| 1 | IrreplaceableBeyonce | 1 | Chart history → |
| 2 | Say It RightNelly Furtado | 3 | Listen & explore → |
| 3 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 2 | Chart history → |
| 4 | It's Not OverDaughtry | 4 | Chart history → |
| 5 | The Sweet EscapeGwen Stefani Featuring Akon | 6 | Chart history → |
| 6 | Runaway LoveLudacris Featuring Mary J. Blige | 7 | Chart history → |
| 7 | I Wanna Love YouAkon Featuring Snoop Dogg | 5 | Chart history → |
| 8 | We Fly HighJim Jones | 8 | Chart history → |
| 9 | YouLloyd Featuring Lil Wayne | 11 | Chart history → |
| 10 | Walk It OutUnk | 17 | Chart history → |
| 11 | What Goes Around...Comes AroundJustin Timberlake | 10 | Chart history → |
| 12 | On The HotlinePretty Ricky | 12 | Chart history → |
| 13 | Make It RainFat Joe Featuring Lil Wayne | 15 | Chart history → |
| 14 | Here (In Your Arms)Hellogoodbye | 19 | Chart history → |
| 15 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 28 | Chart history → |
| 16 | FergaliciousFergie | 9 | Chart history → |
| 17 | How To Save A LifeThe Fray | 14 | Chart history → |
| 18 | Smack ThatAkon Featuring Eminem | 13 | Chart history → |
| 19 | Ice BoxOmarion | 20 | Chart history → |
| 20 | Welcome To The Black ParadeMy Chemical Romance | 18 | Chart history → |
| 21 | My LoveJustin Timberlake Featuring T.I. | 16 | Chart history → |
| 22 | PromiseCiara | 23 | Chart history → |
| 23 | Suddenly I SeeKT Tunstall | 21 | Chart history → |
| 24 | Walk Away (Remember Me)Paula DeAnda Featuring The DEY | 24 | Chart history → |
| 25 | Waiting On The World To ChangeJohn Mayer | 22 | Chart history → |
| 26 | Lips Of An AngelHinder | 27 | Chart history → |
| 27 | Shortie Like MineBow Wow Featuring Chris Brown & Johnta Austin | 26 | Chart history → |
| 28 | It Ends TonightThe All-American Rejects | 25 | Chart history → |
| 29 | Lost Without URobin Thicke | 37 | Chart history → |
| 30 | Don't MatterAkon | 57 | Chart history → |
| 31 | GlamorousFergie Featuring Ludacris | 51 | Chart history → |
| 32 | If Everyone CaredNickelback | 38 | Chart history → |
| 33 | Chasing CarsSnow Patrol | 30 | Chart history → |
| 34 | Snow ((Hey Oh))Red Hot Chili Peppers | 31 | Chart history → |
| 35 | SexyBackJustin Timberlake | 32 | Listen & explore → |
| 36 | Far AwayNickelback | 34 | Chart history → |
| 37 | Before He CheatsCarrie Underwood | 35 | Chart history → |
| 38 | BostonAugustana | 40 | Chart history → |
| 39 | Keep Holding OnAvril Lavigne | 33 | Chart history → |
| 40 | Year 3000Jonas Brothers | — | Chart history → |
| 41 | Watching YouRodney Atkins | 36 | Chart history → |
| 42 | Poppin'Chris Brown Featuring Jay Biz | 48 | Chart history → |
| 43 | Face DownThe Red Jumpsuit Apparatus | 45 | Chart history → |
| 44 | That's ThatSnoop Dogg Featuring R. Kelly | 39 | Chart history → |
| 45 | Break It OffRihanna & Sean Paul | 52 | Chart history → |
| 46 | Top BackT.I. | 54 | Chart history → |
| 47 | Stupid BoyKeith Urban | 47 | Chart history → |
| 48 | Over ItKatharine McPhee | — | Chart history → |
| 49 | Throw Some D'sRich Boy Featuring Polow Da Don | 59 | Chart history → |
