| 1 | Crank That (Soulja Boy)Soulja Boy Tell'em | 1 | Chart history → |
| 2 | StrongerKanye West | 2 | Chart history → |
| 3 | Gimme MoreBritney Spears | 3 | Listen & explore → |
| 4 | ApologizeTimbaland Featuring OneRepublic | 6 | Chart history → |
| 5 | The Way I AreTimbaland Featuring Keri Hilson | 4 | Listen & explore → |
| 6 | BedJ. Holiday | 7 | Chart history → |
| 7 | BubblyColbie Caillat | 10 | Chart history → |
| 8 | No OneAlicia Keys | 12 | Chart history → |
| 9 | Big Girls Don't CryFergie | 5 | Chart history → |
| 10 | Good LifeKanye West Featuring T-Pain | 18 | Chart history → |
| 11 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 13 | Chart history → |
| 12 | RockstarNickelback | 11 | Chart history → |
| 13 | CycloneBaby Bash Featuring T-Pain | 17 | Chart history → |
| 14 | Who KnewP!nk | 14 | Chart history → |
| 15 | How Far We've Comematchbox twenty | 15 | Chart history → |
| 16 | Let It GoKeyshia Cole Featuring Missy Elliott & Lil Kim | 9 | Chart history → |
| 17 | ShawtyPlies Featuring T-Pain | 16 | Chart history → |
| 18 | Hate That I Love YouRihanna Featuring Ne-Yo | 26 | Chart history → |
| 19 | LoveStonedJustin Timberlake | 20 | Chart history → |
| 20 | Hey There DelilahPlain White T's | 22 | Chart history → |
| 21 | BartenderT-Pain Featuring Akon | 21 | Chart history → |
| 22 | Take Me ThereRascal Flatts | 19 | Chart history → |
| 23 | Wake Up CallMaroon 5 | 25 | Chart history → |
| 24 | Wait For YouElliott Yamin | 24 | Chart history → |
| 25 | Over YouDaughtry | 31 | Chart history → |
| 26 | UmbrellaRihanna Featuring Jay-Z | 23 | Chart history → |
| 27 | 1234Feist | 8 | Chart history → |
| 28 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 41 | Chart history → |
| 29 | The Great EscapeBoys Like Girls | 29 | Chart history → |
| 30 | Don't BlinkKenny Chesney | 34 | Chart history → |
| 31 | Baby Don't GoFabolous Featuring Jermaine Dupri | 46 | Chart history → |
| 32 | ParalyzerFinger Eleven | 40 | Chart history → |
| 33 | Beautiful GirlsSean Kingston | 27 | Chart history → |
| 34 | Make Me BetterFabolous Featuring Ne-Yo | 28 | Chart history → |
| 35 | Kiss KissChris Brown Featuring T-Pain | 55 | Chart history → |
| 36 | When You're GoneAvril Lavigne | 32 | Chart history → |
| 37 | The Way I AmIngrid Michaelson | 80 | Chart history → |
| 38 | Me LoveSean Kingston | 30 | Chart history → |
| 39 | HomeDaughtry | 36 | Chart history → |
| 40 | Duffle Bag BoyPlayaz Circle Featuring Lil Wayne | 48 | Chart history → |
| 41 | First TimeLifehouse | 35 | Chart history → |
| 42 | I Get Money50 Cent | 33 | Chart history → |
| 43 | OnlineBrad Paisley | 39 | Chart history → |
| 44 | Thnks Fr Th MmrsFall Out Boy | 47 | Chart history → |
| 45 | Hood FiggaGorilla Zoe | 53 | Chart history → |
| 46 | Before He CheatsCarrie Underwood | 44 | Chart history → |
| 47 | Shawty Is A 10The-Dream | 57 | Chart history → |
| 48 | Love Me If You CanToby Keith | 54 | Chart history → |
| 49 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 38 | Chart history → |
| 50 | Do It WellJennifer Lopez | 52 | Chart history → |
| 51 | So SmallCarrie Underwood | 49 | Chart history → |
| 52 | You Know What It IsT.I. Featuring Wyclef Jean | 42 | Chart history → |
