| 1 | Crank That (Soulja Boy)Soulja Boy Tell'em | 1 | Chart history → |
| 2 | Kiss KissChris Brown Featuring T-Pain | 22 | Chart history → |
| 3 | ApologizeTimbaland Featuring OneRepublic | 3 | Chart history → |
| 4 | No OneAlicia Keys | 4 | Chart history → |
| 5 | BubblyColbie Caillat | 5 | Chart history → |
| 6 | StrongerKanye West | 2 | Chart history → |
| 7 | CycloneBaby Bash Featuring T-Pain | 11 | Chart history → |
| 8 | Good LifeKanye West Featuring T-Pain | 10 | Chart history → |
| 9 | Hate That I Love YouRihanna Featuring Ne-Yo | 15 | Chart history → |
| 10 | The Way I AreTimbaland Featuring Keri Hilson | 7 | Listen & explore → |
| 11 | BedJ. Holiday | 8 | Chart history → |
| 12 | Big Girls Don't CryFergie | 9 | Chart history → |
| 13 | Gimme MoreBritney Spears | 6 | Listen & explore → |
| 14 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 12 | Chart history → |
| 15 | Who KnewP!nk | 14 | Chart history → |
| 16 | How Far We've Comematchbox twenty | 17 | Chart history → |
| 17 | RockstarNickelback | 13 | Chart history → |
| 18 | Let It GoKeyshia Cole Featuring Missy Elliott & Lil Kim | 16 | Chart history → |
| 19 | Wake Up CallMaroon 5 | 19 | Chart history → |
| 20 | Over YouDaughtry | 23 | Chart history → |
| 21 | ParalyzerFinger Eleven | 26 | Chart history → |
| 22 | ShawtyPlies Featuring T-Pain | 18 | Chart history → |
| 23 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 24 | Chart history → |
| 24 | Shawty Is A 10The-Dream | 33 | Chart history → |
| 25 | Baby Don't GoFabolous Featuring Jermaine Dupri | 27 | Chart history → |
| 26 | Hey There DelilahPlain White T's | 20 | Chart history → |
| 27 | Duffle Bag BoyPlayaz Circle Featuring Lil Wayne | 35 | Chart history → |
| 28 | LoveStonedJustin Timberlake | 21 | Chart history → |
| 29 | Wait For YouElliott Yamin | 25 | Chart history → |
| 30 | Don't BlinkKenny Chesney | 29 | Chart history → |
| 31 | I'm So HoodDJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross & Plies | 40 | Chart history → |
| 32 | UmbrellaRihanna Featuring Jay-Z | 30 | Chart history → |
| 33 | BartenderT-Pain Featuring Akon | 28 | Chart history → |
| 34 | First TimeLifehouse | 37 | Chart history → |
| 35 | The Great EscapeBoys Like Girls | 32 | Chart history → |
| 36 | So SmallCarrie Underwood | 36 | Chart history → |
| 37 | HomeDaughtry | 39 | Chart history → |
| 38 | Hood FiggaGorilla Zoe | 41 | Chart history → |
| 39 | TattooJordin Sparks | 55 | Chart history → |
| 40 | Before He CheatsCarrie Underwood | 42 | Chart history → |
| 41 | If You're Reading ThisTim McGraw | 46 | Chart history → |
| 42 | Take Me ThereRascal Flatts | 34 | Chart history → |
| 43 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 43 | Chart history → |
| 44 | Soulja GirlSoulja Boy Tell'em Featuring I-15 | 58 | Chart history → |
| 45 | ClumsyFergie | 91 | Chart history → |
| 46 | Our SongTaylor Swift | 56 | Chart history → |
| 47 | Can't Help But WaitTrey Songz | 60 | Chart history → |
| 48 | Thnks Fr Th MmrsFall Out Boy | 45 | Chart history → |
| 49 | Free And Easy (Down The Road I Go)Dierks Bentley | 59 | Chart history → |
| 50 | Beautiful GirlsSean Kingston | 38 | Chart history → |