| 50 | Nothing Left To LoseMat Kearney | 41 | Chart history → |
| 51 | She's EverythingBrad Paisley | 46 | Chart history → |
| 52 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 60 | Chart history → |
| 53 | HurtChristina Aguilera | 43 | Chart history → |
| 54 | SmileLily Allen | 83 | Chart history → |
| 55 | Tell MeDiddy Featuring Christina Aguilera | 56 | Chart history → |
| 56 | Push It To The LimitCorbin Bleu | 29 | Chart history → |
| 57 | Into The OceanBlue October | 58 | Chart history → |
| 58 | I Luv ItYoung Jeezy | 49 | Chart history → |
| 59 | This Is Why I'm HotMims | 72 | Chart history → |
| 60 | Wait A MinuteThe Pussycat Dolls Featuring Timbaland | 50 | Chart history → |
| 61 | DashboardModest Mouse | — | Chart history → |
| 62 | King KongJibbs Featuring Chamillionaire | 71 | Chart history → |
| 63 | PainThree Days Grace | 63 | Chart history → |
| 64 | Last NightDiddy Featuring Keyshia Cole | 74 | Chart history → |
| 65 | Wind It UpGwen Stefani | 55 | Chart history → |
| 66 | It Just Comes NaturalGeorge Strait | 61 | Chart history → |
| 67 | Say OKVanessa Hudgens | — | Chart history → |
| 68 | Alyssa LiesJason Michael Carroll | 70 | Chart history → |
| 69 | FidelityRegina Spektor | 53 | Chart history → |
| 70 | Ladies Love Country BoysTrace Adkins | 66 | Chart history → |
| 71 | RockstarNickelback | 64 | Chart history → |
| 72 | Amarillo SkyJason Aldean | 62 | Chart history → |
| 73 | Go GettaYoung Jeezy Featuring R. Kelly | 77 | Chart history → |
| 74 | She's Like The WindLumidee Featuring Tony Sunshine | 80 | Chart history → |
| 75 | ZoomLil' Boosie Featuring Yung Joc | 69 | Chart history → |
| 76 | White & Nerdy"Weird Al" Yankovic | 65 | Chart history → |
| 77 | Lips Of An AngelJack Ingram | — | Chart history → |
| 78 | Red High HeelsKellie Pickler | 67 | Chart history → |
| 79 | And I Am Telling You I'm Not GoingJennifer Hudson | 79 | Chart history → |
| 80 | Little Bit Of LifeCraig Morgan | 81 | Chart history → |
| 81 | Grace KellyMIKA | — | Chart history → |
| 82 | Thinking About YouNorah Jones | — | Chart history → |
| 83 | Crazy CarThe Naked Brothers Band | — | Chart history → |
| 84 | ListenBeyonce | 75 | Chart history → |
| 85 | Streetcorner SymphonyRob Thomas | 82 | Chart history → |
| 86 | Want ToSugarland | 78 | Chart history → |
| 87 | From Yesterday30 Seconds To Mars | 84 | Chart history → |
| 88 | Famous Last WordsMy Chemical Romance | 93 | Chart history → |
| 89 | Hillbilly DeluxeBrooks & Dunn | 92 | Chart history → |
| 90 | Beer In MexicoKenny Chesney | 98 | Chart history → |
| 91 | BuddyMusiq Soulchild | 100 | Chart history → |
| 92 | Wouldn't Get FarThe Game Featuring Kanye West | — | Chart history → |
| 93 | One Wing In The FireTrent Tomlinson | 90 | Chart history → |
| 94 | WastedCarrie Underwood | — | Chart history → |
| 95 | Jump To The RhythmJordan Pruitt | 73 | Chart history → |
| 96 | Be Good To MeAshley Tisdale | — | Chart history → |
| 97 | Settlin'Sugarland | — | Chart history → |
| 98 | I'll Wait For YouJoe Nichols | — | Chart history → |
| 99 | AnywayMartina McBride | — | Chart history → |
| 100 | U + Ur HandP!nk | 95 | Chart history → |