| 1 | DownJay Sean Featuring Lil Wayne | 2 | Chart history → |
| 2 | Whatcha SayJason Derulo | 4 | Chart history → |
| 3 | Party In The U.S.A.Miley Cyrus | 3 | Listen & explore → |
| 4 | Run This TownJay-Z, Rihanna & Kanye West | 5 | Chart history → |
| 5 | 3Britney Spears | 1 | Chart history → |
| 6 | PaparazziLady Gaga | 7 | Chart history → |
| 7 | FirefliesOwl City | 9 | Chart history → |
| 8 | I Gotta FeelingThe Black Eyed Peas | 6 | Chart history → |
| 9 | Meet Me HalfwayThe Black Eyed Peas | 17 | Chart history → |
| 10 | You Belong With MeTaylor Swift | 8 | Chart history → |
| 11 | Sweet DreamsBeyonce | 12 | Chart history → |
| 12 | Empire State Of MindJay-Z + Alicia Keys | 13 | Chart history → |
| 13 | Use SomebodyKings Of Leon | 10 | Chart history → |
| 14 | ReplayIyaz | 14 | Chart history → |
| 15 | ForeverDrake Featuring Kanye West, Lil Wayne & Eminem | 15 | Chart history → |
| 16 | ObsessedMariah Carey | 11 | Chart history → |
| 17 | Who SaysJohn Mayer | — | Chart history → |
| 18 | Break UpMario Featuring Gucci Mane & Sean Garrett | 23 | Chart history → |
| 19 | Cowboy CasanovaCarrie Underwood | 20 | Chart history → |
| 20 | Already GoneKelly Clarkson | 19 | Chart history → |
| 21 | Sexy ChickDavid Guetta Featuring Akon | 25 | Chart history → |
| 22 | Need You NowLady Antebellum | 24 | Chart history → |
| 23 | One TimeJustin Bieber | 21 | Chart history → |
| 24 | Say Hey (I Love You)Michael Franti & Spearhead Featuring Cherine Anderson | 18 | Chart history → |
| 25 | Fallin' For YouColbie Caillat | 28 | Chart history → |
| 26 | ToesZac Brown Band | 29 | Chart history → |
| 27 | I Can Transform YaChris Brown Featuring Lil Wayne & Swizz Beatz | 52 | Chart history → |
| 28 | Love DrunkBoys Like Girls | 27 | Chart history → |
| 29 | Hotel Room ServicePitbull | 22 | Chart history → |
| 30 | Throw It In The BagFabolous Featuring The-Dream | 26 | Chart history → |
| 31 | Evacuate The DancefloorCascada | 39 | Chart history → |
| 32 | She WolfShakira | 31 | Chart history → |
| 33 | Gettin' You HomeChris Young | 38 | Chart history → |
| 34 | Only You Can Love Me This WayKeith Urban | 42 | Chart history → |
| 35 | Good Girls Go BadCobra Starship Featuring Leighton Meester | 32 | Chart history → |
| 36 | SuccessfulDrake Featuring Trey Songz & Lil Wayne | 34 | Listen & explore → |
| 37 | Be On YouFlo Rida Featuring Ne-Yo | 33 | Chart history → |
| 38 | Drop It LowEster Dean Featuring Chris Brown | 49 | Chart history → |
| 39 | Knock You DownKeri Hilson Featuring Kanye West & Ne-Yo | 36 | Chart history → |
| 40 | Good MorningChamillionaire | — | Chart history → |
| 41 | Best I Ever HadDrake | 37 | Listen & explore → |
| 42 | American RideToby Keith | 35 | Chart history → |
| 43 | WastedGucci Mane Featuring Plies Or OJ Da Juiceman | 47 | Chart history → |
| 44 | Big Green TractorJason Aldean | 43 | Chart history → |
| 45 | I Know You Want Me (Calle Ocho)Pitbull | 48 | Chart history → |
| 46 | Boom Boom PowThe Black Eyed Peas | 45 | Chart history → |
| 47 | Never Say NeverThe Fray | 41 | Chart history → |
| 48 | 21 GunsGreen Day | 51 | Chart history → |
| 49 | No SurpriseDaughtry | 46 | Chart history → |