| 51 | Do It WellJennifer Lopez | 31 | Chart history → |
| 52 | The PretenderFoo Fighters | 48 | Chart history → |
| 53 | I Don't Wanna Be In Love (Dance Floor Anthem)Good Charlotte | 62 | Chart history → |
| 54 | Into The NightSantana Featuring Chad Kroeger | 80 | Chart history → |
| 55 | My Drink N' My 2 StepCassidy Featuring Swizz Beatz | 63 | Chart history → |
| 56 | When You're GoneAvril Lavigne | 44 | Chart history → |
| 57 | OnlineBrad Paisley | 49 | Chart history → |
| 58 | Love Me If You CanToby Keith | 50 | Chart history → |
| 59 | Misery BusinessParamore | 67 | Chart history → |
| 60 | Me LoveSean Kingston | 52 | Chart history → |
| 61 | HypnotizedPlies Featuring Akon | 84 | Chart history → |
| 62 | As IfSara Evans | 74 | Chart history → |
| 63 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | 78 | Chart history → |
| 64 | A Bay BayHurricane Chris | 61 | Chart history → |
| 65 | More Than A MemoryGarth Brooks | 68 | Chart history → |
| 66 | Bleed It OutLinkin Park | 64 | Chart history → |
| 67 | You Know What It IsT.I. Featuring Wyclef Jean | 57 | Chart history → |
| 68 | ShadowplayThe Killers | — | Chart history → |
| 69 | I Get Money50 Cent | 53 | Chart history → |
| 70 | Livin' Our Love SongJason Michael Carroll | 69 | Chart history → |
| 71 | Freaky GurlGucci Mane | 71 | Chart history → |
| 72 | FallClay Walker | 70 | Chart history → |
| 73 | FirecrackerJosh Turner | 75 | Chart history → |
| 74 | How 'Bout Them CowgirlsGeorge Strait | 77 | Chart history → |
| 75 | Sorry, Blame It On MeAkon | 66 | Chart history → |
| 76 | 1234Feist | 51 | Chart history → |
| 77 | Shoulda Let You GoKeyshia Cole Introducing Amina | 82 | Chart history → |
| 78 | Shut Up And DriveRihanna | 72 | Chart history → |
| 79 | Never Too LateThree Days Grace | 81 | Chart history → |
| 80 | StaySugarland | 89 | Chart history → |
| 81 | TeenagersMy Chemical Romance | 76 | Chart history → |
| 82 | S.O.S.Jonas Brothers | 79 | Chart history → |
| 83 | Nothin' Better To DoLeAnn Rimes | 87 | Chart history → |
| 84 | Proud Of The House We BuiltBrooks & Dunn | 65 | Chart history → |
| 85 | Fake ItSeether | 92 | Chart history → |
| 86 | Can't Tell Me NothingKanye West | 85 | Listen & explore → |
| 87 | Me EnamoraJuanes | — | Chart history → |
| 88 | Pictures Of YouThe Last Goodnight | 95 | Chart history → |
| 89 | EverybodyKeith Urban | 99 | Chart history → |
| 90 | What Do Ya Think About ThatMontgomery Gentry | 100 | Chart history → |
| 91 | These Are My PeopleRodney Atkins | 93 | Chart history → |
| 92 | Never Wanted Nothing MoreKenny Chesney | 90 | Chart history → |
| 93 | Famous In A Small TownMiranda Lambert | 98 | Chart history → |
| 94 | Love Like ThisNatasha Bedingfield Featuring Sean Kingston | — | Chart history → |
| 95 | All My Friends SayLuke Bryan | 86 | Chart history → |
| 96 | The Hand ClapHurricane Chris Featuring Big Poppa | — | Chart history → |
| 97 | The Way I AmIngrid Michaelson | 54 | Chart history → |
| 98 | Ready, Set, Don't GoBilly Ray Cyrus With Miley Cyrus | 96 | Chart history → |
| 99 | Blue MagicJAY-Z | 88 | Chart history → |
| 100 | Just FineMary J. Blige | — | Chart history → |