| 1 | SexyBackJustin Timberlake | 1 | Listen & explore → |
| 2 | Money MakerLudacris Featuring Pharrell | 2 | Chart history → |
| 3 | Lips Of An AngelHinder | 3 | Chart history → |
| 4 | Smack ThatAkon Featuring Eminem | 7 | Chart history → |
| 5 | How To Save A LifeThe Fray | 4 | Chart history → |
| 6 | Chasing CarsSnow Patrol | 5 | Chart history → |
| 7 | Chain Hang LowJibbs | 8 | Chart history → |
| 8 | Too Little Too LateJoJo | 14 | Chart history → |
| 9 | White & Nerdy"Weird Al" Yankovic | 28 | Chart history → |
| 10 | Far AwayNickelback | 9 | Chart history → |
| 11 | London BridgeFergie | 6 | Chart history → |
| 12 | Call Me When You're SoberEvanescence | 12 | Chart history → |
| 13 | My LoveJustin Timberlake Featuring T.I. | 16 | Chart history → |
| 14 | When You Were YoungThe Killers | 32 | Chart history → |
| 15 | Pullin' Me BackChingy Featuring Tyrese | 10 | Chart history → |
| 16 | Show StopperDanity Kane | 17 | Chart history → |
| 17 | Say GoodbyeChris Brown | 15 | Chart history → |
| 18 | ButtonsThe Pussycat Dolls Featuring Snoop Dogg | 11 | Chart history → |
| 19 | ManeaterNelly Furtado | 30 | Chart history → |
| 20 | Ring The AlarmBeyonce | 18 | Chart history → |
| 21 | Get UpCiara Featuring Chamillionaire | 25 | Chart history → |
| 22 | I Know You See ItYung Joc Featuring Brandy 'Ms. B.' Hambrick | 19 | Chart history → |
| 23 | CrazyGnarls Barkley | 20 | Listen & explore → |
| 24 | Sexy LoveNe-Yo | 13 | Chart history → |
| 25 | Over My Head (Cable Car)The Fray | 24 | Chart history → |
| 26 | (When You Gonna) Give It Up To MeSean Paul Feat. Keyshia Cole | 21 | Chart history → |
| 27 | Waiting On The World To ChangeJohn Mayer | 22 | Chart history → |
| 28 | Come To MeDiddy Featuring Nicole Scherzinger | 29 | Chart history → |
| 29 | I Write Sins Not TragediesPanic! At The Disco | 26 | Chart history → |
| 30 | PromiscuousNelly Furtado Featuring Timbaland | 23 | Chart history → |
| 31 | U And DatE-40 Featuring T-Pain & Kandi Girl | 27 | Chart history → |
| 32 | Shoulder LeanYoung Dro Featuring T.I. | 31 | Chart history → |
| 33 | Before He CheatsCarrie Underwood | 38 | Chart history → |
| 34 | What Hurts The MostRascal Flatts | 35 | Chart history → |
| 35 | Give It AwayGeorge Strait | 79 | Chart history → |
| 36 | I Loved Her FirstHeartland | 37 | Chart history → |
| 37 | S.E.X.Lyfe Jennings | 40 | Chart history → |
| 38 | Ain't No Other ManChristina Aguilera | 33 | Chart history → |
| 39 | Hate MeBlue October | 36 | Chart history → |
| 40 | GalleryMario Vazquez | 43 | Chart history → |
| 41 | Move AlongThe All-American Rejects | 39 | Chart history → |
| 42 | Me & UCassie | 34 | Chart history → |
| 43 | Would You Go With MeJosh Turner | 44 | Chart history → |
| 44 | Hips Don't LieShakira Featuring Wyclef Jean | 42 | Chart history → |
| 45 | Chicken Noodle Soup.Webstar & Young B Featuring The Voice Of Harlem | 51 | Chart history → |
| 46 | It's Goin' DownYung Joc | 45 | Chart history → |
| 47 | Walk It OutUnk | 59 | Chart history → |
| 48 | Everytime Tha Beat DropMonica Featuring Dem Franchize Boyz | 57 | Chart history → |
| 49 | That GirlFrankie J Featuring Mannie Fresh & Chamillionaire | 46 | Chart history → |
| 50 | You Save MeKenny Chesney | 52 | Chart history → |
