| 1 | GlamorousFergie Featuring Ludacris | 1 | Chart history → |
| 2 | This Is Why I'm HotMims | 2 | Chart history → |
| 3 | Don't MatterAkon | 3 | Chart history → |
| 4 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 5 | Chart history → |
| 5 | The Sweet EscapeGwen Stefani Featuring Akon | 4 | Chart history → |
| 6 | Throw Some D'sRich Boy Featuring Polow Da Don | 27 | Chart history → |
| 7 | It's Not OverDaughtry | 7 | Chart history → |
| 8 | GirlfriendAvril Lavigne | 9 | Chart history → |
| 9 | What Goes Around...Comes AroundJustin Timberlake | 8 | Chart history → |
| 10 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 6 | Chart history → |
| 11 | Say It RightNelly Furtado | 10 | Listen & explore → |
| 12 | YouLloyd Featuring Lil Wayne | 16 | Chart history → |
| 13 | Ice BoxOmarion | 12 | Chart history → |
| 14 | Lost Without URobin Thicke | 15 | Chart history → |
| 15 | Last NightDiddy Featuring Keyshia Cole | 17 | Chart history → |
| 16 | IrreplaceableBeyonce | 14 | Chart history → |
| 17 | If Everyone CaredNickelback | 18 | Chart history → |
| 18 | Make It RainFat Joe Featuring Lil Wayne | 20 | Chart history → |
| 19 | Runaway LoveLudacris Featuring Mary J. Blige | 11 | Chart history → |
| 20 | I'm A FlirtR. Kelly Or Bow Wow (Featuring T.I. & T-Pain) | 41 | Chart history → |
| 21 | Break It OffRihanna & Sean Paul | 13 | Chart history → |
| 22 | Walk It OutUnk | 19 | Chart history → |
| 23 | Go GettaYoung Jeezy Featuring R. Kelly | 24 | Chart history → |
| 24 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 29 | Chart history → |
| 25 | CandymanChristina Aguilera | 31 | Chart history → |
| 26 | Face DownThe Red Jumpsuit Apparatus | 30 | Chart history → |
| 27 | We Fly HighJim Jones | 25 | Chart history → |
| 28 | How To Save A LifeThe Fray | 23 | Chart history → |
| 29 | U + Ur HandP!nk | 36 | Chart history → |
| 30 | Before He CheatsCarrie Underwood | 28 | Chart history → |
| 31 | On The HotlinePretty Ricky | 21 | Chart history → |
| 32 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 46 | Chart history → |
| 33 | I Wanna Love YouAkon Featuring Snoop Dogg | 22 | Chart history → |
| 34 | Waiting On The World To ChangeJohn Mayer | 26 | Chart history → |
| 35 | 2 StepUnk | 43 | Chart history → |
| 36 | FergaliciousFergie | 34 | Chart history → |
| 37 | Smack ThatAkon Featuring Eminem | 33 | Chart history → |
| 38 | BuddyMusiq Soulchild | 52 | Chart history → |
| 39 | Keep Holding OnAvril Lavigne | 32 | Chart history → |
| 40 | Chasing CarsSnow Patrol | 37 | Chart history → |
| 41 | WastedCarrie Underwood | 45 | Chart history → |
| 42 | With LoveHilary Duff | — | Chart history → |
| 43 | My LoveJustin Timberlake Featuring T.I. | 35 | Chart history → |
| 44 | Like A BoyCiara | 61 | Chart history → |
| 45 | She's Like The WindLumidee Featuring Tony Sunshine | 50 | Chart history → |
| 46 | BostonAugustana | 40 | Chart history → |
| 47 | Here (In Your Arms)Hellogoodbye | 39 | Chart history → |
| 48 | HomeDaughtry | 58 | Chart history → |
| 49 | Over ItKatharine McPhee | 51 | Chart history → |
| 50 | Top BackT.I. | 48 | Chart history → |
