| 1 | Makes Me WonderMaroon 5 | 2 | Chart history → |
| 2 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 1 | Chart history → |
| 3 | GirlfriendAvril Lavigne | 3 | Chart history → |
| 4 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | 4 | Chart history → |
| 5 | HomeDaughtry | 13 | Chart history → |
| 6 | Pop, Lock & Drop ItHuey | 7 | Chart history → |
| 7 | I TriedBone Thugs-N-Harmony Featuring Akon | 6 | Chart history → |
| 8 | Before He CheatsCarrie Underwood | 11 | Chart history → |
| 9 | Summer LoveJustin Timberlake | 14 | Chart history → |
| 10 | GlamorousFergie Featuring Ludacris | 8 | Chart history → |
| 11 | U + Ur HandP!nk | 10 | Chart history → |
| 12 | What I've DoneLinkin Park | 23 | Chart history → |
| 13 | Because Of YouNe-Yo | 5 | Chart history → |
| 14 | Thnks Fr Th MmrsFall Out Boy | 24 | Chart history → |
| 15 | I'm A FlirtR. Kelly Or Bow Wow (Featuring T.I. & T-Pain) | 16 | Chart history → |
| 16 | The Sweet EscapeGwen Stefani Featuring Akon | 12 | Chart history → |
| 17 | Never AgainKelly Clarkson | 15 | Chart history → |
| 18 | Don't MatterAkon | 9 | Chart history → |
| 19 | Last NightDiddy Featuring Keyshia Cole | 17 | Chart history → |
| 20 | Get It ShawtyLloyd | 18 | Chart history → |
| 21 | Big Girls Don't CryFergie | 41 | Chart history → |
| 22 | Like A BoyCiara | 19 | Chart history → |
| 23 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 21 | Chart history → |
| 24 | Outta My SystemBow Wow Featuring T-Pain & Johnta Austin | 22 | Chart history → |
| 25 | This Is Why I'm HotMims | 25 | Chart history → |
| 26 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 26 | Chart history → |
| 27 | Hey There DelilahPlain White T's | 37 | Chart history → |
| 28 | We Takin' OverDJ Khaled Featuring T.I., Akon, Rick Ross, Fat Joe, Lil' Wayne & Baby | 30 | Chart history → |
| 29 | It's Not OverDaughtry | 29 | Chart history → |
| 30 | If Everyone CaredNickelback | 28 | Chart history → |
| 31 | Wait For YouElliott Yamin | 80 | Chart history → |
| 32 | Face DownThe Red Jumpsuit Apparatus | 31 | Chart history → |
| 33 | Do You Know? (The Ping Pong Song)/DimeloEnrique Iglesias | — | Chart history → |
| 34 | Better Than MeHinder | 36 | Chart history → |
| 35 | 2 StepUnk | 33 | Chart history → |
| 36 | Beautiful LiarBeyonce & Shakira | 27 | Chart history → |
| 37 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | 38 | Chart history → |
| 38 | I'll Stand By YouCarrie Underwood | 20 | Chart history → |
| 39 | Say It RightNelly Furtado | 35 | Listen & explore → |
| 40 | Lost Without URobin Thicke | 34 | Chart history → |
| 41 | UmbrellaRihanna Featuring Jay-Z | 44 | Chart history → |
| 42 | Please Don't GoTank | 64 | Chart history → |
| 43 | TicksBrad Paisley | 46 | Chart history → |
| 44 | Teardrops On My GuitarTaylor Swift | 51 | Chart history → |
| 45 | Do It Just Like A RockstarFreak Nasty Featuring Crazy Mike | 56 | Chart history → |
| 46 | What Goes Around...Comes AroundJustin Timberlake | 40 | Chart history → |
| 47 | Good DirectionsBilly Currington | 42 | Chart history → |
| 48 | How To Save A LifeThe Fray | 43 | Chart history → |
