| 1 | No OneAlicia Keys | 1 | Chart history → |
| 2 | ApologizeTimbaland Featuring OneRepublic | 3 | Chart history → |
| 3 | LowFlo Rida Featuring T-Pain | 4 | Chart history → |
| 4 | Kiss KissChris Brown Featuring T-Pain | 2 | Chart history → |
| 5 | ClumsyFergie | 6 | Chart history → |
| 6 | BubblyColbie Caillat | 5 | Chart history → |
| 7 | Hate That I Love YouRihanna Featuring Ne-Yo | 9 | Chart history → |
| 8 | ParalyzerFinger Eleven | 10 | Chart history → |
| 9 | Good LifeKanye West Featuring T-Pain | 7 | Chart history → |
| 10 | TattooJordin Sparks | 11 | Chart history → |
| 11 | Crank That (Soulja Boy)Soulja Boy Tell'em | 8 | Chart history → |
| 12 | CycloneBaby Bash Featuring T-Pain | 12 | Chart history → |
| 13 | StrongerKanye West | 13 | Chart history → |
| 14 | Can't Help But WaitTrey Songz | 19 | Chart history → |
| 15 | Duffle Bag BoyPlayaz Circle Featuring Lil Wayne | 18 | Chart history → |
| 16 | HypnotizedPlies Featuring Akon | 21 | Chart history → |
| 17 | The Way I AreTimbaland Featuring Keri Hilson | 14 | Listen & explore → |
| 18 | Love Like ThisNatasha Bedingfield Featuring Sean Kingston | 20 | Chart history → |
| 19 | Like You'll Never See Me AgainAlicia Keys | 29 | Chart history → |
| 20 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | 32 | Chart history → |
| 21 | Take You ThereSean Kingston | 27 | Chart history → |
| 22 | Our SongTaylor Swift | 24 | Chart history → |
| 23 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 17 | Chart history → |
| 24 | Shawty Is A 10The-Dream | 23 | Chart history → |
| 25 | How Far We've Comematchbox twenty | 16 | Chart history → |
| 26 | I'm So HoodDJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross & Plies | 25 | Chart history → |
| 27 | Over YouDaughtry | 22 | Chart history → |
| 28 | BedJ. Holiday | 15 | Chart history → |
| 29 | Just FineMary J. Blige | 26 | Chart history → |
| 30 | Teardrops On My GuitarTaylor Swift | 44 | Chart history → |
| 31 | I Don't Wanna Be In Love (Dance Floor Anthem)Good Charlotte | 31 | Chart history → |
| 32 | Big Girls Don't CryFergie | 28 | Chart history → |
| 33 | Into The NightSantana Featuring Chad Kroeger | 37 | Chart history → |
| 34 | Misery BusinessParamore | 40 | Chart history → |
| 35 | StaySugarland | 38 | Chart history → |
| 36 | Who KnewP!nk | 30 | Chart history → |
| 37 | Shadow Of The DayLinkin Park | 50 | Chart history → |
| 38 | Wake Up CallMaroon 5 | 33 | Chart history → |
| 39 | Soulja GirlSoulja Boy Tell'em Featuring I-15 | 34 | Chart history → |
| 40 | With YouChris Brown | 72 | Chart history → |
| 41 | Don't BlinkKenny Chesney | 39 | Chart history → |
| 42 | Shoulda Let You GoKeyshia Cole Introducing Amina | 41 | Chart history → |
| 43 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 35 | Chart history → |
| 44 | GirlfriendBow Wow & Omarion | 46 | Chart history → |
| 45 | SuffocateJ. Holiday | 53 | Chart history → |
| 46 | RockstarNickelback | 43 | Chart history → |
| 47 | My Drink N' My 2 StepCassidy Featuring Swizz Beatz | 45 | Chart history → |
| 48 | Get Buck In HereDJ Felli Fel Featuring Diddy, Akon, Ludacris & Lil Jon | 48 | Chart history → |
| 49 | Piece Of MeBritney Spears | 47 | Chart history → |
