| 1 | So SickNe-Yo | 9 | Chart history → |
| 2 | TemperatureSean Paul | 3 | Chart history → |
| 3 | You're BeautifulJames Blunt | 1 | Chart history → |
| 4 | Be Without YouMary J. Blige | 5 | Chart history → |
| 5 | Check On ItBeyonce Featuring Slim Thug | 2 | Chart history → |
| 6 | I'm N Luv (Wit A Stripper)T-Pain Featuring Mike Jones | 6 | Chart history → |
| 7 | GrillzNelly Featuring Paul Wall, Ali & Gipp | 4 | Chart history → |
| 8 | Yo (Excuse Me Miss)Chris Brown | 7 | Chart history → |
| 9 | Lean Wit It, Rock Wit ItDem Franchize Boyz Featuring Lil Peanut & Charlay | 11 | Chart history → |
| 10 | UnwrittenNatasha Bedingfield | 8 | Chart history → |
| 11 | Everytime We TouchCascada | 10 | Chart history → |
| 12 | Shake ThatEminem Featuring Nate Dogg | 12 | Chart history → |
| 13 | UnpredictableJamie Foxx Featuring Ludacris | 13 | Chart history → |
| 14 | Bad DayDaniel Powter | 29 | Chart history → |
| 15 | Ms. New BootyBubba Sparxxx Featuring Ying Yang Twins & Mr. ColliPark | 21 | Chart history → |
| 16 | Dance, DanceFall Out Boy | 15 | Chart history → |
| 17 | Touch ItBusta Rhymes | 16 | Chart history → |
| 18 | Dirty Little SecretThe All-American Rejects | 14 | Chart history → |
| 19 | Stupid GirlsP!nk | 17 | Chart history → |
| 20 | LoveKeyshia Cole | 25 | Chart history → |
| 21 | Pump ItThe Black Eyed Peas | 18 | Chart history → |
| 22 | Because Of YouKelly Clarkson | 20 | Chart history → |
| 23 | Run It!Chris Brown | 19 | Chart history → |
| 24 | Jesus, Take The WheelCarrie Underwood | 28 | Chart history → |
| 25 | BeepThe Pussycat Dolls Featuring will.i.am | 31 | Chart history → |
| 26 | Walk AwayKelly Clarkson | 27 | Chart history → |
| 27 | StickwituThe Pussycat Dolls | 22 | Chart history → |
| 28 | My HumpsThe Black Eyed Peas | 24 | Chart history → |
| 29 | Gold DiggerKanye West Featuring Jamie Foxx | 23 | Chart history → |
| 30 | One WishRay J | 26 | Chart history → |
| 31 | RompeDaddy Yankee | 39 | Chart history → |
| 32 | Fresh AzimizBow Wow Featuring J-Kwon & Jermaine Dupri | 32 | Chart history → |
| 33 | PhotographNickelback | 30 | Chart history → |
| 34 | Who Says You Can't Go HomeBon Jovi | 37 | Chart history → |
| 35 | Always On Your SideSheryl Crow & Sting | — | Chart history → |
| 36 | Tonight I Wanna CryKeith Urban | 43 | Chart history → |
| 37 | You And MeLifehouse | 35 | Chart history → |
| 38 | Your ManJosh Turner | 38 | Chart history → |
| 39 | Sugar, We're Goin' DownFall Out Boy | 36 | Chart history → |
| 40 | When I Get Where I'm GoingBrad Paisley Featuring Dolly Parton | 42 | Chart history → |
| 41 | RodeoJuvenile | 44 | Chart history → |
| 42 | Laffy TaffyD4L | 34 | Chart history → |
| 43 | There It Go! (The Whistle Song)Juelz Santana | 33 | Chart history → |
| 44 | Feel Good IncGorillaz | 40 | Chart history → |
| 45 | We Be Burnin'Sean Paul | 41 | Chart history → |
| 46 | SOSRihanna | 56 | Chart history → |
| 47 | Touch The SkyKanye West Featuring Lupe Fiasco | 52 | Chart history → |
| 48 | Living In Fast ForwardKenny Chesney | 55 | Chart history → |
| 49 | I Think They Like MeDem Franchize Boyz Featuring Jermaine Dupri, Da Brat & Bow Wow | 50 | Chart history → |