| 49 | Lost In This MomentBig & Rich | 63 | Chart history → |
| 50 | AnonymousBobby Valentino Featuring Timbaland | 52 | Chart history → |
| 51 | Party Like A RockstarShop Boyz | 54 | Chart history → |
| 52 | StolenDashboard Confessional | 45 | Chart history → |
| 53 | Like ThisKelly Rowland Featuring Eve | 53 | Chart history → |
| 54 | WastedCarrie Underwood | 55 | Chart history → |
| 55 | Lean Like A CholoDown A.K.A. Kilo | 69 | Chart history → |
| 56 | Go GettaYoung Jeezy Featuring R. Kelly | 47 | Chart history → |
| 57 | MomentsEmerson Drive | 59 | Chart history → |
| 58 | ForeverPapa Roach | 58 | Chart history → |
| 59 | Straight To The Bank50 Cent | 32 | Chart history → |
| 60 | StandRascal Flatts | 57 | Chart history → |
| 61 | Little WondersRob Thomas | 61 | Chart history → |
| 62 | When I See UFantasia | 71 | Chart history → |
| 63 | Find Out Who Your Friends AreTracy Lawrence | 67 | Chart history → |
| 64 | BuddyMusiq Soulchild | 60 | Chart history → |
| 65 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 68 | Chart history → |
| 66 | Settlin'Sugarland | 62 | Chart history → |
| 67 | High Maintenance WomanToby Keith | 70 | Chart history → |
| 68 | Sexy LadyYung Berg Featuring Junior | 77 | Chart history → |
| 69 | (You Want To) Make A MemoryBon Jovi | 39 | Chart history → |
| 70 | Wipe Me DownLil Boosie Featuring Foxx & Webbie | 96 | Chart history → |
| 71 | Last Dollar (Fly Away)Tim McGraw | 66 | Chart history → |
| 72 | RehabAmy Winehouse | — | Chart history → |
| 73 | A Woman's LoveAlan Jackson | 73 | Chart history → |
| 74 | First TimeLifehouse | 48 | Chart history → |
| 75 | Lucky ManMontgomery Gentry | 75 | Chart history → |
| 76 | Same GirlR. Kelly Duet With Usher | 79 | Chart history → |
| 77 | Icky ThumpThe White Stripes | 65 | Chart history → |
| 78 | ImpactoDaddy Yankee Featuring Fergie | 95 | Chart history → |
| 79 | WrappedGeorge Strait | 86 | Chart history → |
| 80 | CandymanChristina Aguilera | 74 | Chart history → |
| 81 | AnywayMartina McBride | 78 | Chart history → |
| 82 | Like ThisMims | 91 | Chart history → |
| 83 | I Don't Wanna StopOzzy Osbourne | 85 | Chart history → |
| 84 | TambourineEve | 72 | Chart history → |
| 85 | I Told You SoKeith Urban | 94 | Chart history → |
| 86 | Johnny CashJason Aldean | 90 | Chart history → |
| 87 | teachmeMusiq Soulchild | 92 | Chart history → |
| 88 | A Different WorldBucky Covington | 87 | Chart history → |
| 89 | Don't Make MeBlake Shelton | 82 | Chart history → |
| 90 | Get Me BodiedBeyonce | 98 | Chart history → |
| 91 | BubblyColbie Caillat | — | Chart history → |
| 92 | Over ItKatharine McPhee | 76 | Chart history → |
| 93 | I Need YouTim McGraw With Faith Hill | — | Chart history → |
| 94 | SmileLily Allen | — | Chart history → |
| 95 | You Know I'm No GoodAmy Winehouse | — | Chart history → |
| 96 | The Great EscapeBoys Like Girls | — | Chart history → |
| 97 | Bleed It OutLinkin Park | — | Chart history → |
| 98 | Beer In MexicoKenny Chesney | 93 | Chart history → |
| 99 | Given UpLinkin Park | — | Chart history → |
| 100 | Read My MindThe Killers | 84 | Chart history → |