| 1 | Single Ladies (Put A Ring On It)Beyonce | 1 | Chart history → |
| 2 | Live Your LifeT.I. Featuring Rihanna | 2 | Chart history → |
| 3 | Just DanceLady Gaga Featuring Colby O'Donis | 3 | Chart history → |
| 4 | HeartlessKanye West | 7 | Listen & explore → |
| 5 | WomanizerBritney Spears | 6 | Chart history → |
| 6 | Hot N ColdKaty Perry | 8 | Chart history → |
| 7 | Love StoryTaylor Swift | 11 | Chart history → |
| 8 | Love LockdownKanye West | 10 | Chart history → |
| 9 | Whatever You LikeT.I. | 5 | Chart history → |
| 10 | If I Were A BoyBeyonce | 9 | Chart history → |
| 11 | CircusBritney Spears | 4 | Listen & explore → |
| 12 | I'm YoursJason Mraz | 12 | Chart history → |
| 13 | Let It RockKevin Rudolf Featuring Lil Wayne | 13 | Chart history → |
| 14 | Miss IndependentNe-Yo | 14 | Chart history → |
| 15 | Right Now (Na Na Na)Akon | 15 | Chart history → |
| 16 | So WhatP!nk | 16 | Chart history → |
| 17 | Gotta Be SomebodyNickelback | 17 | Chart history → |
| 18 | RehabRihanna | 21 | Chart history → |
| 19 | Gives You HellThe All-American Rejects | 37 | Chart history → |
| 20 | Chicken FriedZac Brown Band | 20 | Chart history → |
| 21 | Mrs. OfficerLil Wayne Featuring Bobby Valentino & Kidd Kidd | 19 | Chart history → |
| 22 | Pop ChampagneJim Jones & Ron Browz Featuring Juelz Santana | 25 | Chart history → |
| 23 | DisturbiaRihanna | 22 | Chart history → |
| 24 | Green LightJohn Legend Featuring Andre 3000 | 24 | Chart history → |
| 25 | One More DrinkLudacris Co-Starring T-Pain | 26 | Chart history → |
| 26 | AddictedSaving Abel | 23 | Chart history → |
| 27 | Can't Believe ItT-Pain Featuring Lil Wayne | 18 | Chart history → |
| 28 | Chopped 'N' SkrewedT-Pain Featuring Ludacris | 27 | Chart history → |
| 29 | You Found MeThe Fray | 30 | Chart history → |
| 30 | Better In TimeLeona Lewis | 28 | Chart history → |
| 31 | Put It On YaPlies Featuring Chris J | 65 | Chart history → |
| 32 | I Hate This PartThe Pussycat Dolls | 58 | Chart history → |
| 33 | I'm So PaidAkon Featuring Lil Wayne & Young Jeezy | 31 | Chart history → |
| 34 | SoberP!nk | 49 | Chart history → |
| 35 | UntouchedThe Veronicas | 40 | Chart history → |
| 36 | Viva La VidaColdplay | 32 | Listen & explore → |
| 37 | Shattered (Turn The Car Around)O.A.R. | 36 | Chart history → |
| 38 | Roll With MeMontgomery Gentry | 33 | Chart history → |
| 39 | I Don't CareFall Out Boy | 62 | Chart history → |
| 40 | Light OnDavid Cook | 48 | Chart history → |
| 41 | HumanThe Killers | 41 | Chart history → |
| 42 | CloserNe-Yo | 38 | Chart history → |
| 43 | Love Remains The SameGavin Rossdale | 35 | Chart history → |
| 44 | DecodeParamore | 46 | Chart history → |
| 45 | CrushDavid Archuleta | 43 | Chart history → |
| 46 | Fall For YouSecondhand Serenade | 44 | Chart history → |
| 47 | Trading PlacesUsher | 45 | Chart history → |
| 48 | White HorseTaylor Swift | 51 | Chart history → |
| 49 | Just Like MeJamie Foxx Featuring T.I. | 75 | Chart history → |
| 50 | Already GoneSugarland | 42 | Chart history → |
| 51 | Swagga Like UsJay-Z & T.I. Featuring Kanye West & Lil Wayne | 52 | Chart history → |
