| 1 | TemperatureSean Paul | 2 | Chart history → |
| 2 | Bad DayDaniel Powter | 5 | Chart history → |
| 3 | So SickNe-Yo | 1 | Chart history → |
| 4 | You're BeautifulJames Blunt | 3 | Chart history → |
| 5 | Be Without YouMary J. Blige | 4 | Chart history → |
| 6 | UnwrittenNatasha Bedingfield | 7 | Chart history → |
| 7 | Lean Wit It, Rock Wit ItDem Franchize Boyz Featuring Lil Peanut & Charlay | 9 | Chart history → |
| 8 | I'm N Luv (Wit A Stripper)T-Pain Featuring Mike Jones | 6 | Chart history → |
| 9 | Yo (Excuse Me Miss)Chris Brown | 10 | Chart history → |
| 10 | Check On ItBeyonce Featuring Slim Thug | 8 | Chart history → |
| 11 | Everytime We TouchCascada | 12 | Chart history → |
| 12 | GrillzNelly Featuring Paul Wall, Ali & Gipp | 11 | Chart history → |
| 13 | Ms. New BootyBubba Sparxxx Featuring Ying Yang Twins & Mr. ColliPark | 14 | Chart history → |
| 14 | BeepThe Pussycat Dolls Featuring will.i.am | 16 | Chart history → |
| 15 | Shake ThatEminem Featuring Nate Dogg | 13 | Chart history → |
| 16 | Walk AwayKelly Clarkson | 19 | Chart history → |
| 17 | Dance, DanceFall Out Boy | 17 | Chart history → |
| 18 | Touch ItBusta Rhymes | 18 | Chart history → |
| 19 | UnpredictableJamie Foxx Featuring Ludacris | 15 | Chart history → |
| 20 | LoveKeyshia Cole | 23 | Chart history → |
| 21 | Dirty Little SecretThe All-American Rejects | 21 | Chart history → |
| 22 | Because Of YouKelly Clarkson | 26 | Chart history → |
| 23 | Fresh AzimizBow Wow Featuring J-Kwon & Jermaine Dupri | 29 | Chart history → |
| 24 | Jesus, Take The WheelCarrie Underwood | 20 | Chart history → |
| 25 | Who Says You Can't Go HomeBon Jovi | 32 | Chart history → |
| 26 | Pump ItThe Black Eyed Peas | 24 | Chart history → |
| 27 | Ridin'Chamillionaire Featuring Krayzie Bone | 36 | Chart history → |
| 28 | My HumpsThe Black Eyed Peas | 25 | Chart history → |
| 29 | RompeDaddy Yankee | 30 | Chart history → |
| 30 | King Without A CrownMatisyahu | 28 | Chart history → |
| 31 | Stupid GirlsP!nk | 22 | Chart history → |
| 32 | Move AlongThe All-American Rejects | 51 | Chart history → |
| 33 | Run It!Chris Brown | 27 | Chart history → |
| 34 | StickwituThe Pussycat Dolls | 31 | Chart history → |
| 35 | Tell Me When To GoE-40 Featuring Keak Da Sneak | 58 | Chart history → |
| 36 | Tonight I Wanna CryKeith Urban | 37 | Chart history → |
| 37 | Sugar, We're Goin' DownFall Out Boy | 38 | Chart history → |
| 38 | SOSRihanna | 44 | Chart history → |
| 39 | Gold DiggerKanye West Featuring Jamie Foxx | 34 | Chart history → |
| 40 | PhotographNickelback | 35 | Chart history → |
| 41 | World Wide SuicidePearl Jam | — | Chart history → |
| 42 | Savin' MeNickelback | 75 | Chart history → |
| 43 | Poppin' My CollarThree 6 Mafia | 52 | Chart history → |
| 44 | For You I Will (Confidence)Teddy Geiger | 53 | Chart history → |
| 45 | You And MeLifehouse | 39 | Chart history → |
| 46 | What Hurts The MostRascal Flatts | 49 | Chart history → |
| 47 | Touch The SkyKanye West Featuring Lupe Fiasco | 42 | Chart history → |
| 48 | Over My Head (Cable Car)The Fray | 56 | Chart history → |
| 49 | Living In Fast ForwardKenny Chesney | 55 | Chart history → |
