| 1 | Let Me Love YouMario | 1 | Chart history → |
| 2 | 1, 2 StepCiara Featuring Missy Elliott | 2 | Chart history → |
| 3 | Lovers And FriendsLil Jon & The East Side Boyz Featuring Usher & Ludacris | 3 | Chart history → |
| 4 | SoldierDestiny's Child Featuring T.I. & Lil Wayne | 5 | Chart history → |
| 5 | Drop It Like It's HotSnoop Dogg Featuring Pharrell | 4 | Chart history → |
| 6 | How We DoThe Game Featuring 50 Cent | 9 | Chart history → |
| 7 | Disco Inferno50 Cent | 8 | Chart history → |
| 8 | Boulevard Of Broken DreamsGreen Day | 11 | Chart history → |
| 9 | My BooUsher And Alicia Keys | 6 | Chart history → |
| 10 | Over And OverNelly Featuring Tim McGraw | 7 | Chart history → |
| 11 | I Don't Want To BeGavin DeGraw | 10 | Chart history → |
| 12 | BreakawayKelly Clarkson | 12 | Chart history → |
| 13 | Get BackLudacris | 15 | Chart history → |
| 14 | Bring Em OutT.I. | 18 | Chart history → |
| 15 | Only UAshanti | 13 | Chart history → |
| 16 | WonderfulJa Rule Featuring R. Kelly & Ashanti | 14 | Chart history → |
| 17 | KarmaLloyd Banks Featuring Avant | 21 | Chart history → |
| 18 | TrueRyan Cabrera | 20 | Chart history → |
| 19 | DaughtersJohn Mayer | 19 | Chart history → |
| 20 | Since U Been GoneKelly Clarkson | 22 | Chart history → |
| 21 | Lose My BreathDestiny's Child | 16 | Chart history → |
| 22 | She Will Be LovedMaroon 5 | 17 | Chart history → |
| 23 | Beautiful SoulJesse McCartney | 24 | Chart history → |
| 24 | Caught UpUsher | 42 | Chart history → |
| 25 | Numb/EncoreJay-Z/Linkin Park | 23 | Chart history → |
| 26 | MockingbirdEminem | 51 | Chart history → |
| 27 | Dare You To MoveSwitchfoot | 28 | Chart history → |
| 28 | Rich GirlGwen Stefani Featuring Eve | 50 | Chart history → |
| 29 | KarmaAlicia Keys | 29 | Chart history → |
| 30 | GoodiesCiara Featuring Petey Pablo | 26 | Chart history → |
| 31 | What U Gon' DoLil Jon & The East Side Boyz Featuring Lil Scrappy | 27 | Chart history → |
| 32 | GasolinaDaddy Yankee | 35 | Chart history → |
| 33 | Awful, Beautiful LifeDarryl Worley | 30 | Chart history → |
| 34 | Mud On The TiresBrad Paisley | 43 | Chart history → |
| 35 | Let's GoTrick Daddy Featuring Lil Jon & Twista | 25 | Chart history → |
| 36 | You're My Better HalfKeith Urban | 40 | Chart history → |
| 37 | Bless The Broken RoadRascal Flatts | 41 | Chart history → |
| 38 | U Make Me WannaJadakiss Featuring Mariah Carey | 33 | Chart history → |
| 39 | When I Think About Cheatin'Gretchen Wilson | 44 | Chart history → |
| 40 | New YorkJa Rule Featuring Fat Joe & Jadakiss | 31 | Chart history → |
| 41 | Get RightJennifer Lopez | 53 | Chart history → |
| 42 | CharleneAnthony Hamilton | 32 | Chart history → |
| 43 | LadyLenny Kravitz | 47 | Chart history → |
| 44 | Some BeachBlake Shelton | 34 | Chart history → |
| 45 | Nobody's HomeAvril Lavigne | 52 | Chart history → |
| 46 | One ThingFinger Eleven | 37 | Chart history → |
| 47 | Some CutTrillville Featuring Cutty | 57 | Chart history → |
| 48 | Ordinary PeopleJohn Legend | 65 | Chart history → |
| 49 | Give A Little BitGoo Goo Dolls | 54 | Chart history → |
| 50 | On The Way DownRyan Cabrera | 45 | Chart history → |
