| 1 | Let Me Love YouMario | 1 | Chart history → |
| 2 | 1, 2 StepCiara Featuring Missy Elliott | 2 | Chart history → |
| 3 | Drop It Like It's HotSnoop Dogg Featuring Pharrell | 3 | Chart history → |
| 4 | Lovers And FriendsLil Jon & The East Side Boyz Featuring Usher & Ludacris | 4 | Chart history → |
| 5 | SoldierDestiny's Child Featuring T.I. & Lil Wayne | 5 | Chart history → |
| 6 | My BooUsher And Alicia Keys | 6 | Chart history → |
| 7 | Over And OverNelly Featuring Tim McGraw | 7 | Chart history → |
| 8 | Disco Inferno50 Cent | 9 | Chart history → |
| 9 | WonderfulJa Rule Featuring R. Kelly & Ashanti | 8 | Chart history → |
| 10 | BreakawayKelly Clarkson | 11 | Chart history → |
| 11 | How We DoThe Game Featuring 50 Cent | 13 | Chart history → |
| 12 | I Don't Want To BeGavin DeGraw | 12 | Chart history → |
| 13 | Lose My BreathDestiny's Child | 10 | Chart history → |
| 14 | Only UAshanti | 15 | Chart history → |
| 15 | Get BackLudacris | 14 | Chart history → |
| 16 | Boulevard Of Broken DreamsGreen Day | 16 | Chart history → |
| 17 | She Will Be LovedMaroon 5 | 18 | Chart history → |
| 18 | Bring Em OutT.I. | 20 | Chart history → |
| 19 | GoodiesCiara Featuring Petey Pablo | 21 | Chart history → |
| 20 | Let's GoTrick Daddy Featuring Lil Jon & Twista | 17 | Chart history → |
| 21 | KarmaLloyd Banks Featuring Avant | 19 | Chart history → |
| 22 | DaughtersJohn Mayer | 30 | Chart history → |
| 23 | Numb/EncoreJay-Z/Linkin Park | 23 | Chart history → |
| 24 | What U Gon' DoLil Jon & The East Side Boyz Featuring Lil Scrappy | 22 | Chart history → |
| 25 | Dare You To MoveSwitchfoot | 25 | Chart history → |
| 26 | Oye Mi CantoN.O.R.E. Featuring Daddy Yankee, Nina Sky, Gem Star & Big Mato | 26 | Chart history → |
| 27 | CharleneAnthony Hamilton | 27 | Chart history → |
| 28 | TrueRyan Cabrera | 29 | Chart history → |
| 29 | One ThingFinger Eleven | 35 | Chart history → |
| 30 | New YorkJa Rule Featuring Fat Joe & Jadakiss | 31 | Chart history → |
| 31 | Lean BackTerror Squad | 39 | Chart history → |
| 32 | Since U Been GoneKelly Clarkson | 32 | Chart history → |
| 33 | U Make Me WannaJadakiss Featuring Mariah Carey | 24 | Chart history → |
| 34 | Beautiful SoulJesse McCartney | 34 | Chart history → |
| 35 | BrokenSeether Featuring Amy Lee | 33 | Chart history → |
| 36 | KarmaAlicia Keys | 36 | Chart history → |
| 37 | On The Way DownRyan Cabrera | 41 | Chart history → |
| 38 | Some BeachBlake Shelton | 38 | Chart history → |
| 39 | EncoreEminem, Dr. Dre & 50 Cent | 28 | Chart history → |
| 40 | VertigoU2 | 37 | Chart history → |
| 41 | Awful, Beautiful LifeDarryl Worley | 49 | Chart history → |
| 42 | Back WhenTim McGraw | 45 | Chart history → |
| 43 | GasolinaDaddy Yankee | 44 | Chart history → |
| 44 | My Happy EndingAvril Lavigne | 47 | Chart history → |
| 45 | BreatheFabolous | 40 | Chart history → |
| 46 | When I Think About Cheatin'Gretchen Wilson | 52 | Chart history → |
| 47 | Go D.J.Lil Wayne | 43 | Chart history → |
| 48 | Shorty Wanna RideYoung Buck | 46 | Chart history → |
| 49 | Bless The Broken RoadRascal Flatts | 55 | Chart history → |
| 50 | You're My Better HalfKeith Urban | 57 | Chart history → |