| 51 | Want ToSugarland | 48 | Chart history → |
| 52 | My WishRascal Flatts | 56 | Chart history → |
| 53 | Call On MeJanet & Nelly | 41 | Chart history → |
| 54 | Once In A LifetimeKeith Urban | 55 | Chart history → |
| 55 | FergaliciousFergie | 78 | Chart history → |
| 56 | Stuntin' Like My DaddyBirdman & Lil Wayne | 65 | Chart history → |
| 57 | My Little GirlTim McGraw | 77 | Chart history → |
| 58 | Every Mile A MemoryDierks Bentley | 61 | Chart history → |
| 59 | Tell Me BabyRed Hot Chili Peppers | 53 | Chart history → |
| 60 | About UsBrooke Hogan Featuring Paul Wall | 63 | Chart history → |
| 61 | Push ItRick Ross | 73 | Chart history → |
| 62 | I Call It LoveLionel Richie | 68 | Chart history → |
| 63 | The RiddleFive For Fighting | 58 | Chart history → |
| 64 | Right Where You Want MeJesse McCartney | 62 | Chart history → |
| 65 | Money In The BankLil Scrappy Featuring Young Buck | 74 | Chart history → |
| 66 | Leave The PiecesThe Wreckers | 54 | Chart history → |
| 67 | Need A BossShareefa Featuring Ludacris | 83 | Chart history → |
| 68 | Tim McGrawTaylor Swift | 72 | Chart history → |
| 69 | Life Is A HighwayRascal Flatts | 64 | Chart history → |
| 70 | Remember The NameFort Minor Featuring Styles Of Beyond | 71 | Chart history → |
| 71 | Put Your Records OnCorinne Bailey Rae | 76 | Chart history → |
| 72 | Suddenly I SeeKT Tunstall | 60 | Chart history → |
| 73 | Take Me As I AmMary J. Blige | 84 | Chart history → |
| 74 | Here It Goes AgainOK Go | 66 | Chart history → |
| 75 | HurtChristina Aguilera | 100 | Chart history → |
| 76 | It's Okay (One Blood)The Game Featuring Junior Reid | 81 | Chart history → |
| 77 | Brand New GirlfriendSteve Holy | 67 | Chart history → |
| 78 | Welcome To The Black ParadeMy Chemical Romance | 86 | Chart history → |
| 79 | I Wanna Love YouAkon Featuring Snoop Dogg | 95 | Chart history → |
| 80 | Shortie Like MineBow Wow Featuring Chris Brown & Johnta Austin | — | Chart history → |
| 81 | Through GlassStone Sour | 87 | Chart history → |
| 82 | Canadian Idiot"Weird Al" Yankovic | — | Chart history → |
| 83 | Building BridgesBrooks & Dunn With Sheryl Crow & Vince Gill | 70 | Chart history → |
| 84 | It Ends TonightThe All-American Rejects | 97 | Chart history → |
| 85 | Like Red On A RoseAlan Jackson | 80 | Chart history → |
| 86 | The Kill (Bury Me)30 Seconds To Mars | 85 | Chart history → |
| 87 | We Fly HighJim Jones | — | Chart history → |
| 88 | BostonAugustana | — | Chart history → |
| 89 | The Diary Of JaneBreaking Benjamin | 89 | Chart history → |
| 90 | Show Me What You GotJAY-Z | — | Chart history → |
| 91 | Come Back To MeVanessa Hudgens | 88 | Chart history → |
| 92 | RockstarNickelback | 94 | Chart history → |
| 93 | UnappreciatedCherish | 98 | Chart history → |
| 94 | I Can't Hate You AnymoreNick Lachey | 99 | Chart history → |
| 95 | Walk Away (Remember Me)Paula DeAnda Featuring The DEY | — | Chart history → |
| 96 | She's EverythingBrad Paisley | — | Chart history → |
| 97 | Face DownThe Red Jumpsuit Apparatus | 96 | Chart history → |
| 98 | Chemicals ReactAly & AJ | 69 | Chart history → |
| 99 | Deja VuBeyonce Featuring Jay Z | 82 | Chart history → |
| 100 | So ExcitedJanet Featuring Khia | 90 | Chart history → |