| 1 | StrongerKanye West | 2 | Chart history → |
| 2 | Crank That (Soulja Boy)Soulja Boy Tell'em | 1 | Chart history → |
| 3 | The Way I AreTimbaland Featuring Keri Hilson | 4 | Listen & explore → |
| 4 | Big Girls Don't CryFergie | 3 | Chart history → |
| 5 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 19 | Chart history → |
| 6 | BedJ. Holiday | 11 | Chart history → |
| 7 | Let It GoKeyshia Cole Featuring Missy Elliott & Lil Kim | 10 | Chart history → |
| 8 | RockstarNickelback | 6 | Chart history → |
| 9 | Who KnewP!nk | 14 | Chart history → |
| 10 | ShawtyPlies Featuring T-Pain | 9 | Chart history → |
| 11 | BartenderT-Pain Featuring Akon | 5 | Chart history → |
| 12 | How Far We've Comematchbox twenty | 12 | Chart history → |
| 13 | Hey There DelilahPlain White T's | 7 | Chart history → |
| 14 | Good LifeKanye West Featuring T-Pain | — | Chart history → |
| 15 | No OneAlicia Keys | 71 | Chart history → |
| 16 | BubblyColbie Caillat | 21 | Chart history → |
| 17 | UmbrellaRihanna Featuring Jay-Z | 17 | Chart history → |
| 18 | LoveStonedJustin Timberlake | 20 | Chart history → |
| 19 | Make Me BetterFabolous Featuring Ne-Yo | 13 | Chart history → |
| 20 | I Get Money50 Cent | 45 | Chart history → |
| 21 | Beautiful GirlsSean Kingston | 8 | Chart history → |
| 22 | Wait For YouElliott Yamin | 18 | Chart history → |
| 23 | Wake Up CallMaroon 5 | 40 | Chart history → |
| 24 | Me LoveSean Kingston | 16 | Chart history → |
| 25 | A Bay BayHurricane Chris | 15 | Chart history → |
| 26 | The Great EscapeBoys Like Girls | 23 | Chart history → |
| 27 | CycloneBaby Bash Featuring T-Pain | 28 | Chart history → |
| 28 | Shut Up And DriveRihanna | 24 | Chart history → |
| 29 | When You're GoneAvril Lavigne | 26 | Chart history → |
| 30 | Don't BlinkKenny Chesney | 79 | Chart history → |
| 31 | Sorry, Blame It On MeAkon | 22 | Chart history → |
| 32 | First TimeLifehouse | 29 | Chart history → |
| 33 | ApologizeTimbaland Featuring OneRepublic | 52 | Chart history → |
| 34 | Makes Me WonderMaroon 5 | 30 | Chart history → |
| 35 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 27 | Chart history → |
| 36 | HomeDaughtry | 31 | Chart history → |
| 37 | Over YouDaughtry | 38 | Chart history → |
| 38 | You Know What It IsT.I. Featuring Wyclef Jean | 34 | Chart history → |
| 39 | Before He CheatsCarrie Underwood | 32 | Chart history → |
| 40 | Thnks Fr Th MmrsFall Out Boy | 37 | Chart history → |
| 41 | Can't Tell Me NothingKanye West | 57 | Listen & explore → |
| 42 | OnlineBrad Paisley | 44 | Chart history → |
| 43 | I Got It From My Mamawill.i.am | 33 | Chart history → |
| 44 | So SmallCarrie Underwood | 25 | Chart history → |
| 45 | ParalyzerFinger Eleven | 43 | Chart history → |
| 46 | Party Like A RockstarShop Boyz | 36 | Chart history → |
| 47 | The Sweet EscapeGwen Stefani Featuring Akon | 39 | Chart history → |
| 48 | If You're Reading ThisTim McGraw | 46 | Chart history → |
| 49 | Do YouNe-Yo | 41 | Chart history → |
| 50 | Never Wanted Nothing MoreKenny Chesney | 55 | Chart history → |
| 51 | Love Me If You CanToby Keith | 53 | Chart history → |
| 52 | Can't Leave 'Em AloneCiara Featuring 50 Cent | 42 | Chart history → |
