| 1 | Live Your LifeT.I. Featuring Rihanna | 1 | Chart history → |
| 2 | Single Ladies (Put A Ring On It)Beyonce | 28 | Chart history → |
| 3 | If I Were A BoyBeyonce | 3 | Chart history → |
| 4 | Whatever You LikeT.I. | 2 | Chart history → |
| 5 | Hot N ColdKaty Perry | 4 | Chart history → |
| 6 | Love LockdownKanye West | 9 | Chart history → |
| 7 | Just DanceLady Gaga Featuring Colby O'Donis | 16 | Chart history → |
| 8 | So WhatP!nk | 5 | Chart history → |
| 9 | Miss IndependentNe-Yo | 11 | Chart history → |
| 10 | Right Now (Na Na Na)Akon | 8 | Chart history → |
| 11 | Let It RockKevin Rudolf Featuring Lil Wayne | 6 | Chart history → |
| 12 | WomanizerBritney Spears | 7 | Chart history → |
| 13 | I'm YoursJason Mraz | 10 | Chart history → |
| 14 | Love StoryTaylor Swift | 18 | Chart history → |
| 15 | Can't Believe ItT-Pain Featuring Lil Wayne | 14 | Chart history → |
| 16 | Mrs. OfficerLil Wayne Featuring Bobby Valentino & Kidd Kidd | 19 | Chart history → |
| 17 | DisturbiaRihanna | 15 | Chart history → |
| 18 | Better In TimeLeona Lewis | 17 | Chart history → |
| 19 | Gotta Be SomebodyNickelback | 20 | Chart history → |
| 20 | Chicken FriedZac Brown Band | 22 | Chart history → |
| 21 | HeartlessKanye West | 12 | Listen & explore → |
| 22 | AddictedSaving Abel | 23 | Chart history → |
| 23 | CrushDavid Archuleta | 21 | Chart history → |
| 24 | Green LightJohn Legend Featuring Andre 3000 | 31 | Chart history → |
| 25 | SpotlightJennifer Hudson | 27 | Chart history → |
| 26 | Keeps Gettin' BetterChristina Aguilera | 24 | Chart history → |
| 27 | Viva La VidaColdplay | 25 | Listen & explore → |
| 28 | You Found MeThe Fray | — | Chart history → |
| 29 | CloserNe-Yo | 26 | Chart history → |
| 30 | Chopped 'N' SkrewedT-Pain Featuring Ludacris | 39 | Chart history → |
| 31 | Bust Your WindowsJazmine Sullivan | 38 | Chart history → |
| 32 | Swagga Like UsJay-Z & T.I. Featuring Kanye West & Lil Wayne | 30 | Chart history → |
| 33 | Pop ChampagneJim Jones & Ron Browz Featuring Juelz Santana | 50 | Chart history → |
| 34 | RehabRihanna | 61 | Chart history → |
| 35 | Fall For YouSecondhand Serenade | 32 | Chart history → |
| 36 | Just A DreamCarrie Underwood | 29 | Chart history → |
| 37 | Shattered (Turn The Car Around)O.A.R. | 42 | Chart history → |
| 38 | One More DrinkLudacris Co-Starring T-Pain | 54 | Chart history → |
| 39 | Paper PlanesM.I.A. | 33 | Chart history → |
| 40 | ForeverChris Brown | 37 | Chart history → |
| 41 | Roll With MeMontgomery Gentry | 45 | Chart history → |
| 42 | Love Remains The SameGavin Rossdale | 41 | Chart history → |
| 43 | T-ShirtShontelle | 44 | Chart history → |
| 44 | I'd Come For YouNickelback | — | Chart history → |
| 45 | DecodeParamore | 53 | Chart history → |
| 46 | My LifeThe Game Featuring Lil Wayne | 40 | Chart history → |
| 47 | Let It GoTim McGraw | 58 | Chart history → |
| 48 | Already GoneSugarland | 51 | Chart history → |
| 49 | Got MoneyLil Wayne Featuring T-Pain | 36 | Chart history → |
| 50 | KrazyPitbull Featuring Lil Jon | 47 | Chart history → |
| 51 | SwingSavage Featuring Soulja Boy Tell'em | 52 | Chart history → |
