| 1 | Say It RightNelly Furtado | 2 | Listen & explore → |
| 2 | IrreplaceableBeyonce | 1 | Chart history → |
| 3 | The Sweet EscapeGwen Stefani Featuring Akon | 5 | Chart history → |
| 4 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 3 | Chart history → |
| 5 | Runaway LoveLudacris Featuring Mary J. Blige | 6 | Chart history → |
| 6 | It's Not OverDaughtry | 4 | Chart history → |
| 7 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 15 | Chart history → |
| 8 | What Goes Around...Comes AroundJustin Timberlake | 11 | Chart history → |
| 9 | GlamorousFergie Featuring Ludacris | 31 | Chart history → |
| 10 | I Wanna Love YouAkon Featuring Snoop Dogg | 7 | Chart history → |
| 11 | Don't MatterAkon | 30 | Chart history → |
| 12 | YouLloyd Featuring Lil Wayne | 9 | Chart history → |
| 13 | Walk It OutUnk | 10 | Chart history → |
| 14 | We Fly HighJim Jones | 8 | Chart history → |
| 15 | Make It RainFat Joe Featuring Lil Wayne | 13 | Chart history → |
| 16 | On The HotlinePretty Ricky | 12 | Chart history → |
| 17 | Here (In Your Arms)Hellogoodbye | 14 | Chart history → |
| 18 | Ice BoxOmarion | 19 | Chart history → |
| 19 | FergaliciousFergie | 16 | Chart history → |
| 20 | My LoveJustin Timberlake Featuring T.I. | 21 | Chart history → |
| 21 | Smack ThatAkon Featuring Eminem | 18 | Chart history → |
| 22 | How To Save A LifeThe Fray | 17 | Chart history → |
| 23 | Welcome To The Black ParadeMy Chemical Romance | 20 | Chart history → |
| 24 | Waiting On The World To ChangeJohn Mayer | 25 | Chart history → |
| 25 | Lost Without URobin Thicke | 29 | Chart history → |
| 26 | PromiseCiara | 22 | Chart history → |
| 27 | Walk Away (Remember Me)Paula DeAnda Featuring The DEY | 24 | Chart history → |
| 28 | Lips Of An AngelHinder | 26 | Chart history → |
| 29 | Snow ((Hey Oh))Red Hot Chili Peppers | 34 | Chart history → |
| 30 | SexyBackJustin Timberlake | 35 | Listen & explore → |
| 31 | It Ends TonightThe All-American Rejects | 28 | Chart history → |
| 32 | Suddenly I SeeKT Tunstall | 23 | Chart history → |
| 33 | Chasing CarsSnow Patrol | 33 | Chart history → |
| 34 | Top BackT.I. | 46 | Chart history → |
| 35 | Shortie Like MineBow Wow Featuring Chris Brown & Johnta Austin | 27 | Chart history → |
| 36 | Before He CheatsCarrie Underwood | 37 | Chart history → |
| 37 | Keep Holding OnAvril Lavigne | 39 | Chart history → |
| 38 | BostonAugustana | 38 | Chart history → |
| 39 | If Everyone CaredNickelback | 32 | Chart history → |
| 40 | Face DownThe Red Jumpsuit Apparatus | 43 | Chart history → |
| 41 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 52 | Chart history → |
| 42 | Poppin'Chris Brown Featuring Jay Biz | 42 | Chart history → |
| 43 | Stupid BoyKeith Urban | 47 | Chart history → |
| 44 | Watching YouRodney Atkins | 41 | Chart history → |
| 45 | Throw Some D'sRich Boy Featuring Polow Da Don | 49 | Chart history → |
| 46 | This Is Why I'm HotMims | 59 | Chart history → |
| 47 | Break It OffRihanna & Sean Paul | 45 | Chart history → |
| 48 | Far AwayNickelback | 36 | Chart history → |
| 49 | SmileLily Allen | 54 | Chart history → |
| 50 | She's EverythingBrad Paisley | 51 | Chart history → |
