| 1 | Crank That (Soulja Boy)Soulja Boy Tell'em | 2 | Chart history → |
| 2 | StrongerKanye West | 3 | Chart history → |
| 3 | Big Girls Don't CryFergie | 1 | Chart history → |
| 4 | The Way I AreTimbaland Featuring Keri Hilson | 4 | Listen & explore → |
| 5 | Beautiful GirlsSean Kingston | 5 | Chart history → |
| 6 | BartenderT-Pain Featuring Akon | 7 | Chart history → |
| 7 | Hey There DelilahPlain White T's | 6 | Chart history → |
| 8 | RockstarNickelback | 11 | Chart history → |
| 9 | Make Me BetterFabolous Featuring Ne-Yo | 8 | Chart history → |
| 10 | ShawtyPlies Featuring T-Pain | 9 | Chart history → |
| 11 | Let It GoKeyshia Cole Featuring Missy Elliott & Lil Kim | 12 | Chart history → |
| 12 | Who KnewP!nk | 16 | Chart history → |
| 13 | UmbrellaRihanna Featuring Jay-Z | 10 | Chart history → |
| 14 | Wait For YouElliott Yamin | 13 | Chart history → |
| 15 | BedJ. Holiday | 15 | Chart history → |
| 16 | A Bay BayHurricane Chris | 14 | Chart history → |
| 17 | So SmallCarrie Underwood | 93 | Chart history → |
| 18 | Me LoveSean Kingston | 17 | Chart history → |
| 19 | Sorry, Blame It On MeAkon | 20 | Chart history → |
| 20 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 21 | Chart history → |
| 21 | Shut Up And DriveRihanna | 22 | Chart history → |
| 22 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 19 | Chart history → |
| 23 | LoveStonedJustin Timberlake | 23 | Chart history → |
| 24 | The Great EscapeBoys Like Girls | 25 | Chart history → |
| 25 | When You're GoneAvril Lavigne | 24 | Chart history → |
| 26 | First TimeLifehouse | 29 | Chart history → |
| 27 | Makes Me WonderMaroon 5 | 28 | Chart history → |
| 28 | Before He CheatsCarrie Underwood | 30 | Chart history → |
| 29 | HomeDaughtry | 26 | Chart history → |
| 30 | Party Like A RockstarShop Boyz | 27 | Chart history → |
| 31 | I Got It From My Mamawill.i.am | 32 | Chart history → |
| 32 | Sexy LadyYung Berg Featuring Junior | 33 | Chart history → |
| 33 | CycloneBaby Bash Featuring T-Pain | 42 | Chart history → |
| 34 | You Know What It IsT.I. Featuring Wyclef Jean | 37 | Chart history → |
| 35 | The Sweet EscapeGwen Stefani Featuring Akon | 35 | Chart history → |
| 36 | Thnks Fr Th MmrsFall Out Boy | 38 | Chart history → |
| 37 | Whine UpKat DeLuna Featuring Elephant Man | 40 | Chart history → |
| 38 | BubblyColbie Caillat | 59 | Chart history → |
| 39 | Do YouNe-Yo | 36 | Chart history → |
| 40 | Can't Leave 'Em AloneCiara Featuring 50 Cent | 51 | Chart history → |
| 41 | S.O.S.Jonas Brothers | 18 | Chart history → |
| 42 | These Are My PeopleRodney Atkins | 45 | Chart history → |
| 43 | WadsyanameNelly | — | Chart history → |
| 44 | Over YouDaughtry | 62 | Chart history → |
| 45 | ParalyzerFinger Eleven | 54 | Chart history → |
| 46 | Never Wanted Nothing MoreKenny Chesney | 43 | Chart history → |
| 47 | What I've DoneLinkin Park | 39 | Chart history → |
| 48 | When I See UFantasia | 44 | Chart history → |
| 49 | If You're Reading ThisTim McGraw | 48 | Chart history → |
| 50 | Because Of YouReba McEntire Duet With Kelly Clarkson | 53 | Chart history → |
| 51 | OnlineBrad Paisley | 58 | Chart history → |
