| 1 | Bleeding LoveLeona Lewis | 2 | Chart history → |
| 2 | LollipopLil Wayne Featuring Static Major | 1 | Chart history → |
| 3 | No AirJordin Sparks Duet With Chris Brown | 3 | Chart history → |
| 4 | 4 MinutesMadonna Featuring Justin Timberlake & Timbaland | 6 | Listen & explore → |
| 5 | Love In This ClubUsher Featuring Young Jeezy | 4 | Chart history → |
| 6 | Sexy Can IRay J & Yung Berg | 7 | Chart history → |
| 7 | Touch My BodyMariah Carey | 5 | Chart history → |
| 8 | Love SongSara Bareilles | 8 | Chart history → |
| 9 | ForeverChris Brown | — | Chart history → |
| 10 | With YouChris Brown | 9 | Chart history → |
| 11 | LowFlo Rida Featuring T-Pain | 11 | Chart history → |
| 12 | See You AgainMiley Cyrus | 10 | Chart history → |
| 13 | SayJohn Mayer | 12 | Chart history → |
| 14 | Leavin'Jesse McCartney | — | Chart history → |
| 15 | DamagedDanity Kane | 14 | Chart history → |
| 16 | Stop And StareOneRepublic | 15 | Chart history → |
| 17 | Don't Stop The MusicRihanna | 13 | Listen & explore → |
| 18 | The BossRick Ross Featuring T-Pain | 17 | Chart history → |
| 19 | Pocketful Of SunshineNatasha Bedingfield | 16 | Chart history → |
| 20 | What You GotColby O'Donis Featuring Akon | 31 | Chart history → |
| 21 | ApologizeTimbaland Featuring OneRepublic | 18 | Chart history → |
| 22 | SorryBuckcherry | 20 | Chart history → |
| 23 | Bust It Baby Part 2Plies Featuring Ne-Yo | 32 | Chart history → |
| 24 | No OneAlicia Keys | 21 | Chart history → |
| 25 | IndependentWebbie Featuring Lil' Phat & Lil' Boosie | 19 | Chart history → |
| 26 | RealizeColbie Caillat | 34 | Chart history → |
| 27 | You're Gonna Miss ThisTrace Adkins | 24 | Chart history → |
| 28 | She Got It2 Pistols Featuring T-Pain & Tay Dizm | 27 | Chart history → |
| 29 | Picture To BurnTaylor Swift | 29 | Chart history → |
| 30 | Just Got Started Lovin' YouJames Otto | 30 | Chart history → |
| 31 | Our SongTaylor Swift | 28 | Chart history → |
| 32 | Bye ByeMariah Carey | 23 | Chart history → |
| 33 | ElevatorFlo Rida Featuring Timbaland | 25 | Chart history → |
| 34 | Feels Like TonightDaughtry | 26 | Chart history → |
| 35 | Whatever It TakesLifehouse | 35 | Chart history → |
| 36 | SuperstarLupe Fiasco Featuring Matthew Santos | 22 | Chart history → |
| 37 | I Saw God TodayGeorge Strait | 33 | Chart history → |
| 38 | BubblyColbie Caillat | 36 | Chart history → |
| 39 | ParalyzerFinger Eleven | 37 | Chart history → |
| 40 | I'm Still A GuyBrad Paisley | 41 | Chart history → |
| 41 | It's Not My Time3 Doors Down | 48 | Chart history → |
| 42 | Party PeopleNelly Featuring Fergie | 40 | Chart history → |
| 43 | KillaCherish Featuring Yung Joc | 39 | Chart history → |
| 44 | The Way That I Love YouAshanti | 44 | Chart history → |
| 45 | Shake ItMetro Station | 55 | Chart history → |
| 46 | Break The IceBritney Spears | 46 | Chart history → |
| 47 | In Love With A GirlGavin DeGraw | 56 | Chart history → |
| 48 | Teardrops On My GuitarTaylor Swift | 38 | Chart history → |
| 49 | TattooJordin Sparks | 42 | Chart history → |
| 50 | Love Is A Beautiful ThingPhil Vassar | 63 | Chart history → |