| 53 | Bleed It OutLinkin Park | 65 | Chart history → |
| 54 | Hate That I Love YouRihanna Featuring Ne-Yo | 78 | Chart history → |
| 55 | Take Me ThereRascal Flatts | 56 | Chart history → |
| 56 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 58 | Chart history → |
| 57 | WadsyanameNelly | 50 | Chart history → |
| 58 | The PretenderFoo Fighters | 64 | Chart history → |
| 59 | All My Friends SayLuke Bryan | 63 | Chart history → |
| 60 | Proud Of The House We BuiltBrooks & Dunn | 61 | Chart history → |
| 61 | 1234Feist | — | Chart history → |
| 62 | Whine UpKat DeLuna Featuring Elephant Man | 54 | Chart history → |
| 63 | These Are My PeopleRodney Atkins | 48 | Chart history → |
| 64 | Because Of YouReba McEntire Duet With Kelly Clarkson | 51 | Chart history → |
| 65 | Hood FiggaGorilla Zoe | 72 | Chart history → |
| 66 | teachmeMusiq Soulchild | 59 | Chart history → |
| 67 | Potential Breakup SongAly & AJ | 60 | Chart history → |
| 68 | Baby Don't GoFabolous Featuring Jermaine Dupri | 68 | Chart history → |
| 69 | More Than A MemoryGarth Brooks | 74 | Chart history → |
| 70 | Free And Easy (Down The Road I Go)Dierks Bentley | 70 | Chart history → |
| 71 | EverythingMichael Buble | 73 | Chart history → |
| 72 | Lean Like A CholoDown A.K.A. Kilo | 66 | Chart history → |
| 73 | Misery BusinessParamore | 75 | Chart history → |
| 74 | Never Too LateThree Days Grace | 76 | Chart history → |
| 75 | Gimme MoreBritney Spears | 85 | Listen & explore → |
| 76 | S.O.S.Jonas Brothers | 62 | Chart history → |
| 77 | Big Things Poppin' (Do It)T.I. | 67 | Chart history → |
| 78 | Int'l Players Anthem (I Choose You)UGK Featuring OutKast | 81 | Chart history → |
| 79 | Livin' Our Love SongJason Michael Carroll | 84 | Chart history → |
| 80 | TeenagersMy Chemical Romance | 83 | Chart history → |
| 81 | Clothes Off!!Gym Class Heroes | 86 | Chart history → |
| 82 | Shawty Is A 10The-Dream | 93 | Chart history → |
| 83 | Like ThisMims | 69 | Chart history → |
| 84 | Money In The BankSwizz Beatz | 87 | Chart history → |
| 85 | I Don't Wanna Be In Love (Dance Floor Anthem)Good Charlotte | 88 | Chart history → |
| 86 | InconsolableBackstreet Boys | — | Chart history → |
| 87 | Cupid ShuffleCupid | 82 | Chart history → |
| 88 | Do ItNelly Furtado | — | Chart history → |
| 89 | FallClay Walker | 94 | Chart history → |
| 90 | How 'Bout Them CowgirlsGeorge Strait | 97 | Chart history → |
| 91 | Same GirlR. Kelly Duet With Usher | 80 | Chart history → |
| 92 | Get Me BodiedBeyonce | 89 | Chart history → |
| 93 | I'm So HoodDJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross & Plies | — | Chart history → |
| 94 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | — | Chart history → |
| 95 | My Drink N' My 2 StepCassidy Featuring Swizz Beatz | — | Chart history → |
| 96 | FirecrackerJosh Turner | — | Chart history → |
| 97 | Do You Know? (The Ping Pong Song)/DimeloEnrique Iglesias | 95 | Chart history → |
| 98 | (You Want To) Make A MemoryBon Jovi | 92 | Chart history → |
| 99 | Me EnamoraJuanes | — | Chart history → |
| 100 | Kiss KissChris Brown Featuring T-Pain | — | Chart history → |