| 1 | LowFlo Rida Featuring T-Pain | 1 | Chart history → |
| 2 | With YouChris Brown | 2 | Chart history → |
| 3 | Don't Stop The MusicRihanna | 3 | Listen & explore → |
| 4 | No OneAlicia Keys | 5 | Chart history → |
| 5 | ApologizeTimbaland Featuring OneRepublic | 4 | Chart history → |
| 6 | Love SongSara Bareilles | 6 | Chart history → |
| 7 | New SoulYael Naim | 9 | Chart history → |
| 8 | Sensual SeductionSnoop Dogg | 8 | Chart history → |
| 9 | Take You ThereSean Kingston | 10 | Chart history → |
| 10 | SorryBuckcherry | 11 | Chart history → |
| 11 | ClumsyFergie | 7 | Chart history → |
| 12 | See You AgainMiley Cyrus | 17 | Chart history → |
| 13 | IndependentWebbie Featuring Lil' Phat & Lil' Boosie | 13 | Chart history → |
| 14 | Like You'll Never See Me AgainAlicia Keys | 12 | Chart history → |
| 15 | Teardrops On My GuitarTaylor Swift | 15 | Chart history → |
| 16 | TattooJordin Sparks | 18 | Chart history → |
| 17 | BubblyColbie Caillat | 16 | Chart history → |
| 18 | SuffocateJ. Holiday | 22 | Chart history → |
| 19 | Shadow Of The DayLinkin Park | 20 | Chart history → |
| 20 | ParalyzerFinger Eleven | 19 | Chart history → |
| 21 | SuperstarLupe Fiasco Featuring Matthew Santos | 25 | Chart history → |
| 22 | Kiss KissChris Brown Featuring T-Pain | 14 | Chart history → |
| 23 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | 21 | Chart history → |
| 24 | I RememberKeyshia Cole | 26 | Chart history → |
| 25 | Piece Of MeBritney Spears | 23 | Chart history → |
| 26 | Love Like ThisNatasha Bedingfield Featuring Sean Kingston | 24 | Chart history → |
| 27 | HypnotizedPlies Featuring Akon | 32 | Chart history → |
| 28 | Into The NightSantana Featuring Chad Kroeger | 27 | Chart history → |
| 29 | Our SongTaylor Swift | 31 | Chart history → |
| 30 | Just FineMary J. Blige | 28 | Chart history → |
| 31 | Can't Help But WaitTrey Songz | 29 | Chart history → |
| 32 | No AirJordin Sparks Duet With Chris Brown | 42 | Chart history → |
| 33 | Stop And StareOneRepublic | 34 | Chart history → |
| 34 | Hate That I Love YouRihanna Featuring Ne-Yo | 30 | Chart history → |
| 35 | Big Girls Don't CryFergie | 36 | Chart history → |
| 36 | Flashing LightsKanye West Featuring Dwele | 33 | Listen & explore → |
| 37 | When You Look Me In The EyesJonas Brothers | 49 | Chart history → |
| 38 | Ready, Set, Don't GoBilly Ray Cyrus With Miley Cyrus | 37 | Chart history → |
| 39 | FalsettoThe-Dream | 51 | Chart history → |
| 40 | All-American GirlCarrie Underwood | 47 | Chart history → |
| 41 | Crying Out For MeMario | 46 | Chart history → |
| 42 | Crank That (Soulja Boy)Soulja Boy Tell'em | 35 | Chart history → |
| 43 | Letter To MeBrad Paisley | 40 | Chart history → |
| 44 | CycloneBaby Bash Featuring T-Pain | 38 | Chart history → |
| 45 | Watching AirplanesGary Allan | 44 | Chart history → |
| 46 | The Way I AreTimbaland Featuring Keri Hilson | 45 | Listen & explore → |
| 47 | Who KnewP!nk | 41 | Chart history → |
| 48 | Calabria 2008Enur Featuring Natasja | 53 | Chart history → |
| 49 | Misery BusinessParamore | 39 | Chart history → |
| 50 | Pop BottlesBirdman Featuring Lil Wayne | 43 | Chart history → |
