| 1 | Empire State Of MindJay-Z + Alicia Keys | 1 | Chart history → |
| 2 | TiK ToKKe$ha | 3 | Chart history → |
| 3 | Bad RomanceLady Gaga | 2 | Chart history → |
| 4 | ReplayIyaz | 4 | Chart history → |
| 5 | FirefliesOwl City | 5 | Chart history → |
| 6 | Sexy ChickDavid Guetta Featuring Akon | 7 | Chart history → |
| 7 | Whatcha SayJason Derulo | 6 | Chart history → |
| 8 | Meet Me HalfwayThe Black Eyed Peas | 8 | Chart history → |
| 9 | 3Britney Spears | 9 | Chart history → |
| 10 | DownJay Sean Featuring Lil Wayne | 10 | Chart history → |
| 11 | PaparazziLady Gaga | 11 | Chart history → |
| 12 | Sweet DreamsBeyonce | 12 | Chart history → |
| 13 | How LowLudacris | — | Chart history → |
| 14 | ForeverDrake Featuring Kanye West, Lil Wayne & Eminem | 15 | Chart history → |
| 15 | Already GoneKelly Clarkson | 13 | Chart history → |
| 16 | Do You RememberJay Sean Featuring Sean Paul & Lil Jon | 19 | Chart history → |
| 17 | Party In The U.S.A.Miley Cyrus | 14 | Listen & explore → |
| 18 | I Gotta FeelingThe Black Eyed Peas | 17 | Chart history → |
| 19 | Need You NowLady Antebellum | 16 | Chart history → |
| 20 | BedRockYoung Money Featuring Lloyd | 24 | Chart history → |
| 21 | HardRihanna Featuring Jeezy | 20 | Chart history → |
| 22 | You Belong With MeTaylor Swift | 18 | Chart history → |
| 23 | Use SomebodyKings Of Leon | 21 | Chart history → |
| 24 | I Can Transform YaChris Brown Featuring Lil Wayne & Swizz Beatz | 22 | Chart history → |
| 25 | Evacuate The DancefloorCascada | 25 | Chart history → |
| 26 | Money To BlowBirdman Featuring Lil Wayne & Drake | 26 | Chart history → |
| 27 | FifteenTaylor Swift | 23 | Chart history → |
| 28 | Two Is Better Than OneBoys Like Girls Featuring Taylor Swift | 32 | Chart history → |
| 29 | Baby By Me50 Cent Featuring Ne-Yo | 31 | Chart history → |
| 30 | Cowboy CasanovaCarrie Underwood | 28 | Chart history → |
| 31 | Carry OutTimbaland Featuring Justin Timberlake | 75 | Chart history → |
| 32 | Run This TownJay-Z, Rihanna & Kanye West | 27 | Chart history → |
| 33 | Tie Me DownNew Boyz Featuring Ray J | 37 | Chart history → |
| 34 | Give It Up To MeShakira Featuring Lil Wayne | 29 | Chart history → |
| 35 | Gangsta LuvSnoop Dogg Featuring The-Dream | 39 | Chart history → |
| 36 | Live Like We're DyingKris Allen | 44 | Chart history → |
| 37 | Do ILuke Bryan | 35 | Chart history → |
| 38 | Say AahTrey Songz Featuring Fabolous | 40 | Chart history → |
| 39 | Fallin' For YouColbie Caillat | 33 | Chart history → |
| 40 | Consider Me GoneReba | 38 | Chart history → |
| 41 | One TimeJustin Bieber | 34 | Chart history → |
| 42 | SpotlightGucci Mane Featuring Usher | 48 | Chart history → |
| 43 | I Invented SexTrey Songz Featuring Drake | 43 | Chart history → |
| 44 | Russian RouletteRihanna | 30 | Chart history → |
| 45 | Hey, Soul SisterTrain | 45 | Chart history → |
| 46 | TelephoneLady Gaga Featuring Beyonce | 41 | Chart history → |
| 47 | If You Only KnewShinedown | 42 | Chart history → |
| 48 | The TruthJason Aldean | 47 | Chart history → |
| 49 | White LiarMiranda Lambert | 46 | Chart history → |
| 50 | Southern VoiceTim McGraw | 49 | Chart history → |
