| 1 | You're BeautifulJames Blunt | 2 | Chart history → |
| 2 | Check On ItBeyonce Featuring Slim Thug | 1 | Chart history → |
| 3 | TemperatureSean Paul | 4 | Chart history → |
| 4 | GrillzNelly Featuring Paul Wall, Ali & Gipp | 3 | Chart history → |
| 5 | Be Without YouMary J. Blige | 5 | Chart history → |
| 6 | I'm N Luv (Wit A Stripper)T-Pain Featuring Mike Jones | 6 | Chart history → |
| 7 | Yo (Excuse Me Miss)Chris Brown | 7 | Chart history → |
| 8 | UnwrittenNatasha Bedingfield | 9 | Chart history → |
| 9 | So SickNe-Yo | 8 | Chart history → |
| 10 | Everytime We TouchCascada | 16 | Chart history → |
| 11 | Lean Wit It, Rock Wit ItDem Franchize Boyz Featuring Lil Peanut & Charlay | 11 | Chart history → |
| 12 | Shake ThatEminem Featuring Nate Dogg | 10 | Chart history → |
| 13 | UnpredictableJamie Foxx Featuring Ludacris | 12 | Chart history → |
| 14 | Dirty Little SecretThe All-American Rejects | 14 | Chart history → |
| 15 | Dance, DanceFall Out Boy | 15 | Chart history → |
| 16 | Touch ItBusta Rhymes | 24 | Chart history → |
| 17 | Stupid GirlsP!nk | 13 | Chart history → |
| 18 | Pump ItThe Black Eyed Peas | 20 | Chart history → |
| 19 | Run It!Chris Brown | 17 | Chart history → |
| 20 | Because Of YouKelly Clarkson | 19 | Chart history → |
| 21 | Ms. New BootyBubba Sparxxx Featuring Ying Yang Twins & Mr. ColliPark | 31 | Chart history → |
| 22 | StickwituThe Pussycat Dolls | 18 | Chart history → |
| 23 | Gold DiggerKanye West Featuring Jamie Foxx | 21 | Chart history → |
| 24 | My HumpsThe Black Eyed Peas | 23 | Chart history → |
| 25 | LoveKeyshia Cole | 28 | Chart history → |
| 26 | One WishRay J | 22 | Chart history → |
| 27 | Walk AwayKelly Clarkson | 32 | Chart history → |
| 28 | Jesus, Take The WheelCarrie Underwood | 29 | Chart history → |
| 29 | Bad DayDaniel Powter | 41 | Chart history → |
| 30 | PhotographNickelback | 25 | Chart history → |
| 31 | BeepThe Pussycat Dolls Featuring will.i.am | 50 | Chart history → |
| 32 | Fresh AzimizBow Wow Featuring J-Kwon & Jermaine Dupri | 38 | Chart history → |
| 33 | There It Go! (The Whistle Song)Juelz Santana | 26 | Chart history → |
| 34 | Laffy TaffyD4L | 27 | Chart history → |
| 35 | You And MeLifehouse | 33 | Chart history → |
| 36 | Sugar, We're Goin' DownFall Out Boy | 35 | Chart history → |
| 37 | Who Says You Can't Go HomeBon Jovi | 54 | Chart history → |
| 38 | Your ManJosh Turner | 44 | Chart history → |
| 39 | RompeDaddy Yankee | 36 | Chart history → |
| 40 | Feel Good IncGorillaz | 34 | Chart history → |
| 41 | We Be Burnin'Sean Paul | 39 | Chart history → |
| 42 | When I Get Where I'm GoingBrad Paisley Featuring Dolly Parton | 40 | Chart history → |
| 43 | Tonight I Wanna CryKeith Urban | 45 | Chart history → |
| 44 | RodeoJuvenile | 47 | Chart history → |
| 45 | L.O.V.E.Ashlee Simpson | 30 | Chart history → |
| 46 | Honky Tonk BadonkadonkTrace Adkins | 42 | Chart history → |
| 47 | Don't Forget About UsMariah Carey | 37 | Chart history → |
| 48 | Upside DownJack Johnson | 43 | Chart history → |
| 49 | CrashGwen Stefani | 49 | Chart history → |
| 50 | I Think They Like MeDem Franchize Boyz Featuring Jermaine Dupri, Da Brat & Bow Wow | 46 | Chart history → |
