| 1 | Whatever You LikeT.I. | 2 | Chart history → |
| 2 | Live Your LifeT.I. Featuring Rihanna | 3 | Chart history → |
| 3 | So WhatP!nk | 4 | Chart history → |
| 4 | WomanizerBritney Spears | 1 | Chart history → |
| 5 | Hot N ColdKaty Perry | 5 | Chart history → |
| 6 | DisturbiaRihanna | 6 | Chart history → |
| 7 | Let It RockKevin Rudolf Featuring Lil Wayne | 7 | Chart history → |
| 8 | Miss IndependentNe-Yo | 9 | Chart history → |
| 9 | FearlessTaylor Swift | — | Chart history → |
| 10 | Can't Believe ItT-Pain Featuring Lil Wayne | 8 | Chart history → |
| 11 | Better In TimeLeona Lewis | 11 | Chart history → |
| 12 | Love LockdownKanye West | 12 | Chart history → |
| 13 | I'm YoursJason Mraz | 15 | Chart history → |
| 14 | Love StoryTaylor Swift | 14 | Chart history → |
| 15 | Paper PlanesM.I.A. | 10 | Chart history → |
| 16 | CloserNe-Yo | 13 | Chart history → |
| 17 | Gotta Be SomebodyNickelback | 16 | Chart history → |
| 18 | Mrs. OfficerLil Wayne Featuring Bobby Valentino & Kidd Kidd | 18 | Chart history → |
| 19 | Right Now (Na Na Na)Akon | 26 | Chart history → |
| 20 | One Step At A TimeJordin Sparks | 19 | Chart history → |
| 21 | CrushDavid Archuleta | 22 | Chart history → |
| 22 | My LifeThe Game Featuring Lil Wayne | 23 | Chart history → |
| 23 | Got MoneyLil Wayne Featuring T-Pain | 21 | Chart history → |
| 24 | Fall For YouSecondhand Serenade | 25 | Chart history → |
| 25 | Viva La VidaColdplay | 24 | Listen & explore → |
| 26 | ForeverChris Brown | 20 | Chart history → |
| 27 | Keeps Gettin' BetterChristina Aguilera | 17 | Chart history → |
| 28 | SpotlightJennifer Hudson | 27 | Chart history → |
| 29 | In The AyerFlo Rida Featuring will.i.am | 29 | Chart history → |
| 30 | AddictedSaving Abel | 33 | Chart history → |
| 31 | American BoyEstelle Featuring Kanye West | 28 | Listen & explore → |
| 32 | Swagga Like UsJay-Z & T.I. Featuring Kanye West & Lil Wayne | 32 | Chart history → |
| 33 | What Them Girls LikeLudacris Co-Starring Chris Brown & Sean Garrett | 36 | Chart history → |
| 34 | DangerousKardinal Offishall Featuring Akon | 31 | Chart history → |
| 35 | KrazyPitbull Featuring Lil Jon | 30 | Chart history → |
| 36 | Chicken FriedZac Brown Band | 47 | Chart history → |
| 37 | Just A DreamCarrie Underwood | 37 | Chart history → |
| 38 | FreezeT-Pain Featuring Chris Brown | — | Chart history → |
| 39 | Love Remains The SameGavin Rossdale | 34 | Chart history → |
| 40 | Bleeding LoveLeona Lewis | 39 | Chart history → |
| 41 | T-ShirtShontelle | 44 | Chart history → |
| 42 | All Summer LongKid Rock | 35 | Chart history → |
| 43 | Everybody Wants To Go To HeavenKenny Chesney With The Wailers | 43 | Chart history → |
| 44 | Get Up50 Cent | — | Chart history → |
| 45 | Need U BadJazmine Sullivan | 38 | Chart history → |
| 46 | She Never Cried In Front Of MeToby Keith | 49 | Chart history → |
| 47 | Shake ItMetro Station | 41 | Chart history → |
| 48 | Don't Think I Don't Think About ItDarius Rucker | 42 | Chart history → |
| 49 | What About NowDaughtry | 48 | Chart history → |
| 50 | Shattered (Turn The Car Around)O.A.R. | 53 | Chart history → |
