| 1 | Single Ladies (Put A Ring On It)Beyonce | 2 | Chart history → |
| 2 | Live Your LifeT.I. Featuring Rihanna | 1 | Chart history → |
| 3 | If I Were A BoyBeyonce | 3 | Chart history → |
| 4 | Whatever You LikeT.I. | 4 | Chart history → |
| 5 | Just DanceLady Gaga Featuring Colby O'Donis | 7 | Chart history → |
| 6 | Hot N ColdKaty Perry | 5 | Chart history → |
| 7 | Miss IndependentNe-Yo | 9 | Chart history → |
| 8 | So WhatP!nk | 8 | Chart history → |
| 9 | WomanizerBritney Spears | 12 | Chart history → |
| 10 | I'm YoursJason Mraz | 13 | Chart history → |
| 11 | Right Now (Na Na Na)Akon | 10 | Chart history → |
| 12 | Love StoryTaylor Swift | 14 | Chart history → |
| 13 | Love LockdownKanye West | 6 | Chart history → |
| 14 | Let It RockKevin Rudolf Featuring Lil Wayne | 11 | Chart history → |
| 15 | You Found MeThe Fray | 28 | Chart history → |
| 16 | Gotta Be SomebodyNickelback | 19 | Chart history → |
| 17 | Mrs. OfficerLil Wayne Featuring Bobby Valentino & Kidd Kidd | 16 | Chart history → |
| 18 | DisturbiaRihanna | 17 | Chart history → |
| 19 | HeartlessKanye West | 21 | Listen & explore → |
| 20 | Can't Believe ItT-Pain Featuring Lil Wayne | 15 | Chart history → |
| 21 | See You In My NightmaresKanye West Featuring Lil Wayne | — | Chart history → |
| 22 | Better In TimeLeona Lewis | 18 | Chart history → |
| 23 | Chicken FriedZac Brown Band | 20 | Chart history → |
| 24 | AddictedSaving Abel | 22 | Chart history → |
| 25 | One More DrinkLudacris Co-Starring T-Pain | 38 | Chart history → |
| 26 | Green LightJohn Legend Featuring Andre 3000 | 24 | Chart history → |
| 27 | CrushDavid Archuleta | 23 | Chart history → |
| 28 | RehabRihanna | 34 | Chart history → |
| 29 | Viva La VidaColdplay | 27 | Listen & explore → |
| 30 | Chopped 'N' SkrewedT-Pain Featuring Ludacris | 30 | Chart history → |
| 31 | CloserNe-Yo | 29 | Chart history → |
| 32 | Pop ChampagneJim Jones & Ron Browz Featuring Juelz Santana | 33 | Chart history → |
| 33 | SpotlightJennifer Hudson | 25 | Chart history → |
| 34 | DecodeParamore | 45 | Chart history → |
| 35 | Bust Your WindowsJazmine Sullivan | 31 | Chart history → |
| 36 | Shattered (Turn The Car Around)O.A.R. | 37 | Chart history → |
| 37 | Swagga Like UsJay-Z & T.I. Featuring Kanye West & Lil Wayne | 32 | Chart history → |
| 38 | Keeps Gettin' BetterChristina Aguilera | 26 | Chart history → |
| 39 | ForeverChris Brown | 40 | Chart history → |
| 40 | Fall For YouSecondhand Serenade | 35 | Chart history → |
| 41 | T-ShirtShontelle | 43 | Chart history → |
| 42 | Roll With MeMontgomery Gentry | 41 | Chart history → |
| 43 | Love Remains The SameGavin Rossdale | 42 | Chart history → |
| 44 | Just A DreamCarrie Underwood | 36 | Chart history → |
| 45 | Paper PlanesM.I.A. | 39 | Chart history → |
| 46 | Already GoneSugarland | 48 | Chart history → |
| 47 | White HorseTaylor Swift | 56 | Chart history → |
| 48 | Got MoneyLil Wayne Featuring T-Pain | 49 | Chart history → |
| 49 | HumanThe Killers | 63 | Chart history → |
| 50 | Gives You HellThe All-American Rejects | 53 | Chart history → |
| 51 | Let It GoTim McGraw | 47 | Chart history → |