| 51 | LadyLenny Kravitz | 51 | Chart history → |
| 52 | Baby It's YouJoJo Featuring Bow Wow | 42 | Chart history → |
| 53 | Mud On The TiresBrad Paisley | 59 | Chart history → |
| 54 | Nobody's HomeAvril Lavigne | 48 | Chart history → |
| 55 | Give A Little BitGoo Goo Dolls | 58 | Chart history → |
| 56 | Welcome To My LifeSimple Plan | 50 | Chart history → |
| 57 | Rich GirlGwen Stefani Featuring Eve | 54 | Chart history → |
| 58 | Caught UpUsher | 60 | Chart history → |
| 59 | Nothin 'Bout Love Makes SenseLeAnn Rimes | 69 | Chart history → |
| 60 | How Am I Doin'Dierks Bentley | 61 | Chart history → |
| 61 | Monday Morning ChurchAlan Jackson | 71 | Chart history → |
| 62 | Balla BabyChingy | 56 | Chart history → |
| 63 | Some CutTrillville Featuring Cutty | 63 | Chart history → |
| 64 | Nothing On But The RadioGary Allan | 65 | Chart history → |
| 65 | Just Lose ItEminem | 53 | Chart history → |
| 66 | The Woman With YouKenny Chesney | 67 | Chart history → |
| 67 | 1985Bowling For Soup | 66 | Chart history → |
| 68 | Tempted To TouchRupee | 68 | Chart history → |
| 69 | Somebody Told MeThe Killers | 62 | Chart history → |
| 70 | Party For TwoShania Twain With Billy Currington Or Mark McGrath | 74 | Chart history → |
| 71 | Mr. MomLonestar | 70 | Chart history → |
| 72 | He Gets That From MeReba McEntire | 78 | Chart history → |
| 73 | MockingbirdEminem | 64 | Chart history → |
| 74 | Sunday MorningMaroon 5 | 75 | Chart history → |
| 75 | Let's Get BlownSnoop Dogg | 76 | Chart history → |
| 76 | Ordinary PeopleJohn Legend | 73 | Chart history → |
| 77 | I Changed My MindKeyshia Cole Featuring Shyne | 72 | Chart history → |
| 78 | HushLL Cool J Featuring 7 Aurelius | 82 | Chart history → |
| 79 | Vitamin R (Leading Us Along)Chevelle | 79 | Chart history → |
| 80 | So ColdBreaking Benjamin | 77 | Chart history → |
| 81 | Holy WaterBig & Rich | 85 | Chart history → |
| 82 | Fall To PiecesVelvet Revolver | 80 | Chart history → |
| 83 | Baby GirlSugarland | 88 | Chart history → |
| 84 | In A Real LovePhil Vassar | 89 | Chart history → |
| 85 | Getting Away With MurderPapa Roach | 84 | Chart history → |
| 86 | You're The OneGuerilla Black Featuring Mario Winans | 83 | Chart history → |
| 87 | Come Home SoonSHeDAISY | 86 | Chart history → |
| 88 | OkayNivea Featuring Lil Jon & YoungBloodZ | 91 | Chart history → |
| 89 | Dangerously In LoveBeyonce | 92 | Chart history → |
| 90 | Gotta Go SoloPatti LaBelle Featuring Ron Isley | 97 | Chart history → |
| 91 | What You Waiting For?Gwen Stefani | 90 | Chart history → |
| 92 | Take Me HomeTerror Squad | 94 | Chart history → |
| 93 | GhettoAkon | 95 | Chart history → |
| 94 | I Smoke, I DrankBody Head Bangerz Featuring YoungBloodz | 96 | Chart history → |
| 95 | Hold You DownThe Alchemist Featuring Prodigy, Illa Ghee & Nina Sky | 99 | Chart history → |
| 96 | PerdidosMonchy & Alexandra | 93 | Chart history → |
| 97 | A Rose By Any Other NameTeena Marie Featuring Gerald Levert | — | Chart history → |
| 98 | Thugs Get Lonely Too2Pac Featuring Nate Dogg | 100 | Chart history → |
| 99 | I'll Be AroundDaryl Hall John Oates | — | Chart history → |
| 100 | Real BigMannie Fresh | — | Chart history → |