| 50 | L.O.V.E.Ashlee Simpson | 45 | Chart history → |
| 51 | Upside DownJack Johnson | 48 | Chart history → |
| 52 | Ever The SameRob Thomas | 57 | Chart history → |
| 53 | Honky Tonk BadonkadonkTrace Adkins | 46 | Chart history → |
| 54 | Girl Next DoorSaving Jane | 62 | Chart history → |
| 55 | For You I Will (Confidence)Teddy Geiger | 53 | Chart history → |
| 56 | Oh Yes (aka 'Postman')Juelz Santana | 65 | Chart history → |
| 57 | Ridin'Chamillionaire Featuring Krayzie Bone | 73 | Chart history → |
| 58 | SorryMadonna | 70 | Chart history → |
| 59 | Perfect SituationWeezer | 51 | Chart history → |
| 60 | Best Friend50 Cent & Olivia | 72 | Chart history → |
| 61 | King Without A CrownMatisyahu | 61 | Chart history → |
| 62 | RushAly & AJ | 59 | Chart history → |
| 63 | Turn It UpChamillionaire Featuring Lil' Flip | 58 | Chart history → |
| 64 | Over My Head (Cable Car)The Fray | 83 | Chart history → |
| 65 | She Don't Tell Me ToMontgomery Gentry | 67 | Chart history → |
| 66 | What Hurts The MostRascal Flatts | 78 | Chart history → |
| 67 | What's Left Of MeNick Lachey | 89 | Chart history → |
| 68 | Get Drunk And Be SomebodyToby Keith | 68 | Chart history → |
| 69 | BelieveBrooks & Dunn | 75 | Chart history → |
| 70 | CrashGwen Stefani | 49 | Chart history → |
| 71 | Looking For YouKirk Franklin | 69 | Chart history → |
| 72 | Poppin' My CollarThree 6 Mafia | 86 | Chart history → |
| 73 | Tell Me When To GoE-40 Featuring Keak Da Sneak | 88 | Chart history → |
| 74 | Hung UpMadonna | 54 | Listen & explore → |
| 75 | Move AlongThe All-American Rejects | 71 | Chart history → |
| 76 | Nobody But MeBlake Shelton | 82 | Chart history → |
| 77 | Lights And SoundsYellowcard | 66 | Chart history → |
| 78 | Nasty GirlThe Notorious B.I.G. Featuring Diddy, Nelly, Jagged Edge & Avery Storm | 63 | Chart history → |
| 79 | Betcha Can't Do It Like MeD4L | 77 | Chart history → |
| 80 | Cheatin'Sara Evans | 84 | Chart history → |
| 81 | KeroseneMiranda Lambert | 64 | Chart history → |
| 82 | Gotta GoTrey Songz | 87 | Chart history → |
| 83 | What You KnowT.I. | — | Chart history → |
| 84 | In My MindHeather Headley | 90 | Chart history → |
| 85 | Breaking FreeZac Efron, Andrew Seeley & Vanessa Anne Hudgens | 80 | Chart history → |
| 86 | Kryptonite (I'm On It)Purple Ribbon All-Stars | 76 | Chart history → |
| 87 | Wings Of A ButterflyHIM | 97 | Chart history → |
| 88 | Just Might (Make Me Believe)Sugarland | 79 | Chart history → |
| 89 | Control MyselfLL Cool J Featuring Jennifer Lopez | 93 | Chart history → |
| 90 | Bring Out The Freak In YouLil Rob | 92 | Chart history → |
| 91 | When I'm GoneEminem | 74 | Chart history → |
| 92 | My HoodYoung Jeezy | 85 | Chart history → |
| 93 | Can't Let GoAnthony Hamilton | — | Chart history → |
| 94 | Savin' MeNickelback | — | Chart history → |
| 95 | GirlPaul Wall | — | Chart history → |
| 96 | WhyJason Aldean | — | Chart history → |
| 97 | Who I Am Hates Who I've BeenRelient K | 81 | Chart history → |
| 98 | I Write Sins Not TragediesPanic! At The Disco | — | Chart history → |
| 99 | When You're MadNe-Yo | — | Chart history → |
| 100 | LuxuriousGwen Stefani | 94 | Chart history → |