| 51 | Truth IsFantasia | 73 | Chart history → |
| 52 | VertigoU2 | 38 | Chart history → |
| 53 | It's Like ThatMariah Carey | — | Chart history → |
| 54 | Nothin 'Bout Love Makes SenseLeAnn Rimes | 56 | Chart history → |
| 55 | Back WhenTim McGraw | 39 | Chart history → |
| 56 | EncoreEminem, Dr. Dre & 50 Cent | 46 | Chart history → |
| 57 | Monday Morning ChurchAlan Jackson | 58 | Chart history → |
| 58 | Sunday MorningMaroon 5 | 55 | Chart history → |
| 59 | OOmarion | 68 | Chart history → |
| 60 | Nothin' To LoseJosh Gracin | 70 | Chart history → |
| 61 | He Gets That From MeReba McEntire | 64 | Chart history → |
| 62 | Let's Get BlownSnoop Dogg | 66 | Chart history → |
| 63 | Obsession (No Es Amor)Frankie J Featuring Baby Bash | — | Chart history → |
| 64 | Like Toy SoldiersEminem | — | Chart history → |
| 65 | U Don't Know MeT.I. | 77 | Chart history → |
| 66 | Go D.J.Lil Wayne | 59 | Chart history → |
| 67 | Nothing On But The RadioGary Allan | 63 | Chart history → |
| 68 | Baby It's YouJoJo Featuring Bow Wow | 60 | Chart history → |
| 69 | Baby GirlSugarland | 81 | Chart history → |
| 70 | Look What You've DoneJet | — | Chart history → |
| 71 | Mr. MomLonestar | 67 | Chart history → |
| 72 | Shorty Wanna RideYoung Buck | 62 | Chart history → |
| 73 | I May Hate Myself In The MorningLee Ann Womack | — | Chart history → |
| 74 | Let Them Be LittleBilly Dean | — | Chart history → |
| 75 | Tempted To TouchRupee | 74 | Chart history → |
| 76 | Holy WaterBig & Rich | 78 | Chart history → |
| 77 | BabyFabolous Featuring Mike Shorey | 83 | Chart history → |
| 78 | Welcome To My LifeSimple Plan | 71 | Chart history → |
| 79 | How Am I Doin'Dierks Bentley | 69 | Chart history → |
| 80 | OkayNivea Featuring Lil Jon & YoungBloodZ | 84 | Chart history → |
| 81 | Party For TwoShania Twain With Billy Currington Or Mark McGrath | 72 | Chart history → |
| 82 | The Woman With YouKenny Chesney | 76 | Chart history → |
| 83 | BreatheFabolous | 61 | Chart history → |
| 84 | Fall To PiecesVelvet Revolver | 85 | Chart history → |
| 85 | Sugar (Gimme Some)Trick Daddy Featuring Ludacris, Lil' Kim & Cee-Lo | 100 | Chart history → |
| 86 | Getting Away With MurderPapa Roach | 86 | Chart history → |
| 87 | Balla BabyChingy | 79 | Chart history → |
| 88 | Vitamin R (Leading Us Along)Chevelle | 88 | Chart history → |
| 89 | You're The OneGuerilla Black Featuring Mario Winans | 89 | Chart history → |
| 90 | Just Lose ItEminem | 80 | Chart history → |
| 91 | I Smoke, I DrankBody Head Bangerz Featuring YoungBloodz | 93 | Chart history → |
| 92 | Gotta Go SoloPatti LaBelle Featuring Ron Isley | 95 | Chart history → |
| 93 | I Changed My MindKeyshia Cole Featuring Shyne | 87 | Chart history → |
| 94 | PerdidosMonchy & Alexandra | 97 | Chart history → |
| 95 | Take Me HomeTerror Squad | 98 | Chart history → |
| 96 | Hold You DownThe Alchemist Featuring Prodigy, Illa Ghee & Nina Sky | 99 | Chart history → |
| 97 | What You Waiting For?Gwen Stefani | 96 | Chart history → |
| 98 | GhettoAkon | 92 | Chart history → |
| 99 | I'll Be AroundDaryl Hall John Oates | — | Chart history → |
| 100 | Dangerously In LoveBeyonce | 90 | Chart history → |