| 1 | Give It To MeTimbaland Featuring Nelly Furtado & Justin Timberlake | 42 | Chart history → |
| 2 | Don't MatterAkon | 1 | Chart history → |
| 3 | The Sweet EscapeGwen Stefani Featuring Akon | 2 | Chart history → |
| 4 | GlamorousFergie Featuring Ludacris | 4 | Chart history → |
| 5 | This Is Why I'm HotMims | 3 | Chart history → |
| 6 | GirlfriendAvril Lavigne | 5 | Chart history → |
| 7 | What I've DoneLinkin Park | — | Chart history → |
| 8 | Cupid's Chokehold/Breakfast In AmericaGym Class Heroes Featuring Patrick Stump | 7 | Chart history → |
| 9 | Beautiful LiarBeyonce & Shakira | 6 | Chart history → |
| 10 | Buy U A Drank (Shawty Snappin')T-Pain Featuring Yung Joc | 14 | Chart history → |
| 11 | Last NightDiddy Featuring Keyshia Cole | 10 | Chart history → |
| 12 | It's Not OverDaughtry | 9 | Chart history → |
| 13 | What Goes Around...Comes AroundJustin Timberlake | 8 | Chart history → |
| 14 | U + Ur HandP!nk | 19 | Chart history → |
| 15 | I'm A FlirtR. Kelly Or Bow Wow (Featuring T.I. & T-Pain) | 15 | Chart history → |
| 16 | Say It RightNelly Furtado | 12 | Listen & explore → |
| 17 | Last Dollar (Fly Away)Tim McGraw | 13 | Chart history → |
| 18 | Go GettaYoung Jeezy Featuring R. Kelly | 18 | Chart history → |
| 19 | Lost Without URobin Thicke | 16 | Chart history → |
| 20 | If Everyone CaredNickelback | 21 | Chart history → |
| 21 | Throw Some D'sRich Boy Featuring Polow Da Don | 11 | Chart history → |
| 22 | Before He CheatsCarrie Underwood | 22 | Chart history → |
| 23 | Ice BoxOmarion | 17 | Chart history → |
| 24 | With LoveHilary Duff | 43 | Chart history → |
| 25 | Like A BoyCiara | 25 | Chart history → |
| 26 | The Way I LiveBaby Boy Da Prince Featuring Lil Boosie | 24 | Chart history → |
| 27 | Face DownThe Red Jumpsuit Apparatus | 26 | Chart history → |
| 28 | IrreplaceableBeyonce | 28 | Chart history → |
| 29 | This Ain't A Scene, It's An Arms RaceFall Out Boy | 20 | Chart history → |
| 30 | Pop, Lock & Drop ItHuey | 38 | Chart history → |
| 31 | 2 StepUnk | 30 | Chart history → |
| 32 | Make It RainFat Joe Featuring Lil Wayne | 27 | Chart history → |
| 33 | YouLloyd Featuring Lil Wayne | 23 | Chart history → |
| 34 | Over ItKatharine McPhee | 31 | Chart history → |
| 35 | CandymanChristina Aguilera | 29 | Chart history → |
| 36 | Rock Yo HipsCrime Mob Featuring Lil Scrappy | 34 | Chart history → |
| 37 | How To Save A LifeThe Fray | 33 | Chart history → |
| 38 | Walk It OutUnk | 32 | Chart history → |
| 39 | Outta My SystemBow Wow Featuring T-Pain & Johnta Austin | 44 | Chart history → |
| 40 | Better Than MeHinder | 50 | Chart history → |
| 41 | I Wanna Love YouAkon Featuring Snoop Dogg | 35 | Chart history → |
| 42 | WastedCarrie Underwood | 37 | Chart history → |
| 43 | HomeDaughtry | 51 | Chart history → |
| 44 | Get It ShawtyLloyd | 55 | Chart history → |
| 45 | BuddyMusiq Soulchild | 36 | Chart history → |
| 46 | Because Of YouNe-Yo | 54 | Chart history → |
| 47 | Waiting On The World To ChangeJohn Mayer | 45 | Chart history → |
| 48 | Smack ThatAkon Featuring Eminem | 41 | Chart history → |
| 49 | We Fly HighJim Jones | 49 | Chart history → |