| 50 | Feel Good IncGorillaz | 43 | Chart history → |
| 51 | Your ManJosh Turner | 45 | Chart history → |
| 52 | Girl Next DoorSaving Jane | 54 | Chart history → |
| 53 | Ever The SameRob Thomas | 57 | Chart history → |
| 54 | What You KnowT.I. | 65 | Chart history → |
| 55 | When I Get Where I'm GoingBrad Paisley Featuring Dolly Parton | 46 | Chart history → |
| 56 | Best Friend50 Cent & Olivia | 60 | Chart history → |
| 57 | I Write Sins Not TragediesPanic! At The Disco | 82 | Chart history → |
| 58 | RodeoJuvenile | 41 | Chart history → |
| 59 | Upside DownJack Johnson | 59 | Chart history → |
| 60 | Get Drunk And Be SomebodyToby Keith | 63 | Chart history → |
| 61 | RushAly & AJ | 62 | Chart history → |
| 62 | She Don't Tell Me ToMontgomery Gentry | 68 | Chart history → |
| 63 | Looking For YouKirk Franklin | 71 | Chart history → |
| 64 | Nobody But MeBlake Shelton | 72 | Chart history → |
| 65 | BelieveBrooks & Dunn | 67 | Chart history → |
| 66 | When You're MadNe-Yo | 81 | Chart history → |
| 67 | L.O.V.E.Ashlee Simpson | 61 | Chart history → |
| 68 | GirlPaul Wall | 83 | Chart history → |
| 69 | Cheatin'Sara Evans | 76 | Chart history → |
| 70 | What's Left Of MeNick Lachey | 73 | Chart history → |
| 71 | Goodbye My LoverJames Blunt | 66 | Chart history → |
| 72 | WhyJason Aldean | 88 | Chart history → |
| 73 | Oh Yes (aka 'Postman')Juelz Santana | 74 | Chart history → |
| 74 | Always On Your SideSheryl Crow & Sting | 33 | Chart history → |
| 75 | The Real ThingBo Bice | 98 | Chart history → |
| 76 | Perfect SituationWeezer | 69 | Chart history → |
| 77 | SorryMadonna | 77 | Chart history → |
| 78 | In My MindHeather Headley | 89 | Chart history → |
| 79 | Can't Let GoAnthony Hamilton | 86 | Chart history → |
| 80 | Breaking FreeZac Efron, Andrew Seeley & Vanessa Anne Hudgens | 79 | Chart history → |
| 81 | 4 MinutesAvant | 94 | Chart history → |
| 82 | Gotta GoTrey Songz | 70 | Chart history → |
| 83 | Lights And SoundsYellowcard | 78 | Chart history → |
| 84 | Hips Don't LieShakira Featuring Wyclef Jean | — | Chart history → |
| 85 | Black Horse & The Cherry TreeKT Tunstall | 91 | Chart history → |
| 86 | Bring Out The Freak In YouLil Rob | 85 | Chart history → |
| 87 | Betcha Can't Do It Like MeD4L | 80 | Chart history → |
| 88 | The Only Difference Between Martyrdom And Suicide Is Press CoveragePanic! At The Disco | — | Chart history → |
| 89 | Settle For A SlowdownDierks Bentley | — | Chart history → |
| 90 | KeroseneMiranda Lambert | 87 | Chart history → |
| 91 | Wherever You AreJack Ingram | 97 | Chart history → |
| 92 | Something's Gotta GiveLeAnn Rimes | 100 | Chart history → |
| 93 | Conceited (There's Something About Remy)Remy Ma | — | Chart history → |
| 94 | Wasteland10 Years | — | Chart history → |
| 95 | Kryptonite (I'm On It)Purple Ribbon All-Stars | 93 | Chart history → |
| 96 | Gettin' SomeShawnna | — | Chart history → |
| 97 | Gold LionYeah Yeah Yeahs | — | Chart history → |
| 98 | My HoodYoung Jeezy | 92 | Chart history → |
| 99 | TalkColdplay | 99 | Chart history → |
| 100 | CrashGwen Stefani | 84 | Chart history → |