| 51 | Last NightDiddy Featuring Keyshia Cole | 64 | Chart history → |
| 52 | That's ThatSnoop Dogg Featuring R. Kelly | 44 | Chart history → |
| 53 | Into The OceanBlue October | 57 | Chart history → |
| 54 | Tell MeDiddy Featuring Christina Aguilera | 55 | Chart history → |
| 55 | BuddyMusiq Soulchild | 91 | Chart history → |
| 56 | King KongJibbs Featuring Chamillionaire | 62 | Chart history → |
| 57 | Nothing Left To LoseMat Kearney | 50 | Chart history → |
| 58 | She's Like The WindLumidee Featuring Tony Sunshine | 74 | Chart history → |
| 59 | HurtChristina Aguilera | 53 | Chart history → |
| 60 | Over ItKatharine McPhee | 48 | Chart history → |
| 61 | Say OKVanessa Hudgens | 67 | Chart history → |
| 62 | Go GettaYoung Jeezy Featuring R. Kelly | 73 | Chart history → |
| 63 | PainThree Days Grace | 63 | Chart history → |
| 64 | Alyssa LiesJason Michael Carroll | 68 | Chart history → |
| 65 | It Just Comes NaturalGeorge Strait | 66 | Chart history → |
| 66 | FidelityRegina Spektor | 69 | Chart history → |
| 67 | Ladies Love Country BoysTrace Adkins | 70 | Chart history → |
| 68 | Wind It UpGwen Stefani | 65 | Chart history → |
| 69 | Wait A MinuteThe Pussycat Dolls Featuring Timbaland | 60 | Chart history → |
| 70 | I Luv ItYoung Jeezy | 58 | Chart history → |
| 71 | Push It To The LimitCorbin Bleu | 56 | Chart history → |
| 72 | Amarillo SkyJason Aldean | 72 | Chart history → |
| 73 | Wouldn't Get FarThe Game Featuring Kanye West | 92 | Chart history → |
| 74 | White & Nerdy"Weird Al" Yankovic | 76 | Chart history → |
| 75 | Little Bit Of LifeCraig Morgan | 80 | Chart history → |
| 76 | From Yesterday30 Seconds To Mars | 87 | Chart history → |
| 77 | Outside Looking InJordan Pruitt | — | Chart history → |
| 78 | Not Fade AwaySheryl Crow | — | Chart history → |
| 79 | ZoomLil' Boosie Featuring Yung Joc | 75 | Chart history → |
| 80 | Be Good To MeAshley Tisdale | 96 | Chart history → |
| 81 | And I Am Telling You I'm Not GoingJennifer Hudson | 79 | Chart history → |
| 82 | WastedCarrie Underwood | 94 | Chart history → |
| 83 | Red High HeelsKellie Pickler | 78 | Chart history → |
| 84 | Beer In MexicoKenny Chesney | 90 | Chart history → |
| 85 | Settlin'Sugarland | 97 | Chart history → |
| 86 | Grace KellyMIKA | 81 | Chart history → |
| 87 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | — | Chart history → |
| 88 | Streetcorner SymphonyRob Thomas | 85 | Chart history → |
| 89 | Hillbilly DeluxeBrooks & Dunn | 89 | Chart history → |
| 90 | CandymanChristina Aguilera | — | Chart history → |
| 91 | ListenBeyonce | 84 | Chart history → |
| 92 | I'll Wait For YouJoe Nichols | 98 | Chart history → |
| 93 | 1st TimeYung Joc Featuring Marques Houston & Trey Songz | — | Chart history → |
| 94 | 2 StepUnk | — | Chart history → |
| 95 | Famous Last WordsMy Chemical Romance | 88 | Chart history → |
| 96 | U + Ur HandP!nk | 100 | Chart history → |
| 97 | Thinking About YouNorah Jones | 82 | Chart history → |
| 98 | AnywayMartina McBride | 99 | Chart history → |
| 99 | DashboardModest Mouse | 61 | Chart history → |
| 100 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | — | Chart history → |