| 50 | Flashing LightsKanye West Featuring Dwele | 57 | Listen & explore → |
| 51 | Sensual SeductionSnoop Dogg | 76 | Chart history → |
| 52 | So SmallCarrie Underwood | 36 | Chart history → |
| 53 | FirecrackerJosh Turner | 51 | Chart history → |
| 54 | How 'Bout Them CowgirlsGeorge Strait | 49 | Chart history → |
| 55 | Ready, Set, Don't GoBilly Ray Cyrus With Miley Cyrus | 54 | Chart history → |
| 56 | Pop BottlesBirdman Featuring Lil Wayne | 64 | Chart history → |
| 57 | Baby Don't GoFabolous Featuring Jermaine Dupri | 42 | Chart history → |
| 58 | The PretenderFoo Fighters | 59 | Chart history → |
| 59 | What Do Ya Think About ThatMontgomery Gentry | 60 | Chart history → |
| 60 | Gimme MoreBritney Spears | 52 | Listen & explore → |
| 61 | Winner At A Losing GameRascal Flatts | 61 | Chart history → |
| 62 | Fake ItSeether | 62 | Chart history → |
| 63 | Letter To MeBrad Paisley | 70 | Chart history → |
| 64 | FallClay Walker | 55 | Chart history → |
| 65 | Work ThatMary J. Blige | 91 | Chart history → |
| 66 | EverybodyKeith Urban | 67 | Chart history → |
| 67 | Don't Stop The MusicRihanna | 88 | Listen & explore → |
| 68 | Roc Boys (And The Winner Is)...JAY-Z | 63 | Chart history → |
| 69 | More Than A MemoryGarth Brooks | 56 | Chart history → |
| 70 | IndependentWebbie Featuring Lil' Phat & Lil' Boosie | 87 | Chart history → |
| 71 | Never Too LateThree Days Grace | 79 | Chart history → |
| 72 | Love SongSara Bareilles | 93 | Chart history → |
| 73 | Watching AirplanesGary Allan | 74 | Chart history → |
| 74 | Livin' Our Love SongJason Michael Carroll | 58 | Chart history → |
| 75 | Hood FiggaGorilla Zoe | 66 | Chart history → |
| 76 | As IfSara Evans | 69 | Chart history → |
| 77 | Freaky GurlGucci Mane | 71 | Chart history → |
| 78 | Calabria 2008Enur Featuring Natasja | 86 | Chart history → |
| 79 | Free And Easy (Down The Road I Go)Dierks Bentley | 65 | Chart history → |
| 80 | Take Me ThereRascal Flatts | 73 | Chart history → |
| 81 | Nothin' Better To DoLeAnn Rimes | 77 | Chart history → |
| 82 | Bleed It OutLinkin Park | 83 | Chart history → |
| 83 | S.O.S.Jonas Brothers | 78 | Chart history → |
| 84 | Hero/HeroineBoys Like Girls | — | Chart history → |
| 85 | Pictures Of YouThe Last Goodnight | 82 | Chart history → |
| 86 | SorryBuckcherry | — | Chart history → |
| 87 | MistletoeColbie Caillat | 75 | Chart history → |
| 88 | Taking ChancesCeline Dion | 68 | Chart history → |
| 89 | Me EnamoraJuanes | 81 | Chart history → |
| 90 | Stealing CinderellaChuck Wicks | 90 | Chart history → |
| 91 | Cleaning This Gun (Come On In Boy)Rodney Atkins | 94 | Chart history → |
| 92 | The Way I AmIngrid Michaelson | 100 | Chart history → |
| 93 | Go GirlPitbull Featuring Trina & Young Bo$$ | 92 | Chart history → |
| 94 | See You AgainMiley Cyrus | — | Chart history → |
| 95 | NeverJaheim | — | Chart history → |
| 96 | This ChristmasChris Brown | 80 | Chart history → |
| 97 | Crying Out For MeMario | 97 | Chart history → |
| 98 | International HarvesterCraig Morgan | 99 | Chart history → |
| 99 | If You're Reading ThisTim McGraw | 89 | Chart history → |
| 100 | SayJohn Mayer | 85 | Chart history → |