| 1 | SexyBackJustin Timberlake | 1 | Listen & explore → |
| 2 | Money MakerLudacris Featuring Pharrell | 2 | Chart history → |
| 3 | Lips Of An AngelHinder | 5 | Chart history → |
| 4 | How To Save A LifeThe Fray | 3 | Chart history → |
| 5 | Chasing CarsSnow Patrol | 6 | Chart history → |
| 6 | London BridgeFergie | 4 | Chart history → |
| 7 | Smack ThatAkon Featuring Eminem | 95 | Chart history → |
| 8 | Chain Hang LowJibbs | 8 | Chart history → |
| 9 | Far AwayNickelback | 11 | Chart history → |
| 10 | Pullin' Me BackChingy Featuring Tyrese | 9 | Chart history → |
| 11 | ButtonsThe Pussycat Dolls Featuring Snoop Dogg | 10 | Chart history → |
| 12 | Call Me When You're SoberEvanescence | 16 | Chart history → |
| 13 | Sexy LoveNe-Yo | 12 | Chart history → |
| 14 | Too Little Too LateJoJo | 7 | Chart history → |
| 15 | Say GoodbyeChris Brown | 26 | Chart history → |
| 16 | My LoveJustin Timberlake Featuring T.I. | 25 | Chart history → |
| 17 | Show StopperDanity Kane | 18 | Chart history → |
| 18 | Ring The AlarmBeyonce | 14 | Chart history → |
| 19 | I Know You See ItYung Joc Featuring Brandy 'Ms. B.' Hambrick | 17 | Chart history → |
| 20 | CrazyGnarls Barkley | 15 | Listen & explore → |
| 21 | (When You Gonna) Give It Up To MeSean Paul Feat. Keyshia Cole | 13 | Chart history → |
| 22 | Waiting On The World To ChangeJohn Mayer | 20 | Chart history → |
| 23 | PromiscuousNelly Furtado Featuring Timbaland | 19 | Chart history → |
| 24 | Over My Head (Cable Car)The Fray | 22 | Chart history → |
| 25 | Get UpCiara Featuring Chamillionaire | 27 | Chart history → |
| 26 | I Write Sins Not TragediesPanic! At The Disco | 21 | Chart history → |
| 27 | U And DatE-40 Featuring T-Pain & Kandi Girl | 23 | Chart history → |
| 28 | White & Nerdy"Weird Al" Yankovic | — | Chart history → |
| 29 | Come To MeDiddy Featuring Nicole Scherzinger | 30 | Chart history → |
| 30 | ManeaterNelly Furtado | 37 | Chart history → |
| 31 | Shoulder LeanYoung Dro Featuring T.I. | 24 | Chart history → |
| 32 | When You Were YoungThe Killers | 51 | Chart history → |
| 33 | Ain't No Other ManChristina Aguilera | 28 | Chart history → |
| 34 | Me & UCassie | 29 | Chart history → |
| 35 | What Hurts The MostRascal Flatts | 33 | Chart history → |
| 36 | Hate MeBlue October | 31 | Chart history → |
| 37 | I Loved Her FirstHeartland | 39 | Chart history → |
| 38 | Before He CheatsCarrie Underwood | 48 | Chart history → |
| 39 | Move AlongThe All-American Rejects | 32 | Chart history → |
| 40 | S.E.X.Lyfe Jennings | 38 | Chart history → |
| 41 | Call On MeJanet & Nelly | 36 | Chart history → |
| 42 | Hips Don't LieShakira Featuring Wyclef Jean | 35 | Chart history → |
| 43 | GalleryMario Vazquez | 49 | Chart history → |
| 44 | Would You Go With MeJosh Turner | 45 | Chart history → |
| 45 | It's Goin' DownYung Joc | 42 | Chart history → |
| 46 | That GirlFrankie J Featuring Mannie Fresh & Chamillionaire | 43 | Chart history → |
| 47 | Snap Yo FingersLil Jon Featuring E-40 & Sean Paul Of The YoungBloodZ | 44 | Chart history → |
| 48 | Want ToSugarland | 41 | Chart history → |
| 49 | Dani CaliforniaRed Hot Chili Peppers | 46 | Chart history → |
| 50 | Black Horse & The Cherry TreeKT Tunstall | 47 | Chart history → |