| 50 | Do ILuke Bryan | 53 | Chart history → |
| 51 | Welcome To The FutureBrad Paisley | 56 | Chart history → |
| 52 | One Less Lonely GirlJustin Bieber | 16 | Chart history → |
| 53 | Imma Star (Everywhere We Are)Jeremih | 55 | Chart history → |
| 54 | I'm AliveKenny Chesney With Dave Matthews | 57 | Chart history → |
| 55 | TiK ToKKe$ha | 79 | Chart history → |
| 56 | Keep Holding OnGlee Cast | — | Chart history → |
| 57 | Haven't Met You YetMichael Buble | 90 | Chart history → |
| 58 | SmileUncle Kracker | 62 | Chart history → |
| 59 | Hey, Soul SisterTrain | 80 | Chart history → |
| 60 | FunhouseP!nk | 66 | Chart history → |
| 61 | Doesn't Mean AnythingAlicia Keys | 65 | Chart history → |
| 62 | Body LanguageJesse McCartney Featuring T-Pain | 71 | Chart history → |
| 63 | Face DropSean Kingston | 61 | Chart history → |
| 64 | UprisingMuse | 70 | Chart history → |
| 65 | No AirGlee Cast | — | Chart history → |
| 66 | Starstrukk3OH!3 Featuring Katy Perry | 72 | Chart history → |
| 67 | FifteenTaylor Swift | 77 | Chart history → |
| 68 | Small Town USAJustin Moore | 63 | Chart history → |
| 69 | LOL :-)Trey Songz Featuring Gucci Mane & Soulja Boy Tell'em | 59 | Chart history → |
| 70 | God In MeMary Mary Featuring Kierra "KiKi" Sheard | 69 | Chart history → |
| 71 | It's My Life / Confessions Part IIGlee Cast | 30 | Chart history → |
| 72 | La La LaLMFAO | 64 | Chart history → |
| 73 | RunawayLove And Theft | 75 | Chart history → |
| 74 | I'm Going InDrake Featuring Lil Wayne & Young Jeezy | 74 | Chart history → |
| 75 | Number OneR. Kelly Featuring Keri Hilson | 68 | Chart history → |
| 76 | NobodyWonder Girls | — | Chart history → |
| 77 | Mama's SongCarrie Underwood | — | Chart history → |
| 78 | I Will Not BowBreaking Benjamin | 73 | Chart history → |
| 79 | Red LightDavid Nail | 82 | Chart history → |
| 80 | Consider Me GoneReba | 86 | Chart history → |
| 81 | I Wanna Make You Close Your EyesDierks Bentley | 83 | Chart history → |
| 82 | UnderPleasure P | 78 | Chart history → |
| 83 | ChancesFive For Fighting | — | Chart history → |
| 84 | Halo / Walking On SunshineGlee Cast | 40 | Chart history → |
| 85 | All The Right MovesOneRepublic | 58 | Chart history → |
| 86 | BonfireCraig Morgan | 87 | Chart history → |
| 87 | Bad HabitsMaxwell | 88 | Chart history → |
| 88 | Kings And QueensThirty Seconds To Mars | — | Chart history → |
| 89 | You're A JerkNew Boyz | 84 | Chart history → |
| 90 | WheelsFoo Fighters | 81 | Chart history → |
| 91 | I Want To Know What Love IsMariah Carey | 67 | Chart history → |
| 92 | PapersUsher | — | Chart history → |
| 93 | Hell Of A LifeT.I. | 54 | Chart history → |
| 94 | Money To BlowBirdman Featuring Lil Wayne & Drake | 100 | Chart history → |
| 95 | BreakThree Days Grace | 89 | Chart history → |
| 96 | RegretLeToya Featuring Ludacris | — | Chart history → |
| 97 | Tie Me DownNew Boyz Featuring Ray J | — | Chart history → |
| 98 | White LiarMiranda Lambert | — | Chart history → |
| 99 | NotionKings Of Leon | — | Chart history → |
| 100 | Honky Tonk StompBrooks & Dunn Featuring Billy Gibbons | 97 | Chart history → |