| 1 | Makes Me WonderMaroon 5 | 1 | Chart history → |
| 2 | Because Of YouNe-Yo | 5 | Chart history → |
| 3 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 4 | Chart history → |
| 4 | GirlfriendAvril Lavigne | 2 | Chart history → |
| 5 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | 3 | Chart history → |
| 6 | I'll Stand By YouCarrie Underwood | 6 | Chart history → |
| 7 | GlamorousFergie Featuring Ludacris | 7 | Chart history → |
| 8 | Don't MatterAkon | 9 | Chart history → |
| 9 | I TriedBone Thugs-N-Harmony Featuring Akon | 11 | Chart history → |
| 10 | The Sweet EscapeGwen Stefani Featuring Akon | 10 | Chart history → |
| 11 | Pop, Lock & Drop ItHuey | 12 | Chart history → |
| 12 | Never AgainKelly Clarkson | 8 | Chart history → |
| 13 | Last NightDiddy Featuring Keyshia Cole | 13 | Chart history → |
| 14 | Before He CheatsCarrie Underwood | 14 | Chart history → |
| 15 | I'm A FlirtR. Kelly Or Bow Wow (Featuring T.I. & T-Pain) | 18 | Chart history → |
| 16 | U + Ur HandP!nk | 16 | Chart history → |
| 17 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 15 | Chart history → |
| 18 | Summer LoveJustin Timberlake | 22 | Chart history → |
| 19 | HomeDaughtry | 21 | Chart history → |
| 20 | This Is Why I'm HotMims | 17 | Chart history → |
| 21 | Like A BoyCiara | 20 | Chart history → |
| 22 | Get It ShawtyLloyd | 24 | Chart history → |
| 23 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 23 | Chart history → |
| 24 | Beautiful LiarBeyonce & Shakira | 19 | Chart history → |
| 25 | Outta My SystemBow Wow Featuring T-Pain & Johnta Austin | 31 | Chart history → |
| 26 | Icky ThumpThe White Stripes | 28 | Chart history → |
| 27 | (You Want To) Make A MemoryBon Jovi | — | Chart history → |
| 28 | What I've DoneLinkin Park | 25 | Chart history → |
| 29 | Lost Without URobin Thicke | 27 | Chart history → |
| 30 | If Everyone CaredNickelback | 26 | Chart history → |
| 31 | It's Not OverDaughtry | 29 | Chart history → |
| 32 | Face DownThe Red Jumpsuit Apparatus | 32 | Chart history → |
| 33 | Say It RightNelly Furtado | 30 | Listen & explore → |
| 34 | 2 StepUnk | 34 | Chart history → |
| 35 | We Takin' OverDJ Khaled Featuring T.I., Akon, Rick Ross, Fat Joe, Lil' Wayne & Baby | 38 | Chart history → |
| 36 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | 36 | Chart history → |
| 37 | What Goes Around...Comes AroundJustin Timberlake | 33 | Chart history → |
| 38 | Thnks Fr Th MmrsFall Out Boy | 41 | Chart history → |
| 39 | Better Than MeHinder | 37 | Chart history → |
| 40 | Go GettaYoung Jeezy Featuring R. Kelly | 35 | Chart history → |
| 41 | Hey There DelilahPlain White T's | 44 | Chart history → |
| 42 | How To Save A LifeThe Fray | 39 | Chart history → |
| 43 | IrreplaceableBeyonce | 42 | Chart history → |
| 44 | StolenDashboard Confessional | 61 | Chart history → |
| 45 | Walk It OutUnk | 43 | Chart history → |
| 46 | WastedCarrie Underwood | 40 | Chart history → |
| 47 | Good DirectionsBilly Currington | 49 | Chart history → |
| 48 | TicksBrad Paisley | 48 | Chart history → |
| 49 | StandRascal Flatts | 46 | Chart history → |