| 51 | Chicken Noodle Soup.Webstar & Young B Featuring The Voice Of Harlem | 66 | Chart history → |
| 52 | You Save MeKenny Chesney | 55 | Chart history → |
| 53 | Tell Me BabyRed Hot Chili Peppers | 54 | Chart history → |
| 54 | Leave The PiecesThe Wreckers | 52 | Chart history → |
| 55 | Once In A LifetimeKeith Urban | 56 | Chart history → |
| 56 | My WishRascal Flatts | 67 | Chart history → |
| 57 | Everytime Tha Beat DropMonica Featuring Dem Franchize Boyz | 62 | Chart history → |
| 58 | The RiddleFive For Fighting | 59 | Chart history → |
| 59 | Walk It OutUnk | 75 | Chart history → |
| 60 | Suddenly I SeeKT Tunstall | 80 | Chart history → |
| 61 | Every Mile A MemoryDierks Bentley | 65 | Chart history → |
| 62 | Right Where You Want MeJesse McCartney | 34 | Chart history → |
| 63 | About UsBrooke Hogan Featuring Paul Wall | 61 | Chart history → |
| 64 | Life Is A HighwayRascal Flatts | 60 | Chart history → |
| 65 | Stuntin' Like My DaddyBirdman & Lil Wayne | 70 | Chart history → |
| 66 | Here It Goes AgainOK Go | 53 | Chart history → |
| 67 | Brand New GirlfriendSteve Holy | 58 | Chart history → |
| 68 | I Call It LoveLionel Richie | 63 | Chart history → |
| 69 | Chemicals ReactAly & AJ | 50 | Chart history → |
| 70 | Building BridgesBrooks & Dunn With Sheryl Crow & Vince Gill | 71 | Chart history → |
| 71 | Remember The NameFort Minor Featuring Styles Of Beyond | 73 | Chart history → |
| 72 | Tim McGrawTaylor Swift | 77 | Chart history → |
| 73 | Push ItRick Ross | 74 | Chart history → |
| 74 | Money In The BankLil Scrappy Featuring Young Buck | 83 | Chart history → |
| 75 | If You're Going Through Hell (Before The Devil Even Knows)Rodney Atkins | 68 | Chart history → |
| 76 | Put Your Records OnCorinne Bailey Rae | 64 | Chart history → |
| 77 | My Little GirlTim McGraw | 85 | Chart history → |
| 78 | FergaliciousFergie | 79 | Chart history → |
| 79 | Give It AwayGeorge Strait | 69 | Chart history → |
| 80 | Like Red On A RoseAlan Jackson | 96 | Chart history → |
| 81 | It's Okay (One Blood)The Game Featuring Junior Reid | 86 | Chart history → |
| 82 | Deja VuBeyonce Featuring Jay Z | 57 | Chart history → |
| 83 | Need A BossShareefa Featuring Ludacris | 84 | Chart history → |
| 84 | Take Me As I AmMary J. Blige | 97 | Chart history → |
| 85 | The Kill (Bury Me)30 Seconds To Mars | 81 | Chart history → |
| 86 | Welcome To The Black ParadeMy Chemical Romance | 92 | Chart history → |
| 87 | Through GlassStone Sour | 78 | Chart history → |
| 88 | Come Back To MeVanessa Hudgens | 82 | Chart history → |
| 89 | The Diary Of JaneBreaking Benjamin | 88 | Chart history → |
| 90 | So ExcitedJanet Featuring Khia | — | Chart history → |
| 91 | Streetcorner SymphonyRob Thomas | 76 | Chart history → |
| 92 | Animal I Have BecomeThree Days Grace | 87 | Chart history → |
| 93 | Nothing Left To LoseMat Kearney | 93 | Chart history → |
| 94 | RockstarNickelback | — | Chart history → |
| 95 | I Wanna Love YouAkon Featuring Snoop Dogg | — | Chart history → |
| 96 | Face DownThe Red Jumpsuit Apparatus | 94 | Chart history → |
| 97 | It Ends TonightThe All-American Rejects | — | Chart history → |
| 98 | UnappreciatedCherish | — | Chart history → |
| 99 | I Can't Hate You AnymoreNick Lachey | 90 | Chart history → |
| 100 | HurtChristina Aguilera | — | Chart history → |