| 1 | My Life Would Suck Without YouKelly Clarkson | 1 | Chart history → |
| 2 | Single Ladies (Put A Ring On It)Beyonce | 3 | Chart history → |
| 3 | HeartlessKanye West | 4 | Listen & explore → |
| 4 | Just DanceLady Gaga Featuring Colby O'Donis | 2 | Chart history → |
| 5 | Love StoryTaylor Swift | 5 | Chart history → |
| 6 | Gives You HellThe All-American Rejects | 6 | Chart history → |
| 7 | You Found MeThe Fray | 8 | Chart history → |
| 8 | Live Your LifeT.I. Featuring Rihanna | 7 | Chart history → |
| 9 | CircusBritney Spears | 9 | Listen & explore → |
| 10 | I'm YoursJason Mraz | 10 | Chart history → |
| 11 | Dead And GoneT.I. Featuring Justin Timberlake | 14 | Chart history → |
| 12 | I Hate This PartThe Pussycat Dolls | 11 | Chart history → |
| 13 | Let It RockKevin Rudolf Featuring Lil Wayne | 12 | Chart history → |
| 14 | Hot N ColdKaty Perry | 13 | Chart history → |
| 15 | MadNe-Yo | 19 | Chart history → |
| 16 | SoberP!nk | 16 | Chart history → |
| 17 | Prom QueenLil Wayne Featuring Shanell AKA SNL | — | Chart history → |
| 18 | WomanizerBritney Spears | 15 | Chart history → |
| 19 | Gotta Be SomebodyNickelback | 20 | Chart history → |
| 20 | UntouchedThe Veronicas | 17 | Chart history → |
| 21 | DivaBeyonce | 28 | Chart history → |
| 22 | Whatever You LikeT.I. | 18 | Chart history → |
| 23 | Poker FaceLady Gaga | 32 | Listen & explore → |
| 24 | Turnin Me OnKeri Hilson Featuring Lil Wayne | 35 | Chart history → |
| 25 | Love LockdownKanye West | 21 | Chart history → |
| 26 | So WhatP!nk | 23 | Chart history → |
| 27 | Right Now (Na Na Na)Akon | 22 | Chart history → |
| 28 | BeautifulAkon Featuring Colby O'Donis & Kardinal Offishall | 38 | Chart history → |
| 29 | Pop ChampagneJim Jones & Ron Browz Featuring Juelz Santana | 24 | Chart history → |
| 30 | Viva La VidaColdplay | 26 | Listen & explore → |
| 31 | Miss IndependentNe-Yo | 25 | Chart history → |
| 32 | Kiss Me Thru The PhoneSoulja Boy Tell 'em Featuring Sammie | 44 | Chart history → |
| 33 | Green LightJohn Legend Featuring Andre 3000 | 31 | Chart history → |
| 34 | DisturbiaRihanna | 33 | Chart history → |
| 35 | Thinking Of YouKaty Perry | 50 | Chart history → |
| 36 | One More DrinkLudacris Co-Starring T-Pain | 27 | Chart history → |
| 37 | Blame ItJamie Foxx Featuring T-Pain | 62 | Chart history → |
| 38 | Chicken FriedZac Brown Band | 36 | Chart history → |
| 39 | Light OnDavid Cook | 29 | Chart history → |
| 40 | White HorseTaylor Swift | 39 | Chart history → |
| 41 | Feel That FireDierks Bentley | 41 | Chart history → |
| 42 | God Love HerToby Keith | 42 | Chart history → |
| 43 | RehabRihanna | 30 | Chart history → |
| 44 | She Wouldn't Be GoneBlake Shelton | 43 | Chart history → |
| 45 | If I Were A BoyBeyonce | 34 | Chart history → |
| 46 | Rockin' That ThangThe-Dream | 57 | Chart history → |
| 47 | Better In TimeLeona Lewis | 45 | Chart history → |
| 48 | AddictedSaving Abel | 40 | Chart history → |
| 49 | Sweet ThingKeith Urban | 54 | Chart history → |
| 50 | Cowgirls Don't CryBrooks & Dunn Featuring Reba McEntire | 49 | Chart history → |