| 50 | Teardrops On My GuitarTaylor Swift | 53 | Chart history → |
| 51 | Big Girls Don't CryFergie | 50 | Chart history → |
| 52 | UmbrellaRihanna Featuring Jay-Z | 63 | Chart history → |
| 53 | Working Class HeroGreen Day | — | Chart history → |
| 54 | Settlin'Sugarland | 54 | Chart history → |
| 55 | BuddyMusiq Soulchild | 51 | Chart history → |
| 56 | ForeverPapa Roach | 55 | Chart history → |
| 57 | Last Dollar (Fly Away)Tim McGraw | 47 | Chart history → |
| 58 | Over ItKatharine McPhee | 52 | Chart history → |
| 59 | Like ThisKelly Rowland Featuring Eve | 62 | Chart history → |
| 60 | Little WondersRob Thomas | 60 | Chart history → |
| 61 | Party Like A RockstarShop Boyz | 67 | Chart history → |
| 62 | MomentsEmerson Drive | 66 | Chart history → |
| 63 | Lost In This MomentBig & Rich | 69 | Chart history → |
| 64 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 57 | Chart history → |
| 65 | CandymanChristina Aguilera | 64 | Chart history → |
| 66 | Up To The MountainKelly Clarkson Featuring Jeff Beck | 56 | Chart history → |
| 67 | Please Don't GoTank | 72 | Chart history → |
| 68 | AnywayMartina McBride | 58 | Chart history → |
| 69 | When I See UFantasia | 75 | Chart history → |
| 70 | High Maintenance WomanToby Keith | 68 | Chart history → |
| 71 | Find Out Who Your Friends AreTracy Lawrence | 76 | Chart history → |
| 72 | With LoveHilary Duff | 59 | Chart history → |
| 73 | A Woman's LoveAlan Jackson | 74 | Chart history → |
| 74 | Read My MindThe Killers | 73 | Chart history → |
| 75 | Long Trip AloneDierks Bentley | 70 | Chart history → |
| 76 | You Raise Me UpJosh Groban & The African Children's Choir | 78 | Chart history → |
| 77 | Do It Just Like A RockstarFreak Nasty Featuring Crazy Mike | — | Chart history → |
| 78 | Doe Boy FreshThree 6 Mafia Featuring Chamillionaire | 71 | Chart history → |
| 79 | Don't Make MeBlake Shelton | 90 | Chart history → |
| 80 | Lucky ManMontgomery Gentry | 86 | Chart history → |
| 81 | A Different WorldBucky Covington | 80 | Chart history → |
| 82 | Signal FireSnow Patrol | 65 | Chart history → |
| 83 | Sexy LadyYung Berg Featuring Junior | 99 | Chart history → |
| 84 | Beer In MexicoKenny Chesney | 79 | Chart history → |
| 85 | EverythingMichael Buble | — | Chart history → |
| 86 | You Know I'm No GoodAmy Winehouse | 82 | Chart history → |
| 87 | Johnny CashJason Aldean | 92 | Chart history → |
| 88 | WrappedGeorge Strait | 88 | Chart history → |
| 89 | Grace KellyMIKA | 81 | Chart history → |
| 90 | I'm ThrowedPaul Wall Featuring Jermaine Dupri | 89 | Chart history → |
| 91 | BreathBreaking Benjamin | 87 | Chart history → |
| 92 | She's Like The WindLumidee Featuring Tony Sunshine | 77 | Chart history → |
| 93 | Lean Like A CholoDown A.K.A. Kilo | — | Chart history → |
| 94 | DigIncubus | 94 | Chart history → |
| 95 | SmileLily Allen | 95 | Chart history → |
| 96 | GravityJohn Mayer | 97 | Chart history → |
| 97 | If I Was Your ManJoe | 84 | Chart history → |
| 98 | On The HotlinePretty Ricky | 85 | Chart history → |
| 99 | Look After YouThe Fray | 83 | Chart history → |
| 100 | Wait For YouElliott Yamin | — | Chart history → |