| 1 | What Goes Around...Comes AroundJustin Timberlake | 8 | Chart history → |
| 2 | Runaway LoveLudacris Featuring Mary J. Blige | 5 | Chart history → |
| 3 | Say It RightNelly Furtado | 1 | Listen & explore → |
| 4 | Not Ready To Make NiceDixie Chicks | — | Chart history → |
| 5 | Don't MatterAkon | 11 | Chart history → |
| 6 | The Sweet EscapeGwen Stefani Featuring Akon | 3 | Chart history → |
| 7 | It's Not OverDaughtry | 6 | Chart history → |
| 8 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 7 | Chart history → |
| 9 | IrreplaceableBeyonce | 2 | Chart history → |
| 10 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 4 | Chart history → |
| 11 | I Wanna Love YouAkon Featuring Snoop Dogg | 10 | Chart history → |
| 12 | YouLloyd Featuring Lil Wayne | 12 | Chart history → |
| 13 | Ice BoxOmarion | 18 | Chart history → |
| 14 | Waiting On The World To ChangeJohn Mayer | 24 | Chart history → |
| 15 | We Fly HighJim Jones | 14 | Chart history → |
| 16 | Make It RainFat Joe Featuring Lil Wayne | 15 | Chart history → |
| 17 | Walk It OutUnk | 13 | Chart history → |
| 18 | On The HotlinePretty Ricky | 16 | Chart history → |
| 19 | Here (In Your Arms)Hellogoodbye | 17 | Chart history → |
| 20 | My LoveJustin Timberlake Featuring T.I. | 20 | Chart history → |
| 21 | FergaliciousFergie | 19 | Chart history → |
| 22 | Snow ((Hey Oh))Red Hot Chili Peppers | 29 | Chart history → |
| 23 | Lost Without URobin Thicke | 25 | Chart history → |
| 24 | Smack ThatAkon Featuring Eminem | 21 | Chart history → |
| 25 | How To Save A LifeThe Fray | 22 | Chart history → |
| 26 | Welcome To The Black ParadeMy Chemical Romance | 23 | Chart history → |
| 27 | If Everyone CaredNickelback | 39 | Chart history → |
| 28 | SexyBackJustin Timberlake | 30 | Listen & explore → |
| 29 | Top BackT.I. | 34 | Chart history → |
| 30 | PromiseCiara | 26 | Chart history → |
| 31 | Walk Away (Remember Me)Paula DeAnda Featuring The DEY | 27 | Chart history → |
| 32 | This Is Why I'm HotMims | 46 | Chart history → |
| 33 | GlamorousFergie Featuring Ludacris | 9 | Chart history → |
| 34 | BostonAugustana | 38 | Chart history → |
| 35 | Before He CheatsCarrie Underwood | 36 | Chart history → |
| 36 | Chasing CarsSnow Patrol | 33 | Chart history → |
| 37 | It Ends TonightThe All-American Rejects | 31 | Chart history → |
| 38 | Keep Holding OnAvril Lavigne | 37 | Chart history → |
| 39 | Lips Of An AngelHinder | 28 | Chart history → |
| 40 | Face DownThe Red Jumpsuit Apparatus | 40 | Chart history → |
| 41 | Shortie Like MineBow Wow Featuring Chris Brown & Johnta Austin | 35 | Chart history → |
| 42 | Last NightDiddy Featuring Keyshia Cole | 51 | Chart history → |
| 43 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 41 | Chart history → |
| 44 | Poppin'Chris Brown Featuring Jay Biz | 42 | Chart history → |
| 45 | Stupid BoyKeith Urban | 43 | Chart history → |
| 46 | Go GettaYoung Jeezy Featuring R. Kelly | 62 | Chart history → |
| 47 | Suddenly I SeeKT Tunstall | 32 | Chart history → |
| 48 | AnywayMartina McBride | 98 | Chart history → |
| 49 | Throw Some D'sRich Boy Featuring Polow Da Don | 45 | Chart history → |