| 51 | All Around MeFlyleaf | 64 | Chart history → |
| 52 | Every DayRascal Flatts | 61 | Chart history → |
| 53 | Love Don't Live HereLady Antebellum | 58 | Chart history → |
| 54 | All-American GirlCarrie Underwood | 51 | Chart history → |
| 55 | I RememberKeyshia Cole | 50 | Chart history → |
| 56 | Last NameCarrie Underwood | 65 | Chart history → |
| 57 | Won't Go Home Without YouMaroon 5 | 60 | Chart history → |
| 58 | When You Look Me In The EyesJonas Brothers | 53 | Chart history → |
| 59 | What Kinda GoneChris Cagle | 57 | Chart history → |
| 60 | A MilliLil Wayne | — | Chart history → |
| 61 | Shawty Get LooseLil Mama Featuring Chris Brown & T-Pain | 54 | Chart history → |
| 62 | Take A BowRihanna | 79 | Chart history → |
| 63 | FalsettoThe-Dream | 52 | Chart history → |
| 64 | Better As A MemoryKenny Chesney | 72 | Chart history → |
| 65 | Nine In The AfternoonPanic! At The Disco | 59 | Chart history → |
| 66 | Hollywood's Not AmericaFerras | 69 | Chart history → |
| 67 | HandlebarsFlobots | 77 | Chart history → |
| 68 | Dey KnowShawty Lo | 62 | Chart history → |
| 69 | CloserNe-Yo | 95 | Chart history → |
| 70 | New SoulYael Naim | 66 | Chart history → |
| 71 | PsychoPuddle Of Mudd | 70 | Chart history → |
| 72 | Boyfriend/GirlfriendC-Side Featuring Keyshia Cole | 88 | Chart history → |
| 73 | Small Town Southern ManAlan Jackson | 67 | Chart history → |
| 74 | The AnthemPitbull Featuring Lil Jon | 68 | Chart history → |
| 75 | HomeBlake Shelton | 83 | Chart history → |
| 76 | CustomerRaheem DeVaughn | 78 | Chart history → |
| 77 | Take You DownChris Brown | 99 | Chart history → |
| 78 | I'm YoursJason Mraz | 93 | Chart history → |
| 79 | Love In This Club Part IIUsher Featuring Beyonce & Lil Wayne | — | Chart history → |
| 80 | I Will Possess Your HeartDeath Cab For Cutie | 100 | Chart history → |
| 81 | Laughed Until We CriedJason Aldean | 71 | Chart history → |
| 82 | Inside The FireDisturbed | 73 | Chart history → |
| 83 | Back When I Knew It AllMontgomery Gentry | 84 | Chart history → |
| 84 | Pork And BeansWeezer | — | Chart history → |
| 85 | Trying To Stop Your LeavingDierks Bentley | 85 | Chart history → |
| 86 | She's A HottieToby Keith | 81 | Chart history → |
| 87 | MercyDuffy | — | Chart history → |
| 88 | Stronger WomanJewel | 87 | Chart history → |
| 89 | Last TimeTrey Songz | 86 | Chart history → |
| 90 | Beat ItFall Out Boy Featuring John Mayer | 80 | Chart history → |
| 91 | Te QuieroFlex | 90 | Chart history → |
| 92 | Get SillyV.I.C. | — | Chart history → |
| 93 | American BoyEstelle Featuring Kanye West | 98 | Listen & explore → |
| 94 | Rise Above ThisSeether | 97 | Chart history → |
| 95 | I Like The Way She Do ItG Unit | — | Chart history → |
| 96 | Little Miss ObsessiveAshlee Simpson With Tom Higgenson | — | Chart history → |
| 97 | I Luv Your GirlThe-Dream | — | Chart history → |
| 98 | We Weren't CrazyJosh Gracin | 96 | Chart history → |
| 99 | YAHHH!Soulja Boy Tell'em Featuring Arab | 75 | Chart history → |
| 100 | I Won't TellFat Joe Featuring J. Holiday | 76 | Chart history → |