| 51 | So FlySlim Featuring Yung Joc | 54 | Chart history → |
| 52 | Green LightJohn Legend Featuring Andre 3000 | 58 | Chart history → |
| 53 | Put OnYoung Jeezy Featuring Kanye West | 51 | Chart history → |
| 54 | SwingSavage Featuring Soulja Boy Tell'em | 55 | Chart history → |
| 55 | I'm So PaidAkon Featuring Lil Wayne & Young Jeezy | 40 | Chart history → |
| 56 | Roll With MeMontgomery Gentry | 63 | Chart history → |
| 57 | All Summer LongThe Rock Heroes | 57 | Chart history → |
| 58 | HumanThe Killers | 52 | Chart history → |
| 59 | Just DanceLady Gaga Featuring Colby O'Donis | 60 | Chart history → |
| 60 | Let It GoTim McGraw | 64 | Chart history → |
| 61 | Already GoneSugarland | 71 | Chart history → |
| 62 | It's OverJesse McCartney | 68 | Chart history → |
| 63 | AngelNatasha Bedingfield | 67 | Chart history → |
| 64 | Right Here (Departed)Brandy | 69 | Chart history → |
| 65 | Waitin' On A WomanBrad Paisley | 59 | Chart history → |
| 66 | Start A BandBrad Paisley Duet With Keith Urban | — | Chart history → |
| 67 | Bust Your WindowsJazmine Sullivan | 81 | Chart history → |
| 68 | If I Were A BoyBeyonce | 100 | Chart history → |
| 69 | Do You Believe Me NowJimmy Wayne | 65 | Chart history → |
| 70 | Come On Get HigherMatt Nathanson | 72 | Chart history → |
| 71 | Bartender SongRehab | 70 | Chart history → |
| 72 | Single Ladies (Put A Ring On It)Beyonce | — | Chart history → |
| 73 | Body On MeNelly Featuring Ashanti & Akon | 61 | Chart history → |
| 74 | Country ManLuke Bryan | 78 | Chart history → |
| 75 | LovebugJonas Brothers | 86 | Chart history → |
| 76 | HereRascal Flatts | 83 | Chart history → |
| 77 | I'll WalkBucky Covington | 84 | Chart history → |
| 78 | Bad GirlfriendTheory Of A Deadman | 75 | Chart history → |
| 79 | You're Gonna Go Far, KidThe Offspring | 96 | Chart history → |
| 80 | I Don't CareFall Out Boy | 73 | Chart history → |
| 81 | In ColorJamey Johnson | 85 | Chart history → |
| 82 | Johnny & JuneHeidi Newfield | 62 | Chart history → |
| 83 | Lookin' For A Good TimeLady Antebellum | 91 | Chart history → |
| 84 | Chopped 'N' SkrewedT-Pain Featuring Ludacris | — | Chart history → |
| 85 | Cuddy BuddyMike Jones Featuring Trey Songz & Twista | — | Chart history → |
| 86 | All I Ever WantedChuck Wicks | 90 | Chart history → |
| 87 | Love RemembersCraig Morgan | — | Chart history → |
| 88 | Cry For YouSeptember | 79 | Chart history → |
| 89 | Feel That FireDierks Bentley | 82 | Chart history → |
| 90 | You Are The Best ThingRay LaMontagne | — | Chart history → |
| 91 | Be OKIngrid Michaelson | — | Chart history → |
| 92 | I Don't CareApocalyptica Featuring Adam Gontier | — | Chart history → |
| 93 | SuperwomanAlicia Keys | 87 | Chart history → |
| 94 | What A Catch, DonnieFall Out Boy | — | Chart history → |
| 95 | The Day That Never ComesMetallica | 88 | Chart history → |
| 96 | Pop ChampagneJim Jones & Ron Browz Featuring Juelz Santana | — | Chart history → |
| 97 | No Me Doy Por VencidoLuis Fonsi | 97 | Chart history → |
| 98 | TroubadourGeorge Strait | 77 | Chart history → |
| 99 | I Still Miss YouKeith Anderson | 92 | Chart history → |
| 100 | MagicRobin Thicke | 80 | Chart history → |