| 51 | Down The RoadKenny Chesney With Mac McAnally | 56 | Chart history → |
| 52 | Chopped 'N' SkrewedT-Pain Featuring Ludacris | 46 | Chart history → |
| 53 | HumanThe Killers | 48 | Chart history → |
| 54 | My PresidentYoung Jeezy Featuring Nas | 53 | Chart history → |
| 55 | I'm So PaidAkon Featuring Lil Wayne & Young Jeezy | 47 | Chart history → |
| 56 | Don'tBilly Currington | 52 | Chart history → |
| 57 | She Got Her OwnNe-Yo Featuring Jamie Foxx & Fabolous | 60 | Chart history → |
| 58 | Second ChanceShinedown | 59 | Chart history → |
| 59 | Country BoyAlan Jackson | 51 | Chart history → |
| 60 | HaloBeyonce | 93 | Chart history → |
| 61 | Just Like MeJamie Foxx Featuring T.I. | 64 | Chart history → |
| 62 | 1, 2, 3, 4Plain White T's | 91 | Chart history → |
| 63 | Day 'N' NiteKid Cudi | 73 | Chart history → |
| 64 | That's Not My NameThe Ting Tings | — | Chart history → |
| 65 | It Won't Be Like This For LongDarius Rucker | 71 | Chart history → |
| 66 | LuckyJason Mraz & Colbie Caillat | 82 | Chart history → |
| 67 | Sex On FireKings Of Leon | 65 | Listen & explore → |
| 68 | DecodeParamore | 61 | Chart history → |
| 69 | Trading PlacesUsher | 68 | Chart history → |
| 70 | La La LandDemi Lovato | 55 | Chart history → |
| 71 | River Of LoveGeorge Strait | 77 | Chart history → |
| 72 | Move (If You 'W'anna)Mims | 96 | Chart history → |
| 73 | Put It On YaPlies Featuring Chris J | 63 | Chart history → |
| 74 | Right RoundFlo Rida | — | Listen & explore → |
| 75 | Angels On The MoonThriving Ivory | 81 | Chart history → |
| 76 | KrazyPitbull Featuring Lil Jon | 83 | Chart history → |
| 77 | She's CountryJason Aldean | 88 | Chart history → |
| 78 | Crack A BottleEminem, Dr. Dre & 50 Cent | 78 | Chart history → |
| 79 | Don't Trust Me3OH!3 | 70 | Chart history → |
| 80 | BeepBobby V Featuring Yung Joc | 89 | Chart history → |
| 81 | Let MePat Green | 99 | Chart history → |
| 82 | FreezeT-Pain Featuring Chris Brown | — | Chart history → |
| 83 | You're Gonna Go Far, KidThe Offspring | 74 | Chart history → |
| 84 | IfULeaveMusiq Soulchild Featuring Mary J. Blige | 79 | Chart history → |
| 85 | Playa Cardz RightKeyshia Cole Featuring 2Pac | 85 | Chart history → |
| 86 | LostGorilla Zoe | 87 | Chart history → |
| 87 | Tell Me Something I Don't KnowSelena Gomez | 58 | Chart history → |
| 88 | Already GoneSugarland | 72 | Chart history → |
| 89 | Start A BandBrad Paisley Duet With Keith Urban | 69 | Chart history → |
| 90 | LollipopFraming Hanley | 86 | Chart history → |
| 91 | Last CallLee Ann Womack | 94 | Chart history → |
| 92 | More Like HerMiranda Lambert | 97 | Chart history → |
| 93 | BrokenLifehouse | 92 | Chart history → |
| 94 | I Will BeLeona Lewis | — | Chart history → |
| 95 | I Don't CareApocalyptica Featuring Adam Gontier | 90 | Chart history → |
| 96 | Get On Your BootsU2 | 37 | Chart history → |
| 97 | In ColorJamey Johnson | 80 | Chart history → |
| 98 | Don't Think I Can't Love YouJake Owen | — | Chart history → |
| 99 | Keeps Gettin' BetterChristina Aguilera | 76 | Chart history → |
| 100 | Ain't IYung L.A. Featuring Young Dro & T.I. | — | Chart history → |