| 52 | In ColorJamey Johnson | 53 | Chart history → |
| 53 | Bust Your WindowsJazmine Sullivan | 39 | Chart history → |
| 54 | Feel That FireDierks Bentley | 56 | Chart history → |
| 55 | HereRascal Flatts | 50 | Chart history → |
| 56 | Cowgirls Don't CryBrooks & Dunn Featuring Reba McEntire | 60 | Chart history → |
| 57 | Country BoyAlan Jackson | 57 | Chart history → |
| 58 | She Wouldn't Be GoneBlake Shelton | 54 | Chart history → |
| 59 | Start A BandBrad Paisley Duet With Keith Urban | 55 | Chart history → |
| 60 | Right Here (Departed)Brandy | 34 | Chart history → |
| 61 | MadNe-Yo | 79 | Chart history → |
| 62 | Seventeen ForeverMetro Station | 82 | Chart history → |
| 63 | Playa Cardz RightKeyshia Cole Featuring 2Pac | 67 | Chart history → |
| 64 | Don'tBilly Currington | 63 | Chart history → |
| 65 | God Love HerToby Keith | 66 | Chart history → |
| 66 | Keeps Gettin' BetterChristina Aguilera | 59 | Chart history → |
| 67 | Lookin' For A Good TimeLady Antebellum | 70 | Chart history → |
| 68 | BeautifulAkon Featuring Colby O'Donis & Kardinal Offishall | 29 | Chart history → |
| 69 | Universal Mind ControlCommon Featuring Pharrell | 73 | Chart history → |
| 70 | Second ChanceShinedown | 76 | Chart history → |
| 71 | Sex On FireKings Of Leon | 72 | Listen & explore → |
| 72 | Just A DreamCarrie Underwood | 61 | Chart history → |
| 73 | She Got Her OwnNe-Yo Featuring Jamie Foxx & Fabolous | 93 | Chart history → |
| 74 | My LifeThe Game Featuring Lil Wayne | 64 | Chart history → |
| 75 | Sweet ThingKeith Urban | 74 | Chart history → |
| 76 | IfULeaveMusiq Soulchild Featuring Mary J. Blige | 71 | Chart history → |
| 77 | You're Gonna Go Far, KidThe Offspring | 77 | Chart history → |
| 78 | Come On Get HigherMatt Nathanson | 81 | Chart history → |
| 79 | Down The RoadKenny Chesney With Mac McAnally | 78 | Chart history → |
| 80 | I Don't CareApocalyptica Featuring Adam Gontier | 84 | Chart history → |
| 81 | RunLeona Lewis | — | Chart history → |
| 82 | Let It GoTim McGraw | 68 | Chart history → |
| 83 | Dead And GoneT.I. Featuring Justin Timberlake | 99 | Chart history → |
| 84 | KrazyPitbull Featuring Lil Jon | 83 | Chart history → |
| 85 | What About NowDaughtry | 85 | Chart history → |
| 86 | Arab MoneyBusta Rhymes Featuring Ron Browz | 86 | Chart history → |
| 87 | BrokenLifehouse | 89 | Chart history → |
| 88 | Without YouHinder | 90 | Chart history → |
| 89 | River Of LoveGeorge Strait | 87 | Chart history → |
| 90 | Turnin Me OnKeri Hilson Featuring Lil Wayne | — | Chart history → |
| 91 | Everybody Wants To Go To HeavenKenny Chesney With The Wailers | 88 | Chart history → |
| 92 | Poker FaceLady Gaga | — | Listen & explore → |
| 93 | When It HurtsAvant | 91 | Chart history → |
| 94 | Bad GirlfriendTheory Of A Deadman | 95 | Chart history → |
| 95 | Don't Trust Me3OH!3 | — | Chart history → |
| 96 | DivaBeyonce | — | Chart history → |
| 97 | BeepBobby V Featuring Yung Joc | — | Chart history → |
| 98 | Anything GoesRandy Houser | 92 | Chart history → |
| 99 | Rockin' That ThangThe-Dream | — | Chart history → |
| 100 | It Won't Be Like This For LongDarius Rucker | — | Chart history → |