| 52 | My LifeThe Game Featuring Lil Wayne | 46 | Chart history → |
| 53 | SoberP!nk | — | Chart history → |
| 54 | Right Here (Departed)Brandy | 54 | Chart history → |
| 55 | KrazyPitbull Featuring Lil Jon | 50 | Chart history → |
| 56 | SwingSavage Featuring Soulja Boy Tell'em | 51 | Chart history → |
| 57 | HereRascal Flatts | 55 | Chart history → |
| 58 | Trading PlacesUsher | 61 | Chart history → |
| 59 | She Wouldn't Be GoneBlake Shelton | 62 | Chart history → |
| 60 | Light OnDavid Cook | 91 | Chart history → |
| 61 | Start A BandBrad Paisley Duet With Keith Urban | 59 | Chart history → |
| 62 | UntouchedThe Veronicas | — | Chart history → |
| 63 | I Don't CareFall Out Boy | 70 | Chart history → |
| 64 | Get Up50 Cent | 58 | Chart history → |
| 65 | Last Of A Dying BreedLudacris Co-Starring Lil Wayne | — | Chart history → |
| 66 | I'm So PaidAkon Featuring Lil Wayne & Young Jeezy | 84 | Chart history → |
| 67 | In ColorJamey Johnson | 67 | Chart history → |
| 68 | You're Gonna Go Far, KidThe Offspring | 69 | Chart history → |
| 69 | Sweet ThingKeith Urban | 60 | Chart history → |
| 70 | Come On Get HigherMatt Nathanson | 74 | Chart history → |
| 71 | Feel That FireDierks Bentley | 71 | Chart history → |
| 72 | Sex On FireKings Of Leon | 65 | Listen & explore → |
| 73 | Country BoyAlan Jackson | 77 | Chart history → |
| 74 | Lookin' For A Good TimeLady Antebellum | 72 | Chart history → |
| 75 | Don'tBilly Currington | 76 | Chart history → |
| 76 | Everybody Wants To Go To HeavenKenny Chesney With The Wailers | 66 | Chart history → |
| 77 | So FlySlim Featuring Yung Joc | 73 | Chart history → |
| 78 | Love RemembersCraig Morgan | 78 | Chart history → |
| 79 | I Hate This PartThe Pussycat Dolls | — | Chart history → |
| 80 | Cowgirls Don't CryBrooks & Dunn Featuring Reba McEntire | 79 | Chart history → |
| 81 | Need U BadJazmine Sullivan | 64 | Chart history → |
| 82 | Chinese DemocracyGuns N' Roses | 75 | Chart history → |
| 83 | IfULeaveMusiq Soulchild Featuring Mary J. Blige | 94 | Chart history → |
| 84 | What About NowDaughtry | 81 | Chart history → |
| 85 | Playa Cardz RightKeyshia Cole Featuring 2Pac | 83 | Chart history → |
| 86 | God Love HerToby Keith | 89 | Chart history → |
| 87 | Lost!Coldplay With Jay-Z | — | Chart history → |
| 88 | Put It On YaPlies Featuring Chris J | 92 | Chart history → |
| 89 | AmazingKanye West Featuring Young Jeezy | — | Chart history → |
| 90 | I Don't CareApocalyptica Featuring Adam Gontier | 87 | Chart history → |
| 91 | LovebugJonas Brothers | 98 | Chart history → |
| 92 | What Them Girls LikeLudacris Co-Starring Chris Brown & Sean Garrett | 99 | Chart history → |
| 93 | BrokenLifehouse | 95 | Chart history → |
| 94 | Leave Out All The RestLinkin Park | — | Chart history → |
| 95 | I'd Come For YouNickelback | 44 | Chart history → |
| 96 | Do You Believe Me NowJimmy Wayne | 86 | Chart history → |
| 97 | All Summer LongThe Rock Heroes | 93 | Chart history → |
| 98 | Second ChanceShinedown | — | Chart history → |
| 99 | Anything GoesRandy Houser | 100 | Chart history → |
| 100 | Bad GirlfriendTheory Of A Deadman | — | Chart history → |