| 51 | Perfect SituationWeezer | 53 | Chart history → |
| 52 | Touch The SkyKanye West Featuring Lupe Fiasco | 70 | Chart history → |
| 53 | For You I Will (Confidence)Teddy Geiger | 55 | Chart history → |
| 54 | Hung UpMadonna | 48 | Listen & explore → |
| 55 | Living In Fast ForwardKenny Chesney | 63 | Chart history → |
| 56 | SOSRihanna | 69 | Chart history → |
| 57 | Ever The SameRob Thomas | 68 | Chart history → |
| 58 | Turn It UpChamillionaire Featuring Lil' Flip | 59 | Chart history → |
| 59 | RushAly & AJ | 92 | Chart history → |
| 60 | Black SweatPrince | — | Chart history → |
| 61 | King Without A CrownMatisyahu | 73 | Chart history → |
| 62 | Girl Next DoorSaving Jane | 83 | Chart history → |
| 63 | Nasty GirlThe Notorious B.I.G. Featuring Diddy, Nelly, Jagged Edge & Avery Storm | 57 | Chart history → |
| 64 | KeroseneMiranda Lambert | 62 | Chart history → |
| 65 | Oh Yes (aka 'Postman')Juelz Santana | 64 | Chart history → |
| 66 | Lights And SoundsYellowcard | 66 | Chart history → |
| 67 | She Don't Tell Me ToMontgomery Gentry | 71 | Chart history → |
| 68 | Get Drunk And Be SomebodyToby Keith | 74 | Chart history → |
| 69 | Looking For YouKirk Franklin | 77 | Chart history → |
| 70 | SorryMadonna | — | Chart history → |
| 71 | Move AlongThe All-American Rejects | 67 | Chart history → |
| 72 | Best Friend50 Cent & Olivia | — | Chart history → |
| 73 | Ridin'Chamillionaire Featuring Krayzie Bone | 88 | Chart history → |
| 74 | When I'm GoneEminem | 56 | Chart history → |
| 75 | BelieveBrooks & Dunn | 76 | Chart history → |
| 76 | Kryptonite (I'm On It)Purple Ribbon All-Stars | 61 | Chart history → |
| 77 | Betcha Can't Do It Like MeD4L | 72 | Chart history → |
| 78 | What Hurts The MostRascal Flatts | 79 | Chart history → |
| 79 | Just Might (Make Me Believe)Sugarland | 65 | Chart history → |
| 80 | Breaking FreeZac Efron, Andrew Seeley & Vanessa Anne Hudgens | 51 | Chart history → |
| 81 | Who I Am Hates Who I've BeenRelient K | 58 | Chart history → |
| 82 | Nobody But MeBlake Shelton | 81 | Chart history → |
| 83 | Over My Head (Cable Car)The Fray | 89 | Chart history → |
| 84 | Cheatin'Sara Evans | 84 | Chart history → |
| 85 | My HoodYoung Jeezy | 80 | Chart history → |
| 86 | Poppin' My CollarThree 6 Mafia | 91 | Chart history → |
| 87 | Gotta GoTrey Songz | 75 | Chart history → |
| 88 | Tell Me When To GoE-40 Featuring Keak Da Sneak | 99 | Chart history → |
| 89 | What's Left Of MeNick Lachey | — | Chart history → |
| 90 | In My MindHeather Headley | 98 | Chart history → |
| 91 | BoondocksLittle Big Town | 85 | Listen & explore → |
| 92 | Bring Out The Freak In YouLil Rob | 93 | Chart history → |
| 93 | Control MyselfLL Cool J Featuring Jennifer Lopez | — | Chart history → |
| 94 | LuxuriousGwen Stefani | 90 | Chart history → |
| 95 | TalkColdplay | 86 | Chart history → |
| 96 | FiremanLil Wayne | 78 | Chart history → |
| 97 | Wings Of A ButterflyHIM | — | Chart history → |
| 98 | DareGorillaz Featuring Shaun Ryder | 100 | Chart history → |
| 99 | She Let Herself GoGeorge Strait | 96 | Chart history → |
| 100 | AnimalsNickelback | — | Chart history → |