| 50 | She's Like The WindLumidee Featuring Tony Sunshine | 58 | Chart history → |
| 51 | Watching YouRodney Atkins | 44 | Chart history → |
| 52 | Break It OffRihanna & Sean Paul | 47 | Chart history → |
| 53 | Tell MeDiddy Featuring Christina Aguilera | 54 | Chart history → |
| 54 | King KongJibbs Featuring Chamillionaire | 56 | Chart history → |
| 55 | She's EverythingBrad Paisley | 50 | Chart history → |
| 56 | Like A StarCorinne Bailey Rae | — | Chart history → |
| 57 | Into The OceanBlue October | 53 | Chart history → |
| 58 | Year 3000Jonas Brothers | — | Chart history → |
| 59 | Nothing Left To LoseMat Kearney | 57 | Chart history → |
| 60 | That's ThatSnoop Dogg Featuring R. Kelly | 52 | Chart history → |
| 61 | FidelityRegina Spektor | 66 | Chart history → |
| 62 | Ladies Love Country BoysTrace Adkins | 67 | Chart history → |
| 63 | PainThree Days Grace | 63 | Chart history → |
| 64 | BuddyMusiq Soulchild | 55 | Chart history → |
| 65 | Alyssa LiesJason Michael Carroll | 64 | Chart history → |
| 66 | Over ItKatharine McPhee | 60 | Chart history → |
| 67 | SmileLily Allen | 49 | Chart history → |
| 68 | It Just Comes NaturalGeorge Strait | 65 | Chart history → |
| 69 | Say OKVanessa Hudgens | 61 | Chart history → |
| 70 | Wind It UpGwen Stefani | 68 | Chart history → |
| 71 | GravityJohn Mayer | — | Chart history → |
| 72 | Wouldn't Get FarThe Game Featuring Kanye West | 73 | Chart history → |
| 73 | High Maintenance WomanToby Keith | — | Chart history → |
| 74 | WastedCarrie Underwood | 82 | Chart history → |
| 75 | FlatheadThe Fratellis | — | Chart history → |
| 76 | Grace KellyMIKA | 86 | Chart history → |
| 77 | From Yesterday30 Seconds To Mars | 76 | Chart history → |
| 78 | CandymanChristina Aguilera | 90 | Chart history → |
| 79 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | 87 | Chart history → |
| 80 | Amarillo SkyJason Aldean | 72 | Chart history → |
| 81 | ListenBeyonce | 91 | Chart history → |
| 82 | Little Bit Of LifeCraig Morgan | 75 | Chart history → |
| 83 | Wait A MinuteThe Pussycat Dolls Featuring Timbaland | 69 | Chart history → |
| 84 | I Luv ItYoung Jeezy | 70 | Chart history → |
| 85 | Beer In MexicoKenny Chesney | 84 | Chart history → |
| 86 | Outside Looking InJordan Pruitt | 77 | Chart history → |
| 87 | 2 StepUnk | 94 | Chart history → |
| 88 | Save RoomJohn Legend | — | Chart history → |
| 89 | Push It To The LimitCorbin Bleu | 71 | Chart history → |
| 90 | I'm A FlirtR. Kelly Or Bow Wow (Featuring T.I. & T-Pain) | — | Chart history → |
| 91 | Read My MindThe Killers | — | Chart history → |
| 92 | Settlin'Sugarland | 85 | Chart history → |
| 93 | And I Am Telling You I'm Not GoingJennifer Hudson | 81 | Chart history → |
| 94 | Famous Last WordsMy Chemical Romance | 95 | Chart history → |
| 95 | I'll Wait For YouJoe Nichols | 92 | Chart history → |
| 96 | Hillbilly DeluxeBrooks & Dunn | 89 | Chart history → |
| 97 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | 100 | Chart history → |
| 98 | ZoomLil' Boosie Featuring Yung Joc | 79 | Chart history → |
| 99 | U + Ur HandP!nk | 96 | Chart history → |
| 100 | StandRascal Flatts | — | Chart history → |