| 52 | Wake Up CallMaroon 5 | 63 | Chart history → |
| 53 | Potential Breakup SongAly & AJ | 41 | Chart history → |
| 54 | I Get Money50 Cent | 85 | Chart history → |
| 55 | Take Me ThereRascal Flatts | 69 | Chart history → |
| 56 | Love Me If You CanToby Keith | 68 | Chart history → |
| 57 | teachmeMusiq Soulchild | 56 | Chart history → |
| 58 | Big Things Poppin' (Do It)T.I. | 55 | Chart history → |
| 59 | Like ThisMims | 66 | Chart history → |
| 60 | Proud Of The House We BuiltBrooks & Dunn | 71 | Chart history → |
| 61 | All My Friends SayLuke Bryan | 72 | Chart history → |
| 62 | Can't Tell Me NothingKanye West | 79 | Listen & explore → |
| 63 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 77 | Chart history → |
| 64 | Bleed It OutLinkin Park | 78 | Chart history → |
| 65 | Lean Like A CholoDown A.K.A. Kilo | 73 | Chart history → |
| 66 | Same GirlR. Kelly Duet With Usher | 49 | Chart history → |
| 67 | EverythingMichael Buble | 64 | Chart history → |
| 68 | Everyday AmericaSugarland | 80 | Chart history → |
| 69 | The PretenderFoo Fighters | 82 | Chart history → |
| 70 | RehabAmy Winehouse | 61 | Chart history → |
| 71 | Misery BusinessParamore | 57 | Chart history → |
| 72 | Int'l Players Anthem (I Choose You)UGK Featuring OutKast | 74 | Chart history → |
| 73 | More Than A MemoryGarth Brooks | — | Chart history → |
| 74 | Free And Easy (Down The Road I Go)Dierks Bentley | 83 | Chart history → |
| 75 | ApologizeTimbaland Featuring OneRepublic | 96 | Chart history → |
| 76 | Hood FiggaGorilla Zoe | 86 | Chart history → |
| 77 | You Are The Music In MeZac Efron & Vanessa Anne Hudgens | 31 | Chart history → |
| 78 | Coffee ShopYung Joc Featuring Gorilla Zoe | — | Chart history → |
| 79 | Clothes Off!!Gym Class Heroes | 67 | Chart history → |
| 80 | EasyPaula DeAnda Featuring Bow Wow | 75 | Chart history → |
| 81 | Baby Don't GoFabolous Featuring Jermaine Dupri | — | Chart history → |
| 82 | Gotta Go My Own WayZac Efron & Vanessa Anne Hudgens | 34 | Chart history → |
| 83 | Never Too LateThree Days Grace | 100 | Chart history → |
| 84 | Do You Know? (The Ping Pong Song)/DimeloEnrique Iglesias | 94 | Chart history → |
| 85 | Cupid ShuffleCupid | 89 | Chart history → |
| 86 | What Time Is ItHigh School Musical 2 Cast | 52 | Chart history → |
| 87 | Hold OnJonas Brothers | 60 | Chart history → |
| 88 | TeenagersMy Chemical Romance | 87 | Chart history → |
| 89 | Get Me BodiedBeyonce | — | Chart history → |
| 90 | Money In The BankSwizz Beatz | — | Chart history → |
| 91 | I Need YouTim McGraw With Faith Hill | 81 | Chart history → |
| 92 | 4 In The MorningGwen Stefani | 90 | Chart history → |
| 93 | How Far We've Comematchbox twenty | — | Chart history → |
| 94 | TambourineEve | 99 | Chart history → |
| 95 | (You Want To) Make A MemoryBon Jovi | 97 | Chart history → |
| 96 | Livin' Our Love SongJason Michael Carroll | — | Chart history → |
| 97 | Bet On ItZac Efron | 46 | Chart history → |
| 98 | Hate That I Love YouRihanna Featuring Ne-Yo | — | Chart history → |
| 99 | A Different WorldBucky Covington | 88 | Chart history → |
| 100 | Wipe Me DownLil Boosie Featuring Foxx & Webbie | 91 | Chart history → |