| 51 | My Life Would Suck Without YouGlee Cast | — | Chart history → |
| 52 | I Wanna Make You Close Your EyesDierks Bentley | 52 | Chart history → |
| 53 | Don't Rain On My ParadeGlee Cast | — | Chart history → |
| 54 | It Kills MeMelanie Fiona | 56 | Chart history → |
| 55 | According To YouOrianthi | 67 | Chart history → |
| 56 | Try Sleeping With A Broken HeartAlicia Keys | 51 | Chart history → |
| 57 | PapersUsher | 36 | Chart history → |
| 58 | SmileUncle Kracker | 53 | Chart history → |
| 59 | Red LightDavid Nail | 54 | Chart history → |
| 60 | CrawlChris Brown | 65 | Chart history → |
| 61 | Never Gonna Be AloneNickelback | 62 | Chart history → |
| 62 | On FireLil Wayne | — | Chart history → |
| 63 | In My HeadJason Derulo | — | Chart history → |
| 64 | Life After YouDaughtry | 66 | Chart history → |
| 65 | BonfireCraig Morgan | 57 | Chart history → |
| 66 | UprisingMuse | 59 | Chart history → |
| 67 | I AmMary J. Blige | — | Chart history → |
| 68 | WastedGucci Mane Featuring Plies Or OJ Da Juiceman | 58 | Chart history → |
| 69 | Body LanguageJesse McCartney Featuring T-Pain | 50 | Chart history → |
| 70 | History In The MakingDarius Rucker | 64 | Chart history → |
| 71 | You Can't Always Get What You WantGlee Cast | — | Chart history → |
| 72 | This Is WarThirty Seconds To Mars | — | Chart history → |
| 73 | One Less Lonely GirlJustin Bieber | 74 | Chart history → |
| 74 | Haven't Met You YetMichael Buble | 68 | Chart history → |
| 75 | Why Don't We Just DanceJosh Turner | 76 | Chart history → |
| 76 | SomedayRob Thomas | 72 | Chart history → |
| 77 | Eight Second RideJake Owen | 70 | Chart history → |
| 78 | Bad HabitsMaxwell | 71 | Chart history → |
| 79 | All The Right MovesOneRepublic | 77 | Chart history → |
| 80 | I Wanna RockSnoop Dogg | — | Chart history → |
| 81 | I Will Not BowBreaking Benjamin | 78 | Chart history → |
| 82 | Kings And QueensThirty Seconds To Mars | 94 | Chart history → |
| 83 | Shut It DownPitbull Featuring Akon | 85 | Chart history → |
| 84 | BreakThree Days Grace | 82 | Chart history → |
| 85 | That's How Country Boys RollBilly Currington | 87 | Chart history → |
| 86 | Gettin' You HomeChris Young | 80 | Chart history → |
| 87 | 1901Phoenix | 90 | Chart history → |
| 88 | What I DoChris Brown Featuring Plies | — | Chart history → |
| 89 | Last ChristmasGlee Cast | 63 | Chart history → |
| 90 | American Saturday NightBrad Paisley | 100 | Chart history → |
| 91 | Cryin' For Me (Wayman's Song)Toby Keith | 97 | Chart history → |
| 92 | I Get It InOmarion Featuring Gucci Mane | 83 | Chart history → |
| 93 | BreakevenThe Script | 96 | Chart history → |
| 94 | And I Am Telling You I'm Not GoingGlee Cast | — | Chart history → |
| 95 | (If You're Wondering If I Want You To) I Want You ToWeezer | 86 | Chart history → |
| 96 | I'm Going InDrake Featuring Lil Wayne & Young Jeezy | 84 | Chart history → |
| 97 | Video PhoneBeyonce Featuring Lady Gaga | 81 | Chart history → |
| 98 | Drop It LowEster Dean Featuring Chris Brown | 92 | Chart history → |
| 99 | Halfway GoneLifehouse | — | Chart history → |
| 100 | TwangGeorge Strait | — | Chart history → |