| 1 | No OneAlicia Keys | 1 | Chart history → |
| 2 | ApologizeTimbaland Featuring OneRepublic | 3 | Chart history → |
| 3 | Kiss KissChris Brown Featuring T-Pain | 2 | Chart history → |
| 4 | LowFlo Rida Featuring T-Pain | 4 | Chart history → |
| 5 | Crank That (Soulja Boy)Soulja Boy Tell'em | 6 | Chart history → |
| 6 | BubblyColbie Caillat | 5 | Chart history → |
| 7 | ClumsyFergie | 8 | Chart history → |
| 8 | Good LifeKanye West Featuring T-Pain | 7 | Chart history → |
| 9 | Hate That I Love YouRihanna Featuring Ne-Yo | 12 | Chart history → |
| 10 | CycloneBaby Bash Featuring T-Pain | 9 | Chart history → |
| 11 | ParalyzerFinger Eleven | 11 | Chart history → |
| 12 | TattooJordin Sparks | 16 | Chart history → |
| 13 | StrongerKanye West | 10 | Chart history → |
| 14 | The Way I AreTimbaland Featuring Keri Hilson | 13 | Listen & explore → |
| 15 | How Far We've Comematchbox twenty | 15 | Chart history → |
| 16 | BedJ. Holiday | 14 | Chart history → |
| 17 | Duffle Bag BoyPlayaz Circle Featuring Lil Wayne | 22 | Chart history → |
| 18 | Over YouDaughtry | 19 | Chart history → |
| 19 | Shawty Is A 10The-Dream | 18 | Chart history → |
| 20 | Big Girls Don't CryFergie | 17 | Chart history → |
| 21 | Love Like ThisNatasha Bedingfield Featuring Sean Kingston | 27 | Chart history → |
| 22 | I'm So HoodDJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross & Plies | 24 | Chart history → |
| 23 | Our SongTaylor Swift | 28 | Chart history → |
| 24 | HypnotizedPlies Featuring Akon | 32 | Chart history → |
| 25 | Can't Help But WaitTrey Songz | 30 | Chart history → |
| 26 | I Don't Wanna Be In Love (Dance Floor Anthem)Good Charlotte | 35 | Chart history → |
| 27 | Ayo Technology50 Cent Featuring Justin Timberlake & Timbaland | 21 | Chart history → |
| 28 | So SmallCarrie Underwood | 23 | Chart history → |
| 29 | Wake Up CallMaroon 5 | 25 | Chart history → |
| 30 | Who KnewP!nk | 20 | Chart history → |
| 31 | Take You ThereSean Kingston | 42 | Chart history → |
| 32 | Soulja GirlSoulja Boy Tell'em Featuring I-15 | 37 | Chart history → |
| 33 | Until The End Of TimeJustin Timberlake Duet With Beyonce | 26 | Chart history → |
| 34 | RockstarNickelback | 31 | Chart history → |
| 35 | Baby Don't GoFabolous Featuring Jermaine Dupri | 34 | Chart history → |
| 36 | Just FineMary J. Blige | 43 | Chart history → |
| 37 | Sweetest Girl (Dollar Bill)Wyclef Jean Featuring Akon, Lil Wayne & Niia | 44 | Chart history → |
| 38 | Don't BlinkKenny Chesney | 33 | Chart history → |
| 39 | Into The NightSantana Featuring Chad Kroeger | 38 | Chart history → |
| 40 | StaySugarland | 36 | Chart history → |
| 41 | My Drink N' My 2 StepCassidy Featuring Swizz Beatz | 40 | Chart history → |
| 42 | Gimme MoreBritney Spears | 29 | Listen & explore → |
| 43 | Misery BusinessParamore | 48 | Chart history → |
| 44 | UmbrellaRihanna Featuring Jay-Z | 50 | Chart history → |
| 45 | Shoulda Let You GoKeyshia Cole Introducing Amina | 49 | Chart history → |
| 46 | Like You'll Never See Me AgainAlicia Keys | 45 | Chart history → |
| 47 | Hey There DelilahPlain White T's | 39 | Chart history → |
| 48 | Get Buck In HereDJ Felli Fel Featuring Diddy, Akon, Ludacris & Lil Jon | 41 | Chart history → |
