | 72 | Chart history → |
| 59 | Chicken Noodle Soup.Webstar & Young B Featuring The Voice Of Harlem | 57 | Chart history → |
| 60 | BostonAugustana | 54 | Chart history → |
| 61 | Tim McGrawTaylor Swift | 65 | Chart history → |
| 62 | Tell MeDiddy Featuring Christina Aguilera | — | Chart history → |
| 63 | Push ItRick Ross | 69 | Chart history → |
| 64 | Give It AwayGeorge Strait | 50 | Chart history → |
| 65 | Everytime Tha Beat DropMonica Featuring Dem Franchize Boyz | 62 | Chart history → |
| 66 | Love Me Or Hate Me (F**k You!!!!)Lady Sovereign | 81 | Chart history → |
| 67 | Take Me As I AmMary J. Blige | 68 | Chart history → |
| 68 | Need A BossShareefa Featuring Ludacris | 66 | Chart history → |
| 69 | Suddenly I SeeKT Tunstall | 76 | Chart history → |
| 70 | Tell Me BabyRed Hot Chili Peppers | 67 | Chart history → |
| 71 | The RiddleFive For Fighting | 70 | Chart history → |
| 72 | Right Where You Want MeJesse McCartney | 71 | Chart history → |
| 73 | I Call It LoveLionel Richie | 75 | Chart history → |
| 74 | Through GlassStone Sour | 79 | Chart history → |
| 75 | Walk Away (Remember Me)Paula DeAnda Featuring The DEY | 90 | Chart history → |
| 76 | Put Your Records OnCorinne Bailey Rae | 73 | Chart history → |
| 77 | She's EverythingBrad Paisley | 86 | Chart history → |
| 78 | The Pick Of DestinyTenacious D | — | Chart history → |
| 79 | Here It Goes AgainOK Go | 80 | Chart history → |
| 80 | It's Okay (One Blood)The Game Featuring Junior Reid | 78 | Chart history → |
| 81 | UnappreciatedCherish | 92 | Chart history → |
| 82 | The Kill (Bury Me)30 Seconds To Mars | 87 | Chart history → |
| 83 | Streetcorner SymphonyRob Thomas | 93 | Chart history → |
| 84 | Come Back To MeVanessa Hudgens | 82 | Chart history → |
| 85 | Call On MeJanet & Nelly | 74 | Chart history → |
| 86 | RockstarNickelback | 85 | Chart history → |
| 87 | IrreplaceableBeyonce | — | Chart history → |
| 88 | Brand New GirlfriendSteve Holy | 84 | Chart history → |
| 89 | MountainsLonestar | 99 | Chart history → |
| 90 | Like Red On A RoseAlan Jackson | 89 | Chart history → |
| 91 | The Diary Of JaneBreaking Benjamin | 91 | Chart history → |
| 92 | Nothing Left To LoseMat Kearney | 96 | Chart history → |
| 93 | Some People ChangeMontgomery Gentry | 97 | Chart history → |
| 94 | Remember The NameFort Minor Featuring Styles Of Beyond | 88 | Chart history → |
| 95 | Amarillo SkyJason Aldean | 100 | Chart history → |
| 96 | Love YouJack Ingram | 98 | Chart history → |
| 97 | Long Way 2 GoCassie | — | Chart history → |
| 98 | Canadian Idiot"Weird Al" Yankovic | 94 | Chart history → |
| 99 | Tu AmorRBD | — | Chart history → |
| 100 | Face DownThe Red Jumpsuit Apparatus | — | Chart history → |