| 50 | TicksBrad Paisley | 40 | Chart history → |
| 51 | Break It OffRihanna & Sean Paul | 47 | Chart history → |
| 52 | AnywayMartina McBride | 62 | Chart history → |
| 53 | She's Like The WindLumidee Featuring Tony Sunshine | 46 | Chart history → |
| 54 | Doe Boy FreshThree 6 Mafia Featuring Chamillionaire | 63 | Chart history → |
| 55 | Keep Holding OnAvril Lavigne | 53 | Chart history → |
| 56 | On The HotlinePretty Ricky | 48 | Chart history → |
| 57 | Top BackT.I. | 56 | Chart history → |
| 58 | Settlin'Sugarland | 60 | Chart history → |
| 59 | Grace KellyMIKA | 57 | Chart history → |
| 60 | Teardrops On My GuitarTaylor Swift | 70 | Chart history → |
| 61 | StandRascal Flatts | 66 | Chart history → |
| 62 | Read My MindThe Killers | 64 | Chart history → |
| 63 | We Takin' OverDJ Khaled Featuring T.I., Akon, Rick Ross, Fat Joe, Lil' Wayne & Baby | 75 | Chart history → |
| 64 | Look After YouThe Fray | 59 | Chart history → |
| 65 | StolenDashboard Confessional | — | Chart history → |
| 66 | Hey There DelilahPlain White T's | 79 | Chart history → |
| 67 | Beer In MexicoKenny Chesney | 61 | Chart history → |
| 68 | Good DirectionsBilly Currington | 72 | Chart history → |
| 69 | Into The OceanBlue October | 65 | Chart history → |
| 70 | PainThree Days Grace | 68 | Chart history → |
| 71 | The RiverGood Charlotte Featuring M. Shadows And Synyster Gates | 39 | Chart history → |
| 72 | Poppin'Chris Brown Featuring Jay Biz | 67 | Chart history → |
| 73 | Little WondersRob Thomas | 78 | Chart history → |
| 74 | Stupid BoyKeith Urban | 69 | Chart history → |
| 75 | Lost In This MomentBig & Rich | 74 | Chart history → |
| 76 | Upgrade UBeyonce Featuring Jay Z | 80 | Chart history → |
| 77 | I'll Wait For YouJoe Nichols | 71 | Chart history → |
| 78 | I TriedBone Thugs-N-Harmony Featuring Akon | 82 | Chart history → |
| 79 | Long Trip AloneDierks Bentley | 73 | Chart history → |
| 80 | High Maintenance WomanToby Keith | 76 | Chart history → |
| 81 | Kiss The GirlAshley Tisdale | — | Chart history → |
| 82 | MomentsEmerson Drive | 83 | Chart history → |
| 83 | DiamondsFabolous Featuring Young Jeezy | — | Chart history → |
| 84 | Makes Me WonderMaroon 5 | — | Chart history → |
| 85 | Year 3000Jonas Brothers | 90 | Chart history → |
| 86 | Say OKVanessa Hudgens | — | Chart history → |
| 87 | Ladies Love Country BoysTrace Adkins | 77 | Chart history → |
| 88 | A Woman's LoveAlan Jackson | 89 | Chart history → |
| 89 | Like ThisKelly Rowland Featuring Eve | 98 | Chart history → |
| 90 | ForeverPapa Roach | 95 | Chart history → |
| 91 | ReleaseTimbaland Featuring Justin Timberlake | — | Chart history → |
| 92 | Please Don't GoTank | 86 | Chart history → |
| 93 | BreathBreaking Benjamin | 97 | Chart history → |
| 94 | Find Out Who Your Friends AreTracy Lawrence | — | Chart history → |
| 95 | ApologizeTimbaland Featuring OneRepublic | — | Chart history → |
| 96 | Get BuckYoung Buck | 87 | Chart history → |
| 97 | SmileLily Allen | 96 | Chart history → |
| 98 | You Know I'm No GoodAmy Winehouse | 91 | Chart history → |
| 99 | When I See UFantasia | — | Chart history → |
| 100 | RehabAmy Winehouse | 84 | Chart history → |