| 51 | Snow ((Hey Oh))Red Hot Chili Peppers | 38 | Chart history → |
| 52 | Stupid BoyKeith Urban | 49 | Chart history → |
| 53 | Pop, Lock & Drop ItHuey | 69 | Chart history → |
| 54 | Outta My SystemBow Wow Featuring T-Pain & Johnta Austin | 65 | Chart history → |
| 55 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | 59 | Chart history → |
| 56 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | 63 | Chart history → |
| 57 | Poppin'Chris Brown Featuring Jay Biz | 53 | Chart history → |
| 58 | Into The OceanBlue October | 57 | Chart history → |
| 59 | PainThree Days Grace | 56 | Chart history → |
| 60 | AnywayMartina McBride | 62 | Chart history → |
| 61 | Look After YouThe Fray | 78 | Chart history → |
| 62 | PromiseCiara | 55 | Chart history → |
| 63 | Beer In MexicoKenny Chesney | 66 | Chart history → |
| 64 | Wouldn't Get FarThe Game Featuring Kanye West | 68 | Chart history → |
| 65 | Settlin'Sugarland | 70 | Chart history → |
| 66 | Watching YouRodney Atkins | 60 | Chart history → |
| 67 | Because Of YouNe-Yo | 76 | Chart history → |
| 68 | SurvivalismNine Inch Nails | — | Chart history → |
| 69 | Year 3000Jonas Brothers | 54 | Chart history → |
| 70 | Ladies Love Country BoysTrace Adkins | 67 | Chart history → |
| 71 | StandRascal Flatts | 72 | Chart history → |
| 72 | Better Than MeHinder | 79 | Chart history → |
| 73 | FlatheadThe Fratellis | 74 | Chart history → |
| 74 | Read My MindThe Killers | 80 | Chart history → |
| 75 | I'll Wait For YouJoe Nichols | 77 | Chart history → |
| 76 | Get It ShawtyLloyd | — | Chart history → |
| 77 | Teardrops On My GuitarTaylor Swift | 93 | Chart history → |
| 78 | High Maintenance WomanToby Keith | 81 | Chart history → |
| 79 | FidelityRegina Spektor | 73 | Chart history → |
| 80 | Long Trip AloneDierks Bentley | 85 | Chart history → |
| 81 | Last Dollar (Fly Away)Tim McGraw | 84 | Chart history → |
| 82 | King KongJibbs Featuring Chamillionaire | 71 | Chart history → |
| 83 | SmileLily Allen | 88 | Chart history → |
| 84 | And I Am Telling You I'm Not GoingJennifer Hudson | 75 | Chart history → |
| 85 | Grace KellyMIKA | 97 | Chart history → |
| 86 | Hillbilly DeluxeBrooks & Dunn | 86 | Chart history → |
| 87 | 1st TimeYung Joc Featuring Marques Houston & Trey Songz | 82 | Chart history → |
| 88 | Good DirectionsBilly Currington | 91 | Chart history → |
| 89 | The RiverGood Charlotte Featuring M. Shadows And Synyster Gates | — | Chart history → |
| 90 | You Know I'm No GoodAmy Winehouse | — | Chart history → |
| 91 | RehabAmy Winehouse | — | Chart history → |
| 92 | CircleMarques Houston | 83 | Chart history → |
| 93 | Upgrade UBeyonce Featuring Jay Z | 98 | Chart history → |
| 94 | Beautiful LiarBeyonce & Shakira | — | Chart history → |
| 95 | Please Don't GoTank | 95 | Chart history → |
| 96 | Like ThisKelly Rowland Featuring Eve | — | Chart history → |
| 97 | DashboardModest Mouse | 94 | Chart history → |
| 98 | Doe Boy FreshThree 6 Mafia Featuring Chamillionaire | — | Chart history → |
| 99 | From Yesterday30 Seconds To Mars | 99 | Chart history → |
| 100 | Alyssa LiesJason Michael Carroll | 87 | Chart history → |