| 51 | Cleaning This Gun (Come On In Boy)Rodney Atkins | 54 | Chart history → |
| 52 | Sexy Can IRay J & Yung Berg | 77 | Chart history → |
| 53 | Winner At A Losing GameRascal Flatts | 52 | Chart history → |
| 54 | Won't Go Home Without YouMaroon 5 | 48 | Chart history → |
| 55 | ShiftworkKenny Chesney Duet With George Strait | 59 | Chart history → |
| 56 | Dey KnowShawty Lo | 61 | Chart history → |
| 57 | What Is ItBaby Bash Featuring Sean Kingston | 60 | Chart history → |
| 58 | I Won't TellFat Joe Featuring J. Holiday | 57 | Chart history → |
| 59 | What Hurts The MostCascada | 58 | Chart history → |
| 60 | Feels Like TonightDaughtry | 69 | Chart history → |
| 61 | FeedbackJanet | 56 | Chart history → |
| 62 | StaySugarland | 55 | Chart history → |
| 63 | Small Town Southern ManAlan Jackson | 64 | Chart history → |
| 64 | Whatever It TakesLifehouse | 66 | Chart history → |
| 65 | Fake ItSeether | 62 | Chart history → |
| 66 | The AnthemPitbull Featuring Lil Jon | 72 | Chart history → |
| 67 | Stealing CinderellaChuck Wicks | 65 | Chart history → |
| 68 | International HarvesterCraig Morgan | 68 | Chart history → |
| 69 | The Way I AmIngrid Michaelson | 73 | Chart history → |
| 70 | Like WhoaAly & AJ | 63 | Chart history → |
| 71 | Get Buck In HereDJ Felli Fel Featuring Diddy, Akon, Ludacris & Lil Jon | 67 | Chart history → |
| 72 | Hero/HeroineBoys Like Girls | 70 | Chart history → |
| 73 | I'll Be WaitingLenny Kravitz | — | Chart history → |
| 74 | Ching-A-LingMissy Elliott | 83 | Chart history → |
| 75 | If I Had EyesJack Johnson | 71 | Chart history → |
| 76 | YAHHH!Soulja Boy Tell'em Featuring Arab | 86 | Chart history → |
| 77 | Love Is FreeSheryl Crow | — | Chart history → |
| 78 | crushcrushcrushParamore | 78 | Chart history → |
| 79 | What Do Ya Think About ThatMontgomery Gentry | 74 | Chart history → |
| 80 | Laughed Until We CriedJason Aldean | 84 | Chart history → |
| 81 | SayJohn Mayer | 90 | Chart history → |
| 82 | Rock StarHannah Montana | 81 | Chart history → |
| 83 | NeverJaheim | 82 | Chart history → |
| 84 | What Kinda GoneChris Cagle | 85 | Chart history → |
| 85 | You're Gonna Miss ThisTrace Adkins | 95 | Chart history → |
| 86 | RealizeColbie Caillat | — | Chart history → |
| 87 | GirlfriendBow Wow & Omarion | 75 | Chart history → |
| 88 | Umma Do MeRocko | — | Chart history → |
| 89 | God Must Be BusyBrooks & Dunn | 94 | Chart history → |
| 90 | Long Road To RuinFoo Fighters | 99 | Chart history → |
| 91 | SuspicionsTim McGraw | 87 | Chart history → |
| 92 | PsychoPuddle Of Mudd | 100 | Chart history → |
| 93 | Get My Drink OnToby Keith | 89 | Chart history → |
| 94 | Shoulda Let You GoKeyshia Cole Introducing Amina | 80 | Chart history → |
| 95 | Nine In The AfternoonPanic! At The Disco | 79 | Chart history → |
| 96 | Stronger WomanJewel | — | Chart history → |
| 97 | KillaCherish Featuring Yung Joc | — | Chart history → |
| 98 | Pictures Of YouThe Last Goodnight | 91 | Chart history → |
| 99 | Wanna Be Startin' Somethin' 2008Michael Jackson With Akon | 92 | Chart history → |
| 100 | EverybodyKeith Urban | 93 | Chart history → |