| 52 | Don't Think I Don't Think About ItDarius Rucker | 48 | Chart history → |
| 53 | Gives You HellThe All-American Rejects | 69 | Chart history → |
| 54 | Right Here (Departed)Brandy | 57 | Chart history → |
| 55 | HereRascal Flatts | 62 | Chart history → |
| 56 | White HorseTaylor Swift | 13 | Chart history → |
| 57 | If Today Was Your Last DayNickelback | 35 | Chart history → |
| 58 | Get Up50 Cent | 71 | Chart history → |
| 59 | Start A BandBrad Paisley Duet With Keith Urban | 55 | Chart history → |
| 60 | Sweet ThingKeith Urban | 43 | Chart history → |
| 61 | Trading PlacesUsher | 80 | Chart history → |
| 62 | She Wouldn't Be GoneBlake Shelton | 91 | Chart history → |
| 63 | HumanThe Killers | 70 | Chart history → |
| 64 | Need U BadJazmine Sullivan | 60 | Chart history → |
| 65 | Sex On FireKings Of Leon | 56 | Listen & explore → |
| 66 | Everybody Wants To Go To HeavenKenny Chesney With The Wailers | 59 | Chart history → |
| 67 | In ColorJamey Johnson | 74 | Chart history → |
| 68 | Never Gonna Be AloneNickelback | — | Chart history → |
| 69 | You're Gonna Go Far, KidThe Offspring | 78 | Chart history → |
| 70 | I Don't CareFall Out Boy | 73 | Chart history → |
| 71 | Feel That FireDierks Bentley | 86 | Chart history → |
| 72 | Lookin' For A Good TimeLady Antebellum | 68 | Chart history → |
| 73 | So FlySlim Featuring Yung Joc | 64 | Chart history → |
| 74 | Come On Get HigherMatt Nathanson | 63 | Chart history → |
| 75 | Chinese DemocracyGuns N' Roses | 34 | Chart history → |
| 76 | Don'tBilly Currington | 88 | Chart history → |
| 77 | Country BoyAlan Jackson | 89 | Chart history → |
| 78 | Love RemembersCraig Morgan | 84 | Chart history → |
| 79 | Cowgirls Don't CryBrooks & Dunn Featuring Reba McEntire | 85 | Chart history → |
| 80 | Waitin' On A WomanBrad Paisley | 66 | Chart history → |
| 81 | What About NowDaughtry | 76 | Chart history → |
| 82 | Another Way to DieJack White & Alicia Keys | 81 | Chart history → |
| 83 | Playa Cardz RightKeyshia Cole Featuring 2Pac | 99 | Chart history → |
| 84 | I'm So PaidAkon Featuring Lil Wayne & Young Jeezy | 93 | Chart history → |
| 85 | She Never Cried In Front Of MeToby Keith | 77 | Chart history → |
| 86 | Do You Believe Me NowJimmy Wayne | 96 | Chart history → |
| 87 | I Don't CareApocalyptica Featuring Adam Gontier | 98 | Chart history → |
| 88 | I'll WalkBucky Covington | 83 | Chart history → |
| 89 | God Love HerToby Keith | — | Chart history → |
| 90 | RideAce Hood Featuring Trey Songz | — | Chart history → |
| 91 | Light OnDavid Cook | 82 | Chart history → |
| 92 | Put It On YaPlies Featuring Chris J | — | Chart history → |
| 93 | All Summer LongThe Rock Heroes | 67 | Chart history → |
| 94 | IfULeaveMusiq Soulchild Featuring Mary J. Blige | — | Chart history → |
| 95 | BrokenLifehouse | 100 | Chart history → |
| 96 | Did You WrongPleasure P | — | Chart history → |
| 97 | No Me Doy Por VencidoLuis Fonsi | — | Chart history → |
| 98 | LovebugJonas Brothers | 75 | Chart history → |
| 99 | What Them Girls LikeLudacris Co-Starring Chris Brown & Sean Garrett | 92 | Chart history → |
| 100 | Anything GoesRandy Houser | — | Chart history → |