| 49 | Let It GoKeyshia Cole Featuring Missy Elliott & Lil Kim | 46 | Chart history → |
| 50 | How 'Bout Them CowgirlsGeorge Strait | 51 | Chart history → |
| 51 | FirecrackerJosh Turner | 53 | Chart history → |
| 52 | Livin' Our Love SongJason Michael Carroll | 56 | Chart history → |
| 53 | More Than A MemoryGarth Brooks | 55 | Chart history → |
| 54 | Shadow Of The DayLinkin Park | 70 | Chart history → |
| 55 | FallClay Walker | 57 | Chart history → |
| 56 | GirlfriendBow Wow & Omarion | 62 | Chart history → |
| 57 | S.O.S.Jonas Brothers | 74 | Chart history → |
| 58 | Ready, Set, Don't GoBilly Ray Cyrus With Miley Cyrus | 65 | Chart history → |
| 59 | Hood FiggaGorilla Zoe | 59 | Chart history → |
| 60 | The PretenderFoo Fighters | 58 | Chart history → |
| 61 | Free And Easy (Down The Road I Go)Dierks Bentley | 52 | Chart history → |
| 62 | Freaky GurlGucci Mane | 69 | Chart history → |
| 63 | Piece Of MeBritney Spears | 80 | Chart history → |
| 64 | Roc Boys (And The Winner Is)...JAY-Z | 64 | Chart history → |
| 65 | What Do Ya Think About ThatMontgomery Gentry | 73 | Chart history → |
| 66 | Take Me ThereRascal Flatts | 61 | Chart history → |
| 67 | Fake ItSeether | 67 | Chart history → |
| 68 | Taking ChancesCeline Dion | 54 | Chart history → |
| 69 | As IfSara Evans | 72 | Chart history → |
| 70 | Winner At A Losing GameRascal Flatts | 79 | Chart history → |
| 71 | EverybodyKeith Urban | 71 | Chart history → |
| 72 | SuffocateJ. Holiday | 84 | Chart history → |
| 73 | Pop BottlesBirdman Featuring Lil Wayne | 87 | Chart history → |
| 74 | I'm Like A Lawyer...(Me & You)Fall Out Boy | 68 | Chart history → |
| 75 | Flashing LightsKanye West Featuring Dwele | — | Listen & explore → |
| 76 | OnlineBrad Paisley | 66 | Chart history → |
| 77 | Never Too LateThree Days Grace | 81 | Chart history → |
| 78 | Music Is My Hot Hot SexCSS | 63 | Chart history → |
| 79 | Nothin' Better To DoLeAnn Rimes | 75 | Chart history → |
| 80 | Watching AirplanesGary Allan | 83 | Chart history → |
| 81 | Pictures Of YouThe Last Goodnight | 77 | Chart history → |
| 82 | Me EnamoraJuanes | 82 | Chart history → |
| 83 | Bleed It OutLinkin Park | 78 | Chart history → |
| 84 | If You're Reading ThisTim McGraw | 76 | Chart history → |
| 85 | Letter To MeBrad Paisley | 89 | Chart history → |
| 86 | MistletoeColbie Caillat | — | Chart history → |
| 87 | Sorry, Blame It On MeAkon | 93 | Chart history → |
| 88 | Do It WellJennifer Lopez | 86 | Chart history → |
| 89 | This ChristmasChris Brown | — | Chart history → |
| 90 | Calabria 2008Enur Featuring Natasja | 97 | Chart history → |
| 91 | Love SongSara Bareilles | 92 | Chart history → |
| 92 | The Hand ClapHurricane Chris Featuring Big Poppa | 91 | Chart history → |
| 93 | Me LoveSean Kingston | 95 | Chart history → |
| 94 | Don't Stop The MusicRihanna | — | Listen & explore → |
| 95 | HotAvril Lavigne | — | Chart history → |
| 96 | 1234Feist | 85 | Chart history → |
| 97 | I Get Money50 Cent | 98 | Chart history → |
| 98 | Stealing CinderellaChuck Wicks | 94 | Chart history → |
| 99 | IndependentWebbie Featuring Lil' Phat & Lil' Boosie | — | Chart history → |
| 100 | Cleaning This Gun (Come On In Boy)Rodney Atkins | — | Chart history → |