| 53 | The PretenderFoo Fighters | 37 | Chart history → |
| 54 | A Bay BayHurricane Chris | 43 | Chart history → |
| 55 | Blue MagicJAY-Z | — | Chart history → |
| 56 | TattooJordin Sparks | 58 | Chart history → |
| 57 | If You're Reading ThisTim McGraw | 50 | Chart history → |
| 58 | Proud Of The House We BuiltBrooks & Dunn | 59 | Chart history → |
| 59 | Sorry, Blame It On MeAkon | 51 | Chart history → |
| 60 | Bleed It OutLinkin Park | 60 | Chart history → |
| 61 | I'm So HoodDJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross & Plies | 75 | Chart history → |
| 62 | Free And Easy (Down The Road I Go)Dierks Bentley | 61 | Chart history → |
| 63 | I Don't Wanna Be In Love (Dance Floor Anthem)Good Charlotte | 69 | Chart history → |
| 64 | Shut Up And DriveRihanna | 56 | Chart history → |
| 65 | Do YouNe-Yo | 63 | Chart history → |
| 66 | Whine UpKat DeLuna Featuring Elephant Man | 64 | Chart history → |
| 67 | Our SongTaylor Swift | 86 | Chart history → |
| 68 | More Than A MemoryGarth Brooks | 68 | Chart history → |
| 69 | My Drink N' My 2 StepCassidy Featuring Swizz Beatz | 77 | Chart history → |
| 70 | Misery BusinessParamore | 76 | Chart history → |
| 71 | Can't Help But WaitTrey Songz | 90 | Chart history → |
| 72 | Soulja GirlSoulja Boy Tell'em Featuring I-15 | — | Chart history → |
| 73 | TeenagersMy Chemical Romance | 73 | Chart history → |
| 74 | All My Friends SayLuke Bryan | 62 | Chart history → |
| 75 | Can't Leave 'Em AloneCiara Featuring 50 Cent | 65 | Chart history → |
| 76 | Livin' Our Love SongJason Michael Carroll | 78 | Chart history → |
| 77 | Never Too LateThree Days Grace | 71 | Chart history → |
| 78 | Freaky GurlGucci Mane | 87 | Chart history → |
| 79 | Can't Tell Me NothingKanye West | 72 | Listen & explore → |
| 80 | S.O.S.Jonas Brothers | 79 | Chart history → |
| 81 | How 'Bout Them CowgirlsGeorge Strait | 85 | Chart history → |
| 82 | FallClay Walker | 88 | Chart history → |
| 83 | WadsyanameNelly | 66 | Chart history → |
| 84 | FirecrackerJosh Turner | 89 | Chart history → |
| 85 | Never Wanted Nothing MoreKenny Chesney | 70 | Chart history → |
| 86 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | 92 | Chart history → |
| 87 | These Are My PeopleRodney Atkins | 83 | Chart history → |
| 88 | Potential Breakup SongAly & AJ | 82 | Chart history → |
| 89 | Because Of YouReba McEntire Duet With Kelly Clarkson | 74 | Chart history → |
| 90 | HypnotizedPlies Featuring Akon | 96 | Chart history → |
| 91 | Int'l Players Anthem (I Choose You)UGK Featuring OutKast | 84 | Chart history → |
| 92 | I Got It From My Mamawill.i.am | 67 | Chart history → |
| 93 | Nothin' Better To DoLeAnn Rimes | 97 | Chart history → |
| 94 | Famous In A Small TownMiranda Lambert | 93 | Chart history → |
| 95 | Shoulda Let You GoKeyshia Cole Introducing Amina | 91 | Chart history → |
| 96 | Me EnamoraJuanes | 94 | Chart history → |
| 97 | Into The NightSantana Featuring Chad Kroeger | — | Chart history → |
| 98 | EverybodyKeith Urban | — | Chart history → |
| 99 | What Do Ya Think About ThatMontgomery Gentry | — | Chart history → |
| 100 | 1973James Blunt | 81 | Chart history → |